PRENOSOLOGICAL DIAGNOSIS AND PREVENTION OF CARDIOVASCULAR DISEASE IN PEOPLE EXPOSED TO RADIATION, BASED ON THE STUDY OF GENE POLYMORPHISM
The paper presents the principles of prenosological diagnosis for socially significant cardiovascular diseases by identifying of polymorphisms in the candidate genes that determine blood pressure levels, metabolism of homocysteineand lipids. The study allowed establish a high correlation between heterozygous violations of the candidate gene AGT, which implies a high degree of inheritance of vascular pathology of radiation-exposed parents to their offspring. The research results indicate the necessary for improving of long-term monitoring, including screening and treatment for primary and secondary prevention of cardiovascular events among persons who are descendants of population exposed to radiation.
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Т.К. Рахыпбеков, Т.А. Адылханов, А.К. Мусаханова, Н.Е. Аукенов, Л.М. Пивина, Т.И. Белихина, А.С. Керимкулова ДОНОЗОЛОГИЧЕСКАЯ ДИАГНОСТИКА И ПРОФИЛАКТИКА БОЛЕЗНЕЙ СИСТЕМЫ КРОВООБРАЩЕНИЯ У ЛИЦ, ПОДВЕРГАВШИХСЯ ВОЗДЕЙСТВИЮ РАДИАЦИОННОГО ФАКТОРА, НА ОСНОВЕ ИЗУЧЕНИЯ ГЕННОГО ПОЛИМОРФИЗМА. //НАУКА И ЗДРАВООХРАНЕНИЕ 2012.№ 3. С. 18-20 T.K. Rakhypbekov, T.A. Adylkhanov, A.K. Musakhanova, N.E. Aukenov, L.M. Pivina, T.I. Belikhina, A.S. Kerimkulova PRENOSOLOGICAL DIAGNOSIS AND PREVENTION OF CARDIOVASCULAR DISEASE IN PEOPLE EXPOSED TO RADIATION, BASED ON THE STUDY OF GENE POLYMORPHISM . // NAUKA I ZDRAVOOKHRANENIE 2012.№ 3. С. 18-20 .К. Рахыпбеков, Т.А. Адылханов, А.К. Мусаханова, Н.Е. Аукенов, Л.М. Пивина, Т.И. Белихина, А.С. Керимкулова ГЕНДІК ПОЛИМОРФИЗМДІ ЗЕРТТЕУ НЕГІЗІНДЕ РАДИЯЦИЯЛЫҚ ФАКТОРДЫҢ ӘСЕРІНЕ ТҮСКЕН ҚАН АЙНАЛЫМ ЖҮЙЕСІНДЕГІ НОЗОЛОГИЯҒАДЕЙІНГІАУРУЛАРДЫҢ ДИАГНОСТИКАСЫЖӘНЕПРОФИЛАКТИКАСЫ . // ҒЫЛЫМ ЖӘНЕ ДЕНСАУЛЫҚ САҚТАУ. 2012.№ 3. С. 18-20Related publications:
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PRENOSOLOGICAL DIAGNOSIS AND PREVENTION OF CARDIOVASCULAR DISEASE IN PEOPLE EXPOSED TO RADIATION, BASED ON THE STUDY OF GENE POLYMORPHISM