TREATMENT OF PATIENTS WITH DRY AGE-RELATED MACULAR DEGENERATION WITH LUTEIN-CONTAINING VITAMIN-MINERAL COMPLEX: THE OUTCOMES OF ONE-YEAR STUDY
Background: Age-related macular degeneretation is the major cause of blinness in developed world nations.
Aim: to evaluate the clinical effectiveness of Slezavit in the treatment of patients with dry of age-related macular degeneration.
Methods: This was a controlled clinical trial that included 34 patients from the study group and 29 patients from the control group who were examined by visometry, subjective refractometry, direct ophthalmoscopy, optical coherence tomography (OCT) and were interviewed for self-appraisal of their central vision (at the beginning of the study and one year later). The study hold at "Ophthalmic Microsurgery" Hospital, Semey, in the period from 19 December, 2016 to 25 December, 2017.
The statistical data treatment was carried out with the help of SPSS (Statistical Package for the Social Sciences, licenced by Semey Medical University). Proportions, means and standard error (SE) were used for the analysis of quantitative data. The level of statistical significance was preset at р≤0,05.
Results: There was a slight increase in visual acuity in patients from the study group, who consumed one capsule of Slezavit once a day per 3 months. At the same time, there was a slight deterioration in visual acuity of patients in the control group, who did not take any vitamin-mineral complexes. Also, patients from the control group witnessed the ARMD progression, which was manifested as deterioration of the ARMD category. Patients in the "Slezavit" group had a decrease in the thickness of the macula within 3 mm zone, based on OCT, and experienced improvement in the subjective perception of the state of their visual functions compared to the patients from the control group in whom negative dynamics were detected.
Conclusion: prescription of Slezavit to the patients with dry AMD has a beneficial effect on the state of their visual functions, reduction of macula swelling and subjective perception of central vision, compared with the patients who did not take any vitamin-mineral complexes.
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Semenova Yu.M., Turusbekova U.K., Kairbekova A.E., Magauina D.D., Kampik Anselm, Yurkovskiy A.O. Treatment of patients with dry age-related macular degeneration with lutein-containing vitamin-mineral complex: the outcomes of one-year study // Nauka i Zdravookhranenie [Science & Healthcare]. 2020, (Vol.22) 1, pp. 80-87. doi:10.34689/SH.2020.22.1.009Related publications:
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