NEED OF IMPROVING THE DIAGNOSTICS OF VIRAL HEPATITIS C IN PATIENTS WITH CHRONIC KIDNEY DISEASE, RECEIVING HEMODIALYSIS
This article presents a retrospective analysis of laboratory parameters in patients with end-stage chronic renal failure receiving lifelong hemodialysis and having a positive test for viral hepatitis C. The indicators of the complete blood count (red blood cell count, leukocyte count, platelet count, hemoglobin concentration, hematocrit and ESR) were analyzed, biochemical studies for glucose, total protein, albumin, renal functional tests (glomerular filtration rate - GFR, creatine and urea), liver function tests (ALT and AST), iron examination (concentration of serum iron and ferritin), C-reactive protein. For the diagnosis of viral hepatitis C, only the test for the determination of antibodies against viral hepatitis antiHCV (Hepatitis C virus) was used. A statistical analysis of the obtained data was carried out - the number and percentage, the arithmetic average, the level of significance P at ≤ 0.05. Assessment of the terminal stage of chronic renal failure in terms of sexual dimorphism in a comprehensive study of the diagnosis of hepatitis C in patients receiving hemodialysis was made for the first time. Fluctuations in individual diagnostic and prognostic indicators of laboratory tests, suggesting the involvement of sex factors in the combined development of viral hepatitis C and chronic renal failure were identified with an unfavorable prognosis. An important conclusion was made that, in order to improve diagnosis, it is necessary to follow the algorithm for early diagnosis of viral hepatitis C in patients with chronic kidney disease, who are shown to undergo dialysis, according to the guidelines of KDIGO (Kidney Disease: Improving Global Outcomes, 2018). First of all, it is necessary to include a test for determining the nucleic acids of the causative agent of viral hepatitis C - the RNA test.
Number of Views: 315
Category of articles:
Original articles
Bibliography link
Rysuly M.R., Sadvakas A.S., Rakhmetov N.R., Ramazanov M.E., Zhanbyrbay B.K., Musabaev B.S. Need of improving the diagnostics of viral hepatitis C in patients with chronic kidney disease, receiving hemodialysis // Nauka i Zdravookhranenie [Science & Healthcare]. 2020, (Vol.22) 6, pp. 54-62. doi 10.34689/SH.2020.22.6.008Related publications:
VALIDATION OF THE KAZAKH VERSION OF THE DEPRESSION ANXIETY STRESS SCALE (DASS-21) IN MEDICAL FACULTY STAFF SAMPLE: THE PILOT STUDY
PREDICTIVE VALUE OF PSYCHOMETRIC TESTING IN CONTEXT OF CREATING ADAPTIVE ENVIRONMENT FOR HIGHER MEDICAL EDUCATION
ASSESSMENT OF STUDENTS' AWARENESS ABOUT THE HARMS OF MICROPLASTICS ON THE HUMAN BODY
THE IMPACT OF COMPLAINTS ON QUALITY OF LIFE, PSYCHOLOGICAL WELL-BEING AND HEALTH OF MEDICAL WORKERS
DEVELOPMENT AND VALIDATION OF A QUESTIONNAIRE FOR PATIENTS "STUDYING THE OPINION OF PATIENTS' SATISFACTION WITH NURSE INDEPENDENT APPOINTMENT AT THE LEVEL OF PRIMARY HEALTH CARE"