BREAST CANCER RISK FACTORS
Relevance. Breast cancer is the most common cancer among women and the second most common new cancer in the world. Today, there is a wealth of data showing the influence of lifestyle and environmental factors on the development of breast cancer. These factors include a high-fat diet, alcohol consumption, and inadequate physical activity. These factors are amenable to correction, which entails a decrease in morbidity and mortality.
Purpose. Study the risk factors for breast cancer.
Materials and methods. In this review, the databases MedLine, Cochrain, PubMEd were used. Sources are studied without language limitation. The literature review was carried out in electronic and manual modes. Articles that met the inclusion and exclusion criteria were selected for the review.
For the search and selection of articles, the PRISMA principle (Preferred Reporting Method for Systematic Reviews and Meta-analyzes) was used. In this review, the databases MedLine, Cochrain, PubMEd were used. The search depth was 10 years. Selected sources have been studied without language limitation. The literature review was carried out in electronic and manual modes. For the review, articles were selected that matched the keywords - Breast cancer, primary cancer prevention, breast cancer risk factors. 715 articles were found, systematic reviews, meta-analyzes, randomized clinical trials were included in the search. To remove duplicates and select articles, the resource "https://rayyan.ai/" was used. After the selection of articles, 200 sources were selected, which were included in the final synthesis.
Results and discussion. Primary prevention has a significant impact on the incidence rate. Lifestyle and environmental factors play a big role in the development of breast cancer. At the same time, a common problem is that women's knowledge about the impact of lifestyle on the development of breast cancer is limited. There is a need to increase the level of knowledge of the female population about the risk factors for breast cancer and how to correct them.
Conclusion. The study of risk factors shows that today many factors are amenable to correction. To date, it is necessary to conduct interdisciplinary research aimed at improving prevention with an emphasis on primary preventive measures, which will reduce the impact of "correctable" risk factors. Also, due to the presence of genetic risk factors, there is a need to increase the range of application of genetic research methods.
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Shertaeva A.B., Ospanova D.A., Grzhibovsky A.M. Breast cancer risk factors // Nauka i Zdravookhranenie [Science & Healthcare]. 2022, (Vol.24) 2, pp. 167-174. doi 10.34689/SH.2022.24.2.020Related publications:
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