Relevance: Carrying out of intensive therapy at severe traumatic brain injury is a complex of measures aimed on saving of the brain tissues and maintaining its functions. To achieve this goal, it is necessary to do timely diagnostics and monitoring of critical parameters - intracranial pressure and cerebral perfusion pressure; pathogenetically based therapy and nutritional support for critically ill patients. Aim: The goal of this review was to find evidences of admissibility of use for such methods as control of cerebral perfusion pressure and intracranial pressure, anti-edematous therapy, brain hypothermia and nutritive support at severe traumatic brain injury. Materials and methods: we have reviewed all available works that met inclusion criteria for mentioned aims, that were published on PubMed, Cochrane Library and Scopus within the period from 1970 till 2018. Results and Summary: Current topics is narrow-specified, so there is lack of information and available researches in reviewed fields of neurotrauma. Additional qualitative research works on this topics should be done.
Marat K. Syzdykbayev 1, Marat B. Temirgaliev 1, Alexander A. Prokazyuk 1, Anton Sheinin 2, Daulet S. Tokenov 1, Adlet M. Mamayev 1 1 University hospital of Semey Medical University, Semey, The Republic of Kazakhstan; 2 Tel-Aviv University, Sagol School of Neuroscience, Tel-Aviv, Israel
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