ATRIAL FIBRILLATION PREDICTORS IN PATIENT WITH ACUTE CORONARY SYNDROME IN KABUL (AFGHANISTAN) FROM 2018 TO 2020
Aim: The study was aimed to find out the atrial fibrillation predictors in patient with acute coronary syndrome in Kabul, Afghanistan from 2018 to 2020. Methodology: It was a cross-sectional descriptive study based on purposive sampling conducted in three different hospitals in Kabul. The study included 1416 both male and female patients with known ACS (148 AF) aging over 20 years. Results: The mean age was 59±13 (22-95), the mean systolic BP was 128± 24 (60-210) mmHg, diastolic BP was 82±15 (40-125) mmHg, and mean BMI was 26.1±4.6 (16.1-37.7), CHA2DS2-VASc score was strongly associated with AF (P value < 0.001, 95% CI: 1.36-1.99) and the cases of AF significantly increased with increasing CHA2DS2-VASc score. In addition, mean CHA2DS2-VASC score was different across AF group (2.85 ± 1.64 vs. 2.23±1.23 P value 0.001). AF was more prevalent in hypokalemia (75.10% P value < 0.001) and the mean serum potassium was significantly different across AF group (3.83±0.66 vs. 4.28±0.62 in sinus rhythm). AF prevalence was more in the elevated WBC group (P value 0.001) and there was a strong correlation between AF and WBC (pearson correlation 0.9). Moreover, mean WBC count was different across AF group (10400 ±2900 vs. 9500±3200 in sinus rhythm. Conclusion: Atrial fibrillation is the most common heart rhythm disorder that is strongly and significantly associated with increased CHA2DS2-VASc score, elevated WBC count and low serum potassium level. Patients with these disorders should be closely monitored and serum potassium level should be kept over 3.5 mEq/L. A large cohort study is needed to propose these tests for the screening purpose of atrial fibrillation development in patients with acute coronary syndrome.
Ikramullah Ibrahimi1, Nasratullah Shinwari2, Zakirullah Sarwari1, Kairat R. Karibayev3, A .Z. Akhenbekova4 1 Department of Internal Medicine of Medical Faculty of Nangarhar University, Nangarhar Afghanistan; 2 Department of Medical Faculty of Paktia University, Paktia, Afghanistan; 3 Cardiocenter Central Clinic Hospital, Almaty c., Republic of Kazakhstan; 4 Higher School of Medicine, Faculty of Medicine and Healthcare, Al-Farabi Kazakh National University, Almaty, Republic of Kazakhstan.
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Ibrahimi I., Shinwari N., Sarwari Z., Karibayev K.R., Akhenbekova A.Z. Atrial fibrillation predictors in patient with acute coronary syndrome in Kabul (Afghanistan) from 2018 to 2020 // Nauka i Zdravookhranenie [Science & Healthcare]. 2021, (Vol.23) 3, pp. 146-152. doi 10.34689/SH.2021.23.3.017 Икрамулла И., Шинвари Н., Сарвари З., Карибаев К.Р., Ахенбекова А.Ж. Предикторы фибрилляции предсердий у пациентов с острым коронарным синдромом в Кабуле (Афганистан) с 2018 по 2020 год // Наука и Здравоохранение. 2021. 3(Т.23). С. 146-152. doi 10.34689/SH.2021.23.3.017 Икрамулла И., Шинвари Н., Сарвари З., Карибаев К.Р., Ахенбекова А.Ж. 2018 жылдан 2020 жылға дейін Ауғанстанның Кабул қаласында жедел коронарлық синдромы бар науқаста атриальды фибрилляцияны болжаушылар // Ғылым және Денсаулық сақтау. 2021. 3 (Т.23). Б. 146-152. doi 10.34689/SH.2021.23.3.017