ВЛИЯНИЕ ТОЛЩИНЫ ЭНДОМЕТРИЯ НА ИСХОД ПРОГРАММ ВСПОМОГАТЕЛЬНЫХ РЕПРОДУКТИВНЫХ ТЕХНОЛОГИЙ. ОБЗОР ЛИТЕРАТУРЫ.
Введение. Тонкий эндометрий, зафиксированный на УЗИ в процессе стимуляции яичников, по данным литературы, связан со снижением частоты наступления беременности после процедуры экстракорпорального оплодотворения (ЭКО), даже в случае отсутствия предшествующих хирургических вмешательств в полость матки либо инфекционного поражения эндометрия. Данный обзор литературы посвящён изучению влияния толщины эндометрия на исходы вспомогательных репродуктивных технологий. Цель. Изучить опыт зарубежных авторов в изучении корреляции исходов программ ВРТ с толщиной эндометрия на момент переноса эмбрионов. Стратегия поиска. Поиск литературы был осуществлен с использованием баз данных PubMed, GoogleScholar, Medline за последние 10 лет, также было включено несколько источников 1989, 1993 и 1996 годов, содержащих концептуальную информацию. Поиск производился по ключевым словам: «толщина эндометрия», «тонкий эндометрий», «вспомогательные репродуктивные технологии», «экстракорпоральное оплодотворение». Были отобраны статьи на английском языке, содержащие доказательные выводы по оценке корреляции между толщиной эндометрия и частотой наступления беременности, материнскими и перинатальными исходами у женщин, перенесших процедуру ЭКО. Результаты и выводы. Анализ данных исследований показал, что имеется закономерная корреляционная связь между толщиной эндометрия и показателями результативности программ вспомогательных репродуктивных технологий. Тонкий эндометрий снижает частоту наступления клинической беременности, а также пагубно влияет на исходы самой беременности, повышая риски невынашивания беременности и преждевременных родов.
Юлия В. Забродина1, https://orcid.org/0000-0001-8972-0300 Гайныл У. Ахмедьянова1, https://orcid.org/0000-0002-5410-7781 Зайтуна Г. Хамидуллина1, https://orcid.org/0000-0002-0902-5269 1 НАО «Медицинский университет Астана», Кафедра акушерства и гинекологии №1, г. Нур-Султан, Республика Казахстан.
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Забродина Ю.В., Ахмедьянова Г.У., Хамидуллина З.Г. Влияние толщины эндометрия на исход программ вспомогательных репродуктивных технологий. Обзор литературы // Наука и Здравоохранение. 2023. 1(Т.25). С. 223-231. doi 10.34689/SH.2023.25.1.026

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