CLINICAL CASE: POSTSTREPTOCOCCAL ARTHRITIS ASSOCIATED WITH COVID-19
Introduction: Poststreptococcal arthritis associated with COVID-19 is a rare but severe inflammatory condition that arises following a prior COVID-19 infection, contributing to complications of a preceding streptococcal infection. It serves as an example of how COVID-19 may precede and trigger autoimmune diseases. In recent years, there has been an increase in cases associated with infections linked to COVID-19, highlighting the importance of studying the long-term health consequences of the pandemic and the rising incidence of infectious disorders.
The purpose of the study: To draw the attention of rheumatologists, general practitioners, and infectious disease specialists to the risks of developing autoimmune diseases following COVID-19 infection, as well as to emphasize the importance of early diagnosis, prevention, and comprehensive management of COVID-19 to minimize long-term complications, including autoimmune disorders.
Materials and Methods: To diagnose this condition, patient anamnesis and clinical-laboratory data were collected. Additionally, a review of global publications from the last five years was conducted, examining the role of COVID-19 as a precursor to autoimmune diseases and a predictor of complications from various infectious diseases that may lead to autoimmune pathology.
Results: Based on anamnesis, clinical and laboratory, instrumental data a diagnosis of poststreptococcal arthritis associated with COVID-19 was established. The investigation results confirmed the presence of an inflammatory (streptococcal) process related to a previous COVID-19 infection, suggesting a possible link between past infection and the development of an autoimmune disorder.
Conclusions: COVID-19 causes a cytokine storm, leading to a decrease in T-lymphocyte levels, suppression of cellular immunity, and increased susceptibility to other infections. In this clinical case, poststreptococcal arthritis developed in a patient with laboratory-confirmed immune alterations following COVID-19. This case underscores the importance of primary and secondary prevention of infectious diseases, as well as the necessity of monitoring the immune status of patients who have recovered from COVID-19 to ensure timely detection and treatment of potential autoimmune complications.
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Nogayeva M.G., Atasheva A.A., Omargali K.S. Nurgalieva B.K. Clinical case: poststreptococcal arthritis associated with COVID-19 // Nauka i Zdravookhranenie [Science & Healthcare]. 2025. Vol.27 (1), pp. 267-273. doi 10.34689/SH.2025.27.1.029Похожие публикации:
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