PATHOLOGICAL CHANGES IN LUNG TISSUE UNDER THE INFLUENCE OF ELECTRONIC CIGARETTES. LITERATURE REVIEW.
Background: Electronic cigarettes (e-cigarettes) have gained substantial popularity worldwide, particularly among adolescents and young adults. Their aerosols contain nicotine, flavoring agents, propylene glycol, glycerol, and thermal degradation by-products capable of reaching the distal airways and inducing inflammatory, fibrotic, and potentially precancerous alterations. Coordinated public health measures are necessary to mitigate the global burden of e-cigarette–related respiratory disease.
Aim: To synthesize current evidence on morphological changes in lung tissue following exposure to e-cigarette aerosols.
Search strategy: A literature review was conducted using PubMed, Scopus, Google Scholar, and e-Library databases for studies published between from 2015 to March 2025. Search terms included “electronic nicotine delivery systems,” “vaping,” “lungs,” “morphology,” and “oxidative stress.” Eligible publications comprised systematic reviews and original research in English and Russian.
Results: Data analysis revealed a marked increase in e-cigarette use over the last decade. Given the direct inhalation route, pathological changes predominantly occur in lung tissue, including acute epithelial injury, chronic inflammation, and fibrotic remodeling.
Conclusions: E-cigarette aerosols exert deleterious effects on the respiratory system, with potential mechanisms involving oxidative stress, pro-inflammatory cytokine activation, and suppression of DNA repair. Further morphological and immunohistochemical studies are warranted to elucidate long-term pulmonary consequences.
Количество просмотров: 326
Категория статей:
Обзор литературы
Библиографическая ссылка
Tatykayeva U.B., Abdullayeva A.A., Sadykova K.Zh., Apbassova S.А., Apbassova M., Nuskabaeva G.О., Nurdinov N.S. Pathological changes in lung tissue under the influence of electronic cigarettes. Literature review // Nauka i Zdravookhranenie [Science & Healthcare]. 2025. Vol.27 (4), pp. 187-195. doi 10.34689/SH.2025.27.4.020Похожие публикации:
MAPPING THE RESEARCH LANDSCAPE: IONIZING RADIATION-INDUCED OXIDATIVE STRESS AND INFLAMMATION IN THE BRAIN – A BIBLIOMETRIC ANALYSIS
ASSOCIATION BETWEEN EXPOSURE TO IONIZING RADIATION AND THE DEVELOPMENT OF CARDIOVASCULAR DISEASES: A LITERATURE REVIEW
ADVANCES IN POTENTIAL BIOMARKERS FOR RHEUMATOID ARTHRITIS: SYSTEMATIC REVIEW
RISK FACTORS AND PREVALENCE OF URINARY INCONTINENCE AMONG WOMEN IN FOREIGN COUNTRIES. LITERATURE REVIEW
THE IMPACT OF SCREEN TIME ON THE HEALTH OF THE MUSCULOSKELETAL SYSTEM IN CHILDREN AND ADOLESCENTS: A SYSTEMATIC REVIEW