PRELIMINARY ANALYSIS AND ASSESSMENT OF THE HEALTH STATUS OF THE DESCENDANTS OF PERSONS EXPOSED TO RADIATION, LIVING IN THE BESKARAGAI DISTRICT OF THE ABAY REGION
Introduction: The effects of chronic low-dose ionizing radiation on human health have been the subject of scientific research for several decades. However, the long-term effects of chronic low-dose irradiation on the human body, including those of the third and subsequent generations, remain unresolved.
The aim of this study was to conduct a preliminary assessment of the health screening results of the Beskaragay district population, including second- and third-generation residents exposed to radiation from nuclear weapons testing.
Materials and Methods: A screening study of the Beskaragay district population was conducted, including questionnaires on health status, risks of developing non-communicable and socially significant diseases, and lifestyle. A preliminary analysis included 222 patients. All participants underwent a somatic assessment, as well as general clinical and biochemical analysis. Statistical analysis was performed using SPSS 20.0 (SPSS Inc., New York) and Jamovi (version 2.5.5; https://www.jamovi.org).
Results: The mean age and age distribution differed statistically between men and women (p = 0.0071), with men being more likely to be aged 40–49 years (34.5%). 63.5% of participants had lived in the area since birth (65.3%). The median systolic blood pressure in men was 130 (IQR 10) mmHg, which was significantly higher than in women (p < 0.001). 90.1% of patients had grade 1–2 thyroid enlargement. Cortisol levels were higher in men — 319.0 (122.0) nmol/L versus 249.3 (145.2) nmol/L in women (p = 0.020), while the opposite trend was observed for insulin. The median individual doses of external gamma radiation among participants were 1.8 cSv (IQR: 0.4–4.2) and did not differ statistically between men and women (p = 0.433).
Conclusions: The results of this phase of the study highlight the need for an expanded sample, in-depth clinical, laboratory, and instrumental examinations, and further registry development to study the relationship between radiation exposure and the development of somatic diseases in the offspring of exposed individuals.
Количество просмотров: 101
Категория статей:
Оригинальное исследование
Библиографическая ссылка
Kissina R.M., Pivina L.M., Chaizhunussova N.Zh., Orekhov А.Yu., Lipikhina A.V., Massabayeva M.R., Baibussinova А.ZH., Smailova Zh.K., Ygiyeva D.G., Batenova G.B., Sabitova V.R., Kozhanova S.K., Mukanova D.А., Abenova М.B., Lepesbayev М.N., Akhmadiyeva Т.A., Orazalina А.S., Apbassova S.A., Shabdarbayeva D.M., Dyussupov A.А. Preliminary analysis and assessment of the health status of the descendants of persons exposed to radiation, living in the Beskaragai district of the Abay region // Nauka i Zdravookhranenie [Science & Healthcare]. 2025. Vol.27 (5), pp. 24-31. doi 10.34689/SH.2025.27.5.003Похожие публикации:
GENETIC VARIANTS IN LIPID-ASSOCIATED GENES IN THE KAZAKHSTANI COHORT WITH ATHEROSCLEROSIS AND HYPERTRIGLYCERIDEMIA
CLONAL HEMATOPOIESIS WITH INDETERMINATE POTENTIAL IN TET2 AND DNMT3A AMONG KAZAKHSTANI INDIVIDUALS WITH ATHEROSCLEROTIC DISEASE
PRELIMINARY ANALYSIS AND ASSESSMENT OF THE HEALTH STATUS OF THE DESCENDANTS OF PERSONS EXPOSED TO RADIATION, LIVING IN THE BESKARAGAI DISTRICT OF THE ABAY REGION
PRELIMINARY ANALYSIS OF THE HEALTH STATUS AND RADIATION DOSES OF RESIDENTS OF THE ABAY DISTRICT OF THE ABAY REGION, WHO ARE DESCENDANTS OF PERSONS EXPOSED TO RADIATION DUE TO NUCLEAR WEAPONS TESTS
REPRODUCTIVE HEALTH ISSUES AMONG ADOLESCENT AND YOUNG MALE POPULATIONS. PART II