Online ISSN: 3007-0244,
Print ISSN:  2410-4280
POST-STROKE DEPRESSION: IMPACT ON ADHERENCE TO SECONDARY PREVENTION OF ISCHEMIC STROKE AND THE EFFECTIVENESS OF THERAPEUTIC INTERVENTIONS AT THE LEVEL OF PRIMARY HEALTH CARE. LITERATURE REVIEW
Introduction. Post-stroke depression (PSD) is the most common psychiatric complication following a cerebrovascular event. In every second or third patient after a stroke, slowing recovery and worsening clinical outcomes. Despite the availability of validated screening instruments, PSD remains underdiagnosed and underestimated in routine practice. Objective. To review current literature on post-stroke depression (PSD), its influence on adherence to secondary stroke prevention, and therapeutic interventions at the level of primary health care (PHC). Search strategy. This review is based on the analysis of publications addressing the impact of PSD on adherence to secondary prevention of ischemic stroke, rehabilitation processes, and clinical outcomes, as well as screening and diagnostic methods applicable in primary health care. The literature search was conducted in PubMed, Scopus, eLibrary, and Cochrane Library databases for the period 2015–2025 using the following keywords: stroke, post-stroke depression, PHQ-9, Beck Depression Inventory, primary care, screening, rehabilitation. Results. According to the literature, PSD is highly prevalent among stroke survivors. In post-Soviet countries, mental health problems remain stigmatized, leading to underrecognition and delayed diagnosis of PSD. Rehabilitation efforts are predominantly focused on motor and cognitive recovery, while depressive symptoms are often overlooked. PSD is associated with decreased treatment adherence, poorer rehabilitation outcomes, cognitive decline, and reduced quality of life. Conclusion. Early detection and a comprehensive approach to PSD management at the PHC level improve adherence to secondary prevention and rehabilitation measures. Screening programs should be expanded and systematically integrated into routine follow-up care. Timely identification and treatment of PSD improve the quality of life for patients and caregivers engaged in the rehabilitation process.
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Категория статей: Обзор литературы

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Kim Ye.D., Kondybayeva A.M., Izekenova А.K., Ospanbekova D.M., Ismailov A.K., Nurbekova G.B., Myrzakhairova A.O., Madisheva D.I. Post-stroke depression: impact on adherence to secondary prevention of ischemic stroke and the effectiveness of therapeutic interventions at the level of primary health care. Literature review // Nauka i Zdravookhranenie [Science & Healthcare]. 2025. Vol.27 (6), pp. 149-158. doi 10.34689/SH.2025.27.6.017

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