THE ROLE OF GENE AND STRUCTURAL MUTATIONS IN THE PROGRESS OF RADIATION-INDUCED MUTAGENESIS
As realized by mechanisms of carcinogenesis was achieved sufficient progress and compiled huge material that is re-flected in selected articles. On a par proto-oncogenes are low-level, their protein products in healthy cellules are participate in regulation of apoptosis processes, proliferation, cell cooperation, regulation of signaling inside the cellule. Radiation ef-fects causing the mutations one of gene allele is factor into neoplastic cellule transformation that cause chromosomal rear-rangements and proto-oncogenes amplification. Such mutations studying is represents solitary interest for radiation biology and medicine and enlarging our knowledge in the field of mutagenesis.
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