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RISK OF DISORDERS OF NONSPECIFIC RESISTANCE DUE TO LONG-TERM EXPOSURE TO RADIATION IN SMALL DOSES
Background: long-term exposure to ionizing radiation in small doses on the human body is manifested by violations of the adaptive response of regulatory systems to stress.

Aim: to perform a systematic search of valid scientific data in order to assess the disorders of nonspecific resistance in the human organism due to long-term exposure to radiation in small doses

Materials and methods. The search for scientific publications was carried out in the evidence-based medicine’s databases (PubMed, Cochrane Library, ResearchGate, Google Scholar) and in the electron...
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2017 year | Issue: 5 | Pages: 158-171

ASSESSMENT OF PSYCHOLOGICAL STATUS OF THE PEOPLE LIVING IN THE CONDITIONS OF RADIATION EXPOSURE: A SYSTEMATIC REVIEW
Background: the population residing on the territories exposed to ionizing radiation, suffer from many stressors, which creates medical and psychological tension.

Aim: to conduct a systematic search of valid scientific data in order to assess the state of psychological health of population living in ecologically unfavorable territories.

Materials and methods. The search for scientific publications was carried out in the evidence-based medicine’s databases (PubMed, Cochrane Library, TripDatabase, ResearchGate) and in the electronic scientific libraries (Cy...
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2017 year | Issue: 5 | Pages: 145-157

CONGENITAL HEART DISEASES IN CHILDREN COMPLICATED BY PULMONARY HYPERTENSION. DIAGNOSIS AND TREATMENT. LITERATURE REVIEW
Introduction. Congenital heart diseases (CHD) occupy one of the leading places in the structure of the incidence of children and adolescents. The study of congenital heart anomalies, methods of diagnosis and treatment began in the 30s of the XX century. And to date, this problem is relevant for further study, since there are still no algorythm of early diagnostic of the CHD. The most frequent and severe complication of many CHD is pulmonary hypertension, which, when untimely surgical treatment leads to disability and early infant mortality.

Purpose: To study and analyze t...
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2017 year | Issue: 5 | Pages: 129-144

MODERN APPROACHES TO RISK ASSESSMENT, MECHANISMS OF DEVELOPMENT AND PRINCIPLES OF TREATMENT FOR ARTERIAL HYPERTENSION IN CHRONIC KIDNEY DISEASE
Introduction: chronic kidney disease (CKD) is an independent risk factor for the development of circulatory diseases and cardiovascular complications. Hypertension due to nephrology diseases is the most common cause of symptomatic hypertension.

Aim: to conduct systematic research of scientific information on risk assessment, development mechanisms and principles of treatment for arterial hypertension in chronic kidney disease.

Search strategy. The search for relevant scientific publications was carried out in databases of evidence-based medicine (PubMed, ...
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2017 year | Issue: 5 | Pages: 113-128

COMMENTS ON 2017 EUROPEAN GUIDELINES FOR THE MANAGEMENT OF ACUTE MYOCARDIAL INFARCTION IN PATIENTS PRESENTING WITH ST-SEGMENT ELEVATION
Updated European guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation were published in 2017. All the new and changed recommendations was analysed in order to investigate the possibility of their application in our country.

Objective: to reveal essential evidence-based updated points of the 2017 guidelines that can be implemented in the settings of Kazakhstan health care system.

Materials and methods: the first stage of the review was performing a comparative analysis of old (2012) and updated versions ...
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2017 year | Issue: 5 | Pages: 99-112