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FACTORS, ASSOCIATED WITH ONE YEAR SURVIVAL AFTER STROKE IN KAZAKHSTAN: A COHORT STUDY
Introduction. Many unresolved question exist about the predictors of stroke outcome. The evidence on the determinants of stroke survival in Kazakhstan is very scarce, despite the high prevalence of the problem.
The aim: To study factors associated with one -year stroke survival in a population of Semey, Kazakhstan.
Methods. All cases of stroke were included in a cohort in Semey from 01.01.2014 to 31.12.15 (N = 937).Survival of patients with stroke was assessed using Kaplan-Mayer curves and log-rank tests. Independent associations of the studied factors with survival were s... More
The aim: To study factors associated with one -year stroke survival in a population of Semey, Kazakhstan.
Methods. All cases of stroke were included in a cohort in Semey from 01.01.2014 to 31.12.15 (N = 937).Survival of patients with stroke was assessed using Kaplan-Mayer curves and log-rank tests. Independent associations of the studied factors with survival were s... More
2016 year | Issue: 3 | Pages: 46-57
POLYMORPHISM OF IL10 GENE AT -1082G/A POSITION IN PATIENTS WITH ERYSIPELAS
The aim of this study is reveal the association of polymorphism of IL10 gene (rs1800896) at 1082 GA position with the erysipelas in Kazakh population.
Materials and methods. The polymorphism of IL10 gene (rs1800896) was assessed in 206 patients with erysipelas and 422 control subjects. Of them 143 patients with primary erysipelas and 63 with recurrence erysipelas. Genomic DNA was extracted from blood for genotyping. Genotyping of polymorphism of IL10 gene (-1082 GA) was conducted by method of polymerase chain reaction in real time. Pearson’s Chi tests ... More
Materials and methods. The polymorphism of IL10 gene (rs1800896) was assessed in 206 patients with erysipelas and 422 control subjects. Of them 143 patients with primary erysipelas and 63 with recurrence erysipelas. Genomic DNA was extracted from blood for genotyping. Genotyping of polymorphism of IL10 gene (-1082 GA) was conducted by method of polymerase chain reaction in real time. Pearson’s Chi tests ... More
2016 year | Issue: 3 | Pages: 34-45
ИЗМЕНЕНИЯ В ПЛАЗМЕ ТРИЙОДТИРОНИНА, ТИРОКСИНА И ТИРЕОТРОПНОГО ГОРМОНА ПОСЛЕ ОБЛУЧЕНИЯ 131 I У НОВОРОЖДЕННЫХ КРЫС, СОДЕРЖАВШИХСЯ НА ЙОДОДЕФИЦИТНОМ ПИТАНИИ
Введение: Щитовидная железа человека обычно рассматривается как орган с относительно низким риском развития пострадиационного онкогенеза. Однако резкое увеличение случаев рака щитовидной железы после аварии на Чернобыльской АЭС в 1986 году создало предпосылки к изучению факторов риска развития рака щитовидной железы. Были определены три ключевых фактора риска: (1) внутреннее облучение от 131I, (2) молодой возраст, и (3) диета с низким содержанием йода. Наше предыдущее исследование крыс различного возраста и массой тела, которые были подвержены облучению 131I ...
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2016 year | Issue: 3 | Pages: 26-33
ANALYSIS OF QUANTITATIVE DATA IN TWO NON-INDEPENDENT GROUPS USING STATISTICA AND SPSS SOFTWARE: PARAMETRIC AND NON-PARAMETRIC TESTS
In this article we present general information about Student’s paired t-test, non-parametric Wilcoxon test for paires samples and sign test which are often used for comparing paired numerical data. Algoritms for the use of all abovementioned criteria using Statistica 10 and SPSS 20 software are presented as well as recommendations on how to interpret results of the tests. This article covers basic knowledge needed for practical implementation of tests for paired observations (continuopus data) and does not substitute reading specialized literature in biostatistics and clinical epidemio...
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2016 year | Issue: 3 | Pages: 5-25
THE COMPARATIVE ANALYSIS OF DISTRIBUTION OF WORKING HOURS AT THE STAFF OF THE SURGICAL DEPARTMENT USING MEDICAL INFORMATION SYSTEM
Optimization of activity of staff of medical institutions, including surgical departments, is an integral part of reforming of health system. One of the important directions is the informatization realized by means of development and operation of medical information systems.
Research objective – the comparative analysis of distribution of working hours at the staff of surgical departments which are carrying out and not carrying out use of medical information system.
Materials and methods. Within work questioning and monitoring of working hours of 74 doctors-surgeons, including 55 –... More
Research objective – the comparative analysis of distribution of working hours at the staff of surgical departments which are carrying out and not carrying out use of medical information system.
Materials and methods. Within work questioning and monitoring of working hours of 74 doctors-surgeons, including 55 –... More
2016 year | Issue: 2 | Pages: 150-161