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EPIDEMIOLOGY OF LARYN'S CANCER IN THE REPUBLIC OF KAZAKHSTAN IN 2008-2017
Relevance. Esophageal cancer (RP), according to Global Cancer Statistics, in 2018, the total number of patients with the first-ever diagnosis was 3.2% in the overall structure of oncological diseases. Mortality from RP amounted to 5.3% in the overall structure of mortality from this disease.
The aim of the study is to analyze the incidence of esophageal cancer, mortality from this disease, as well as morbidity rates among the male and female population in the Republic of Kazakhstan (RK) for the period 2008–2017.
Materials and methods. Forms number 35 Annual,... More
The aim of the study is to analyze the incidence of esophageal cancer, mortality from this disease, as well as morbidity rates among the male and female population in the Republic of Kazakhstan (RK) for the period 2008–2017.
Materials and methods. Forms number 35 Annual,... More
2019 year | Issue: 2 | Pages: 83-90
EXPERIMENTAL ANALYSIS OF SAFETY OF ISOFLURANE LONG-TERM USE IN A CLOSED LOOP
Relevance. The main problem with the use of inhalation anesthetics in a closed loop is the interaction of halogen-containing preparations with a carbon dioxide absorber, as a result of which volatile toxic substances are released. There are several options to ensure the safety of anesthesia, one of which may be a decrease in the content of anesthetic in the gas mixture.
The purpose of the study is to experimentally test the safety hypothesis of a long-term exposure of a halogen-containing anesthetic in closed-loop mode with its low content in the respiratory mixture.
Materials and ... More
The purpose of the study is to experimentally test the safety hypothesis of a long-term exposure of a halogen-containing anesthetic in closed-loop mode with its low content in the respiratory mixture.
Materials and ... More
2019 year | Issue: 2 | Pages: 76-82
УСОВЕРШЕНСТВОВАННЫЙ МЕТОД ОДНОСТОРОННЕЙ СПИНАЛЬНОЙ АНЕСТЕЗИИ, ПРЕДВАРИТЕЛЬНЫЕ РЕЗУЛЬТАТЫ
Введение. Односторонняя, или по-другому, монолатеральная спинальная анестезия (ОСА/МСА), это один из методов обезболивания при односторонних операциях на нижних конечностях. Однако данный вид обезболивания не лишен недостатков. Одним из главных критериев при оценке данного вида анестезии является частота удачных монолатеральных блокад, которая по данным разных авторов, варьирует от 13% до 94%. Такой разброс, несомненно, не является критерием «надежного» метода анестезии и во многих случаях объясняется техникой ее выполнения. В последние годы, Мамыров Д.У. с соавторам...
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2019 year | Issue: 2 | Pages: 67-75
DANGEROUS AND UNDESIRABLE DRUG INTERACTIONS OF STATINS IN PATIENTS WITH CARDIOVASCULAR DISEASE
Relevance. Antihypercholesterolemic drugs fr om the group of statins have a significant impact on the metabolism of the human body. Consideration of pharmacokinetic features of statins and drug interaction with drugs of this group is an important aspect of their safe use. Drugs administered simultaneously with statins may be inducers or inhibitors (substrates) of CYP3A4/A5 cytochrome P450 liver isoenzymes, which should be considered in daily clinical practice in the management of this category of patients
The aim was to study the frequency and structure of the appointment of unw... More
The aim was to study the frequency and structure of the appointment of unw... More
2019 year | Issue: 2 | Pages: 55-66
PREVALENCE OF ATRIAL FIBRILLATION AND ITS CORRELATES IN HYPERTENSIVE PATIENTS WITHOUT CORONARY HEART DISEASE IN PRIMARY CARE SETTING
Hypertension is a risk factor for atrial fibrillation (AF). Primary prevention of AF in hypertension patients is the ultimate goal of the medical and public health community.
Aim: assess the prevalence and factors associated with AF in hypertensive patients without coronary heart disease (CHD) in primary care setting.
Methods: A cross–sectional study was conducted in January-September 2018. Hypertensive patients 40 years and above visiting primary care clinics during the study period were recruited (n=1121). Exclusion criteria were rheumatic and congenital h... More
Aim: assess the prevalence and factors associated with AF in hypertensive patients without coronary heart disease (CHD) in primary care setting.
Methods: A cross–sectional study was conducted in January-September 2018. Hypertensive patients 40 years and above visiting primary care clinics during the study period were recruited (n=1121). Exclusion criteria were rheumatic and congenital h... More
2019 year | Issue: 2 | Pages: 44-54