Online ISSN: 3007-0244,
Print ISSN:  2410-4280


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OPTIMIZATION OF TREATMENT TACTICS FOR ATHEROSCLEROTIC LESIONS IN THE FEMOROPOPLITEAL SEGMENT

Introduction: One of the most frequent localizations of arterial occlusive diseases leading to the loss of the limb is the femoropopliteal segment. In the treatment of arterial lesions in the femoropopliteal segment, surgical methods of treatment (shunting and endovascular methods of treatment) are used in most cases. If it is not possible to conduct direct revascularization operations, this category of patients has a high risk of limb amputation at the hip level. In case of femoropopliteal occlusion, the viability of the limb d...

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2018 year | Issue: 3 | Pages: 60-73

DIFFERENTIATED TACTICS OF TREATMENT OF COLON CANCER COMPLICATED BY PERFORATION, INCLUDING THE RISK OF COLON AND ENTEROCOLIC ANASTOMOSES FAILURE

Introduction. In recent decades, the worldwide increase in the incidence of colorectal cancer (further on CRC) is noted. A serious complication of CRC is perforation of the tumor or rupture of the intestinal wall proximal to the neoplasm. Prospects for improving the results of treatment of complicated colorectal cancer require the definition of conditions and the creation of an optimal algorithm for using surgical techniques of restoring the intestinal passage in combination with a complex pathogenetic approach, restoring the di...

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2018 year | Issue: 3 | Pages: 45-59

EPIDEMIOLOGY OF PROSTATE CANCER IN SEMEY REGION OF EAST KAZAKHSTAN REGION

Background: prostate cancer holds second position out of all cancer morbidity among the world male population. At the same time, taking into account the female population, incidence of prostate cancer is on the fourth place, yielding its position to lung cancer, breast cancer and colorectal cancer. Prostate cancer is most common in the developed world, for which long life expectancy is characteristic, but it is less common in Asian countries, where it locates in the sixth place after cancers of other localizations: lung, stomach, liver, colorectal cancer ...

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2018 year | Issue: 3 | Pages: 32-44

CHRONOMODULATED APPROACH TO CHEMORADIOTHERAPY OF LOCALLY ADVANCED HEAD AND NECK CANCER

Introduction. The standard treatment for patients with inoperable locally advanced head and neck cancer is chemoradiotherapy with cisplatin. The high toxicity of this method doesn’t allow it to be used with 30,0 % of patients, namely patients older than 70 years, with low somatic status. One of the ways to increase the efficiency and reduce toxicity is the use of chemomodifiers in the chronomodulated mode in combination with non-standard dose fractionation regimes.

The aim of the study. To analyze the effectiveness of different methods...

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2018 year | Issue: 3 | Pages: 20-31

MORPHOMЕTRІC ІNDІCATORS OF THЕ SMALL ІNTЕSTІNЕ OF ІRRADІATЕD RATS

Іntrоductіоn. Іtʹs knоwn that реrsоns еxроsеd tо β− and γ–raуs, tоgеthеr wіth a dіffеrеnt оf damagіng еffеcts, рartіcular іmроrtancе іs alsо attachеd tо thе dіgеstіvе sуstеm. Thе dоmіnant rоlе оf nеutrоn−actіvatеd radіоnuclіdе Manganеsе−56 (56Mn) was nоtеd іn thе trеatіsеs оf scіеntіsts whо studіеd thе atomіc bоmb еffеcts оf Japanеsе cіtіеs, dеsеrvіng thе іntеrеst tоdaу.

Thе rеsеarch рurроsе. Іnvеstіgatе and comparе thе morphomеtrіc іndіcators іn thе small іntеstіnе оf rats еxроsеd tо low dosе bу β– and γ–raуs.

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2018 year | Issue: 3 | Pages: 5-19