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WAYS OF IMPROVING THE QUALITY AND ENHANCING THE ECONOMIC EFFICIENCY OF NATIONAL SCREENING PROGRAM FOR THE EARLY DETECTION OF ONCOLOGICAL DISEASES (FOR EXAMPLE PAVLODAR REGION). STUDY PROTOCOL.
Introduction. In Kazakhstan, the national screening program for the early detection of diseases was introduced in 2011. It is noted the low efficiency of the National screening program, the effectiveness of screening is not monitored on the basis of the recommendations on the effectiveness of early detection of cancer and their successful treatment.
Methods / design. The purpose of this study: to develop measures to improve results and increase cost-effectiveness of national screening program for early detection of oncological diseases. Studied nosologies: cervical cancer, breast ... More
Methods / design. The purpose of this study: to develop measures to improve results and increase cost-effectiveness of national screening program for early detection of oncological diseases. Studied nosologies: cervical cancer, breast ... More
2017 year | Issue: 1 | Pages: 97-111
VIDEO ENDOSCOPE TECHNOLOGY WITH MINIMALLY INVASIVE SURGICAL TREATMENT OF PATIENTS WITH CORONARY HEART DISEASE: CASE SERIES REPORT
Coronary artery bypass surgery with using endoscopic technology is the most recent trend of surgical treatment of coronary heart disease.
The purpose of this work is to present the experience of the 8 video assistant cardiac surgery in a "Pavlodar Regional Cardiological Center" for the period from 2012 to 2016.
Materials and methods. Design - case series. All 8 patients underwent minimal-ivasive direct coronary artery bypass off pump, with endoscopic release of the left internal mammary artery (LIMA), and making anastomosis LIMA to left anterior desc... More
The purpose of this work is to present the experience of the 8 video assistant cardiac surgery in a "Pavlodar Regional Cardiological Center" for the period from 2012 to 2016.
Materials and methods. Design - case series. All 8 patients underwent minimal-ivasive direct coronary artery bypass off pump, with endoscopic release of the left internal mammary artery (LIMA), and making anastomosis LIMA to left anterior desc... More
2017 year | Issue: 1 | Pages: 87-96
COMMENTS ON 2016 EUROPEAN GUIDELINES FOR THE MANAGEMENT OF ATRIAL FIBRILLATION: NEW ASPECTS FOR PHYSICIANS
Updated European guidelines for the management of atrial fibrillation were published on the 27 of August, 2016. This document is remarkable for new recommendations, especially about anticoagulation therapy. Key points of these guidelines and the possibility of their use in our country are described in the article.
Objective: to find out essential evidence-based key points of the 2016 guidelines and to investigate the possibility of their use in Kazakhstan.
Materials and methods: To achieve these goals major differences between 2016, 2012, 2010 guidelines were analyze... More
Objective: to find out essential evidence-based key points of the 2016 guidelines and to investigate the possibility of their use in Kazakhstan.
Materials and methods: To achieve these goals major differences between 2016, 2012, 2010 guidelines were analyze... More
2017 year | Issue: 1 | Pages: 74-86
IMMUNOHISTOCHEMICAL ANALYSIS EXPRESSION TP73 IN ONCOCYTIC FOLLICULAR ADENOMA OF THE THYROID
Oncocytic follicular adenomas (FAs) of the thyroid are cells neoplasms of follicular origin that predominantly consist of large polygonal cells with eosinophilic and granular cytoplasm. According to some scientific studies, TP73 might play a сertain role in tumor genesis (oncogenesis). Moreover, due to the absence of p53, oncogenes may attract p73 to induce apoptosis in tumor cells. TP53 is a crucial tumor suppressor in preventing the cancerous transformation of cells. There was also a particular focus on the amplification of 1p36 chromosome in oncocytic FA, which contains a t...
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2017 year | Issue: 1 | Pages: 64-73
ASSESSMENT OF TOXICITY OF NEOADJUVANT CHEMOTHERAPY FOR LOCALLY ADVANCED BREAST CANCER
Introduction. In the structure of malignancies in women breast cancer (BC) takes 1st place. In locally advanced breast cancer (LABC) treatment begins with neoadjuvant chemotherapy (CTX), the standard protocols are CMF, FAC, AC. In the trial, we used cytostatic Arglabin isolated from plants endemic to Central Kazakhstan - wormwood smooth, as monotherapy and as addition to AC-protocol.
The objective of the trial - to assess the toxicity of different protocols of neoadjuvant CTX of LABC.
Methods: 93 patients with LABC (T2N1-2M0, T3N0-2M0) ... More
The objective of the trial - to assess the toxicity of different protocols of neoadjuvant CTX of LABC.
Methods: 93 patients with LABC (T2N1-2M0, T3N0-2M0) ... More
2017 year | Issue: 1 | Pages: 52-63