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                            ROLE OF ACADEMICIAN V.A. NASONOVA IN DEVELOPMENT OF RHEUMATOLOGY OF KAZAKHSTAN
                        
            
                
                
                    
            
            
        
                    
                
                This article presents history of rheumatology of Kazakhstan and Semipalatinsk, the role of academician Nasonova V.A for new directions of development of Kazakhstan rheumatology and research scientific school of Professor Ivanova R.L.                
                                    
                                
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                                                    2018 year                                                                            | Issue: 5                                                                            | Pages: 172-175                                            
                
                            THE PREVALENCE OF POLYMORPHISMS OF SOME GENES ASSOCIATED WITH THE FUNCTION OF PLASMA-PLATELET HEMOSTASIS, WITH ASPIRIN RESISTANCE  IN THE KAZAKH POPULATION
                        
            
                
                
                    
            
            
        
                    
                
                The relevance of the research topic: Aspirin is the most common antiplatelet drug in world clinical practice. It is a first-line agent in the treatment of acute forms of vascular insufficiency associated with atherosclerosis of the arteries. In addition, along with antihypercholesterol drugs, aspirin is most often used for primary and secondary prevention of these conditions. A rather common condition in a population is a decrease in the effectiveness of aspirin, defined by the term «aspirin resistance». The main cause of aspirin resistance is considered to be the genetic characteristics of pa...                
                                    
                                
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                                                    2018 year                                                                            | Issue: 5                                                                            | Pages: 164-171                                            
                
                            NATIONAL EXPERTISE CENTER BRANCHES AND DEPARTMENTS OF PUBLIC HEALTH PROTECTION COMMITTEE SPECIALISTS OPINIONS ABOUT THE ACTIVITIES AND STATUS OF SANITARY  AND EPIDEMIOLOGICAL EXPERTISE ORGANIZATION
                        
            
                
                
                    
            
            
        
                    
                
                Background. The Sanitary and Epidemiological Expertise Institutions - the branches of the RSE the National Expertise Center (hereinafter referred to as the NEC) of the Republic of Kazakhstan Ministry of Health, Public Health Protection Committee (hereinafter referred to as the RK MoH, PHPC) execute laboratory research in the field of ensuring the state guarantees to the citizens of the Republic of Kazakhstan for sanitary, epidemiological, ecological well-being and radiation safety [11]. The main customers of laboratory control within the SSES (State Sanitary and Epidemiological Surveillance) a...                
                                    
                                
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                                                    2018 year                                                                            | Issue: 5                                                                            | Pages: 153-163                                            
                
                            CONGENITAL HEART DISEASES AND CONNECTIVE TISSUE DYSPLASIA CHILDREN OF SEMEY, THE DETERMINATION THE FREQUENCY
                        
            
                
                
                    
            
            
        
                    
                
                Introduction. The community of pathogenetic mechanisms of congenital heart diseases  and connective tissue dysplasia connective tissue dysplasia defines increase in risk of their combinations. At the same time perhaps essential deterioration in the forecast of a current and conditions for correction of connective tissue dysplasia. So far poorly studied are an actual frequency and structure of combinations of these pathological states in population. 
Research objective – to determine the frequency of signs connective tissue dysplasia in children with connective tissue dysplasia are living in S...                
                                    
                                
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                                                    2018 year                                                                            | Issue: 5                                                                            | Pages: 145-152                                            
                
                            FACTORS OF ADDICTIVE PREDISPOSITION AMONG FIRST-YEAR STUDENTS OF SEMEY STATE MEDICAL UNIVERSITY
                        
            
                
                
                    
            
            
        
    
            
    
                
                Introduction: Training in a medical university is associated with a tense adaptation, which leads to a change in the mental status of students. This may result in vulnerability to addictions and the possible development of dependent behavior.
The aim of the study was to determine the prevalence of the addiction risk in students of the Semey State Medical University of (SSMU), as well as in the context of interrelated socio-psychological factors.
Materials and methods: A one-stage cross-sectional evaluation was carried out using a questionnaire of 643 first-year students of the Semey State Me...                
                                    
                                
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                                                    2018 year                                                                            | Issue: 5                                                                            | Pages: 135-144                                            
                