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CLINICAL AND MORPHOLOGICAL FEATURES OF BREAST CANCER AMONG WOMEN WITH RADIOECOLOGICAL AND FAMILY ANAMNESIS
The peculiarities of histomorphological characteristics of malignant neoplasm can be linked to its genesis, including the presence of genetic changes in regulatory genes. By-turn, the frequency of the last depends from the influence of mutagenic factors.
The aim. The purpose of research is to determine the morphological features of breast cancer due to the presence of gene mutations BRCА1 and TP53 among women with family and radioecological anamnesis.
Materials and methods. The study included 190 women aged between 40 to 78 years, patients with breast cancer, ethnic Kazakhs, alloc... More
The aim. The purpose of research is to determine the morphological features of breast cancer due to the presence of gene mutations BRCА1 and TP53 among women with family and radioecological anamnesis.
Materials and methods. The study included 190 women aged between 40 to 78 years, patients with breast cancer, ethnic Kazakhs, alloc... More
2016 year | Issue: 1 | Pages: 66-76
MINERALIZATION OF THE PERITONEUM IN PERITONEAL CARCINOMATOSIS
Conducted assessment of sero-lymphatic hatches and submesothelial relief structures of the parietal peritoneum in peritoneal carcinomatosis. The object of study of autopsy material from deceased neglected forms of malignant neoplasms 2012-2015. We believe that the data obtained will make a significant contribution to the theory of cancer metastasis.
The purpose of the study. To assess the serous-lymphatic hatches (SLH) diaphragmatic and pelvic peritoneum cancer with the phenomenon of PC and to examine their role in the pathogenesis of dissemination of cancer cells on the peritone... More
The purpose of the study. To assess the serous-lymphatic hatches (SLH) diaphragmatic and pelvic peritoneum cancer with the phenomenon of PC and to examine their role in the pathogenesis of dissemination of cancer cells on the peritone... More
2016 year | Issue: 1 | Pages: 54-65
COMPARATIVE EVALUATION OF CHOLECYSTECTOMY TECHNIQUES
Introduction: The review compares the efficacy and safety of mini-laporatomy, laparoscopy and traditional cholecystectomy. We summarizes results of studies on advantages and disadvantages of various methods of cholecystectomy with considering of after-operational complications, mortality, average residence of patients in hospital and rehabilitation period.
The aim: to summarize and compare modern cholecystectomy techniques.
Materials and methods: Systematic review and subsequent analysis of publication data and online sources were carried outusing PubMed, MEDLINE, books, publicati... More
The aim: to summarize and compare modern cholecystectomy techniques.
Materials and methods: Systematic review and subsequent analysis of publication data and online sources were carried outusing PubMed, MEDLINE, books, publicati... More
2016 year | Issue: 1 | Pages: 40-53
АTHEROGENESIS AND INFLAMMATION
Introduction: The article presents atherosclerosis theory and modern views on the role of inflammation in atherogenesis. We reviewed national and international literature on inflammatory theory of atherosclerosis, the role of cytokines in the development of atherosclerosis, the interaction of the lipid and inflammatory theory of atherogenesis, the formation of atherosclerotic plaque. Basic research in molecular biology, immunology, genetics have greatly expanded the concept of the pathogenesis of atherosclerosis.
The aim: Сonducting a literature review on the pathogenesis of atheroscler... More
The aim: Сonducting a literature review on the pathogenesis of atheroscler... More
2016 year | Issue: 1 | Pages: 24-39
DESCRIPTIVE STATISTICS USING STATISTICA AND SPSS SOFTWARE
This is the first paper of a series of articles where we describe basic principles of statistical data analysis using Statistica and SPSS software for beginners. Step-be-step algorithms for presentation of quantitative and qualitative data including normality testing are presented. Measures of central tendency and variability are explained and practical examples using the data from earlier studies are given. The main aim of this paper is to provide basic knowledge on descriptive statistics with practical examples using popular software. The article complements, but does not substitute speciali...
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2016 year | Issue: 1 | Pages: 7-23