Online ISSN: 3007-0244,
Print ISSN:  2410-4280
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EPIDEMIOLOGY OF LARYN'S CANCER IN KAZAKHSTAN IN 2008–2017
Relevance. Laryngeal cancer (LC) remains one of the most common respiratory tract tumors and makes up from 2 to 4% of all malignant tumors. In 2016, 13,430 new cases of RH were diagnosed, with approximately 3,620 patients dying from this disease.
Objective: to conduct an epidemiological assessment of morbidity, mortality, five-year survival in the WG in the Republic of Kazakhstan (RK) for the period 2008–2017, as well as indicators of early detection of this malignant neoplasm.
Materials and methods. The analysis of the incidence of laryngeal cancer, mortality f...
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2019 year | Issue: 2 | Pages: 91-97

EPIDEMIOLOGY OF LARYN'S CANCER IN THE REPUBLIC OF KAZAKHSTAN IN 2008-2017
Relevance. Esophageal cancer (RP), according to Global Cancer Statistics, in 2018, the total number of patients with the first-ever diagnosis was 3.2% in the overall structure of oncological diseases. Mortality from RP amounted to 5.3% in the overall structure of mortality from this disease.
The aim of the study is to analyze the incidence of esophageal cancer, mortality from this disease, as well as morbidity rates among the male and female population in the Republic of Kazakhstan (RK) for the period 2008–2017.
Materials and methods. Forms number 35 Annual,...
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2019 year | Issue: 2 | Pages: 83-90

EXPERIMENTAL ANALYSIS OF SAFETY OF ISOFLURANE LONG-TERM USE IN A CLOSED LOOP
Author(s): Tanatarov S.Z
Relevance. The main problem with the use of inhalation anesthetics in a closed loop is the interaction of halogen-containing preparations with a carbon dioxide absorber, as a result of which volatile toxic substances are released. There are several options to ensure the safety of anesthesia, one of which may be a decrease in the content of anesthetic in the gas mixture.
The purpose of the study is to experimentally test the safety hypothesis of a long-term exposure of a halogen-containing anesthetic in closed-loop mode with its low content in the respiratory mixture.
Materials and ...
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2019 year | Issue: 2 | Pages: 76-82

УСОВЕРШЕНСТВОВАННЫЙ МЕТОД ОДНОСТОРОННЕЙ СПИНАЛЬНОЙ АНЕСТЕЗИИ, ПРЕДВАРИТЕЛЬНЫЕ РЕЗУЛЬТАТЫ
Введение. Односторонняя, или по-другому, монолатеральная спинальная анестезия (ОСА/МСА), это один из методов обезболивания при односторонних операциях на нижних конечностях. Однако данный вид обезболивания не лишен недостатков. Одним из главных критериев при оценке данного вида анестезии является частота удачных монолатеральных блокад, которая по данным разных авторов, варьирует от 13% до 94%. Такой разброс, несомненно, не является критерием «надежного» метода анестезии и во многих случаях объясняется техникой ее выполнения.  В последние годы, Мамыров Д.У. с соавторам...
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2019 year | Issue: 2 | Pages: 67-75

DANGEROUS AND UNDESIRABLE DRUG INTERACTIONS OF STATINS IN PATIENTS WITH CARDIOVASCULAR DISEASE
Relevance. Antihypercholesterolemic drugs fr om the group of statins have a significant impact on the metabolism of the human body. Consideration of pharmacokinetic features of statins and drug interaction with drugs of this group is an important aspect of their safe use. Drugs administered simultaneously with statins may be inducers or inhibitors (substrates) of CYP3A4/A5 cytochrome P450 liver isoenzymes, which should be considered in daily clinical practice in the management of this category of patients
The aim was to study the frequency and structure of the appointment of unw...
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2019 year | Issue: 2 | Pages: 55-66