Background: The objective of this retrospective study was to determine the place of MPV and NLR in the assessment of the mortality within the first three months in patients, who were diagnosed with an acute cerebrovascular disease (ACD). Methods: The patients who were hospitalized in the neurology service from our emergency service between the dates 01.01.2014 and 31.12.2014 were assessed retrospectively. The patients, who were followed up for 3 months, were divided into two groups as survived (Group 1) and exitus (Group 2). Mann-Whitney U test was used for statistically analysis. p<0.05 was accepted as significantly. Results: The median MPV value was found that 10.30 (1,1) fL in group1 and 10.20 (0.8) fL in group 2. The median NLR value was found that 2.40 (2.2) fL in group1 and 2.86 (1.7) fL in group 2. There was no statistically significant difference between two groups for MPV and NLR. Conclusion: We conclude that MPV and NLR did not have a role in the determination of the early mortality in stroke patients.
Ertugrul Altinbilek1, Derya Ozturk1, Abdullah Algın2, Cilem Caltili1, Mustafa Calik3, Balkan Sahin1, Gulsum Kavalci4, Cemil Kavalci5 1 Şişli Etfal Training and Research Hospital, Emergency Department, İstanbul/Turkey; 2 Umranniye Training and Research Hospital, Emergency Department, İstanbul/Turkey; 3 Gazi Osmanpaşa Training and Research Hospital, Emergency Department, İstanbul/Turkey; 4 Yenimahalle Training and Research Hospital, Anesthesia Department, Ankara/Turkey; 5 Diskapi Yildirim Beyazit Training and Research Hospital, Emergency Department, Ankara/Turkey.
1. Bath P.M., Butterworth R.J. Platelet size: measurement, physiology and vascular disease. Blood Coagul Fibrinolysis. 1996; 7(2): 157-61. 2. Duman A., Dagli B., Turkdogan K.A., Kapci M., Kuruoz G., Akoz A. Diagnosis of pulmonary embolism in patients mean platelet volume, neutrophil / lymphocyte ratio and platelet / lymphocyte ratio 's foresight. Medicine Science 2016; 5(4): 1002-4. 3. Go S., Worman D.J. Stroke Syndromes. In: Tintinalli JE (eds). Tintinalli’s Emergency Medicine. A Comprehensive Study Guide. 8th ed. McGraw-Hill;2016: NY, p.1142-1155 4. Gokhan S., Ozhasenekler A., Mansur Durgun H., Akil E., Ustündag M., Orak M. Neutrophil lymphocyte ratios in stroke subtypes and transient ischemic attack. Eur Rev Med Pharmacol Sci. 2013;17(5):653-7. 5. Goyal N., Tsivgoulis G., Chang J.J., Malhotra K., Pandhi A., Ishfaq M.F. et al. Admission Neutrophil-to-Lymphocyte Ratio as a Prognostic Biomarker of Outcomes in Large Vessel Occlusion Strokes. Stroke 2018 ;49(8):1985-1987. 6. Horne B.D., Anderson J.L., John J.M., Weaver A., Bair T.L., Jensen K.R., et al. Intermountain Heart Collaborative Study Group Which white blood cell subtypes predict increased cardiovascular risk? J Am Coll Cardiol 2005; 45:1638–1643 7. Karabacak M., Dogan A., Turkdogan A.K., Kapci M., Duman A., Akpinar O. Mean platelet volume is increased in patients with hypertensive crises. Platelets. 2014;25(6):423-6. 8. Karabacak M., Varol E., Turkdogan K.A., Duman A., Akpinar O., Karabacak P. Mean Platelet Volume in Patients With Carbon Monoxide Poisoning. Angiology 2014; 65(3:) 252-6. 9. Kocaturk O., Besli F., Gungoren F., Kocaturk M., Tanriverdi Z. The relationship among neutrophil to lymphocyte ratio, stroke territory, and 3-month mortality in patients with acute ischemic stroke. Neurological Sciences 2019;40:139–146 10. Lewandowski C., Barsan W. Treatment of acute ischemic stroke. Ann Emerg Med. 2001; 37: 202-16. 11. Libby P., Ridker P.M., Maseri A. Inflammation and atherosclerosis. Circulation 2002; 105:1135–1143 12. Mathers C.D., Ma Fat D., Boerma J.T. The Global Burden of Disease: 2004 Update. Geneva, World Health Organization, 2008. Available from. last access date:08.11.2019 13. Park Y., Schoene N., Harris W. Mean platelet volume as an indicator of platelet activation: methodolojical issues. Platelets. 2002; 13(5-6): 301-6. 14. Tokgoz S., Kayrak M., Akpinar Z., Seyithanoğlu A., Güney F., Yürüten B. Neutrophil lymphocyte ratio as a predictor of stroke. J Stroke Cerebrovasc Dis 2013; 22:1169–1174 15. Xue J., Huang W., Chen X., Li Q., Cai Z., Yu T., Shao B. Neutrophil-to-lymphocyte ratio is a prognostic marker in acute ischemic stroke. J Stroke Cerebrovasc Dis 2017;26(3):650–657 16. Whisnant J.P., Basford J.R., Bernstein E.F., Cooper E.S., Dyken M.L., Easton J.D., et al. Special Report From The National Institute of Neurological Disorders and Stroke. Classification of Cerebrovascular Diseases III. Stroke. 1990; 21: 637-76. 17. Yigit M., Sogut O., Yigit E., Turkdogan K.A., Kaplan O., Dur A., et al. The relationship between anemia and recurrence of ischemic stroke in patients with Trousseau's syndrome: A retrospective cross-sectional study. Turk J Emerg Med. 2016; 16(2): 65-8. 18. Yu S., Arima H., Bertmar C., Clarke S., Herkes G., Krause M. Neutrophil to lymphocyte ratio and early clinical outcomes in patients with acute ischemic stroke. J Neurol Sci. 2018;387:115-118. doi: 10.1016/j.jns.2018.02.002.
Количество просмотров: 296

Ключевые слова:

Библиографическая ссылка

Altinbilek Ertugrul, Ozturk Derya, Algın Abdullah, Caltili Cilem, Calik Mustafa, Sahin Balkan, Kavalci Gulsum, Kavalci Cemil Роль среднего объема тромбоцитов и определение соотношения нейтрофильных лимфоцитов. Ранняя смертность у больных инсультом // Наука и Здравоохранение. 2019. 6 (Т.21). С. 30-33.