RISK MANAGEMENT AND PREVALENCE OF ARTERIAL HYPERTENSION IN A COHORT OF PEOPLE LIVING IN THE AFFECTED AREA OF RADIOACTIVE WASTE STORAGE
Relevance: The Republic of Kazakhstan occupies a leading place in the world in terms of uranium ore reserves, where about 25% of the world's proven uranium reserves are concentrated. Currently, more than 200 million tons of radioactive waste has accumulated on the territory of the Republic in the form of tailings from concentration plants, heap leaching piles, tailing dumps of hydrometallurgical plants, dumps of poor and unprocessed marketable ore, which are very dangerous as a source of radioactive and chemical pollution of the environment. Currently, there are several radioactive waste tailings in use in the republic. The largest of them is the tailing dump of radioactive waste of the Hydrometallurgical Plant of the Stepnogorsk Mining and Chemical Combine which has been operating since 1956. The plant is one of the largest complexes for the production of uranium oxide and other rare metals. The main types of industrial waste are the tailings of uranium ore processing, which, in terms of the content of radionuclides, are classified as hazard class I. Its mining undoubtedly causes an increase in uranium production and an increase in the complex of technogenic radiation and toxic effects. At the same time, an urgent issue is the assessment of the impact of low doses of ionizing radiation on the population living in the zone of impact of technogenic factors of the radioactive wastestorage of uranium processing enterprises, and the study of the risk of somatic morbidity. Aim: to assess the possible impact of technogenic factors of the storage of radioactive waste of a uranium processing enterprise on the risk and prevalence of arterial hypertension in the population. Materials and methods: The results of a cohort retrospective study over three years among persons exposed to long-term exposure to negative technogenic factors on the frequency and risk of developing somatic diseases in the main group - the population living near the storage of radioactive waste of uranium production, as well as the control group – the population of the city of Akkol located more than 100 km from the city of Stepnogorsk constituting the control group. The study covers 399 people, including 255 people in the main group and 174 people in the control group. The results of the study were processed using the IBM SPSS Statistics 20 software product and the Microsoft Excel program. Statistical calculations were carried out using the sanitary statistics method. Results: Studies have shown that long-term exposure to low doses can lead to an increase in somatic morbidity. The most characteristic for people living near radioactive waste storage facilities is the pathology of the cardiovascular system, in the structure of which the first rank is occupied by arterial hypertension – 83%, which indicates the possible influence of small doses of ionizing radiation on the risk and prevalence of arterial hypertension in the population. Conclusions: The data obtained show that long-term residence of the population in this territory has a significant impact on the prevalence of arterial hypertension.
Kuralay B. Ilbekova 1, https://orcid.org/0000-0001-9950-9808 Dujcebai D. Dzhanabayev 1, https://orcid.org/000-0001-8051-6637 Polat K. Kazymbet 1, https://orcid.org/0000-0003-3091-1721 Moldir N. Aumalikova 1, https://orcid.org/0000-0002-4242-9193 Meirat M. Bakhtin 1, https://orcid.org/0000-0001-6117-5101 Danara S. Ibrayeva 1, https://orcid.org/0000-0002-1640-1728 1 Institute of Radiobiology and radiation protection nCJSC "Astana Medical University", Nur-Sultan city, Republic of Kazakhstan.
1. Аклеев А.В., Киселев М.Ф. Медико-биологические и экологические последствия радиоактивного загрязнения реки Теча // Медицинская радиология и радиационная безопасность 2001. С.196-197. 2. Дюсембаева Н.К., Шпаков А.Е., Рыбалкина Д.Х., Салимбаева Б.М., Дробченко Е.А., Уресаев А.О. Состояние здоровья населения радиоактивно-загрязненных территорий // Гигиена труда и медицинская экология. 2016. №4 (53). С.8-9. 3. Заборовский Г.И., Барцевич И.Г. Соотношение заболеваемости, инвалидности и смертности вследствие болезней системы кровообращения // Журнал ГрГМУ. 2010. №4. С.36-37. 4. Ibrayeva D., Bakhtin M., Kashkinbayev Y., Kazymbet P., Zhumadilov K., Altaeva N., Aumalikova M., Shishkina E. Radiation situation in the territories affected by mining activities in Stepnogorsk areas, Republic of Kazakhstan: pilot study // Radiation protection dosimetry, 2020, 189(4), С. 517-526. 5. Кашкинбаев Е.Т., Сайфулина Е.А., Скаков М.Ж., Токлаева С.А., Хусаин Ш.К., Бахтин М.М., Казымбет П.К. Распространенность заболеваний у населения, проживающего в зоне влияния хранилищ радиоактивных отходов. Валеология денсаулық - ауру - сауықтыру 2018. №4. С.139-140. 6. Куруптурсунов А.А. Анализ заболеваемости населения Саратовской области болезнями системы кровообращения // Бюллетень Медицинских Конференций. 2012. Т.2. №11. С.2-3. 7. Карпов А.Б., Семенов Ю.В., Литвиненко Т.М. и соавт. Сердечно-сосудистая система и ионизирующее излучение. Ч. I. Острый инфаркт миокарда // Под общ. ред. Р.М. Тахауова. – Томск: Изд-во Том. ун-та, 2009. С. 175-179. 8. Фролова Е.В. Артериальная гипертензия // Russian Family Doctor. 2016. 20 (2). С. 6-18. References: 1. Akleev A.V., Kiselev M.F. Mediko-biologicheskie i ekologicheskie posledstviya radioaktivnogo zagryazneniya reki Techa [Biomedical and environmental effects of radioactive contamination of the Techa River]. Meditsinskaya radiologiya i radiatsionnaya bezopasnost 2001. pp. 196-197 [in Russian]. 2. Dyusembaeva N.K., Shpakov A.E., Rybalkina D.Kh., Salimbaeva B.M., Drobchenko E.A., Uresaev A.O. Sostoyanye zdorovya naseleniya radioaktıvno-zagryaznennykh territorii [The health status of the population of radioactively contaminated territories]. Occupational health and medical ecology. 2016. №4 (53), pp.8-9 [in Russian]. 3. Zaborovsky G.I., Bartsevich I.G. Sootnoshenie zabolevaemosti, invalidnosti i smertnosti vsledstvie boleznej sistemy krovoobrashcheniya [The ratio of morbidity, disability and mortality due to diseases of the circulatory system]. Journal of GrGMU. 2010 №4. рр 36-37 [in Russian]. 4. Ibrayeva D., Bakhtin M., Kashkinbayev Y., Kazymbet P., Zhumadilov K., Altaeva N., Aumalikova M., Shishkina E. Radiation situation in the territories affected by mining activities in Stepnogorsk areas, Republic of Kazakhstan: pilot study// Radiation protection dosimetry, 2020, 189(4), рр. 517-526. 5. Kashkinbaev E.T., Sayfulina E.A., Skakov M.Zh., Toklaeva S.A., Khusain Sh.K., Bakhtin M.M., Kazymbet P.K. Rasprostranennost' zabolevanii u naseleniya, prozhivayushchego v zone vliyaniya hranilishch radioaktivnyh otkhodov [The prevalence of diseases in the population living in the zone of influence of radioactive waste storage]. [Valeology-health-disease-recovery], 2018. №4, pp.139-140 [in Russian]. 6. Kuruptursunov A.A. Analiz zabolevaemosti naseleniya Saratovskoj oblasti boleznyami sistemy krovoobrashcheniya [Analysis of the morbidity of the population of the Saratov region by circulatory system diseases]. Byulleten' meditsinskikh konferentsii [Bulletin of Medical Conferences]. 2012. №11. pp. 2-3 [in Russian]. 7. Karpov A.B., Semenov Yu.V., Litvinenko T.M., Ed. Takhauova R.M. Serdechno-sosudistaya sistema i ioniziruyushchee izluchenie. Ch. I. Ostryi infarkt miokarda. [Cardiovascular system and ionizing radiation. Part I. Acute myocardial infarction]. Tomsk: Publishing house of Tomsk university, 2009. pp. 175-179 [in Russian]. 8. Frolova E.V. Arterial'naya gipertenziya [Hypertension] Russian Family Doctor. 2016. 20 (2). С. 6-18 [in Russian].
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Ilbekova K.B., Dzhanabayev D.D., Kazymbet P.K., Aumalikova M.N., Bakhtin M.M., Ibrayeva D.S. Risk management and prevalence of arterial hypertension in a cohort of people living in the affected area of radioactive waste storage // Nauka i Zdravookhranenie [Science & Healthcare]. 2020, (Vol.22) 5, pp. 109-115. doi 10.34689/SH.2020.22.5.011