ASSESSMENT OF THE IMPACT OF MEDICAL AND SOCIAL FACTORS ON THE QUALITY OF LIFE OF PATIENTS WITH MALIGNANT NEOPLASMS OF THE BLOOD SYSTEM
Introduction. Cancer is the second most common cause of death worldwide. Likewise, in Kazakhstan, it is a major health problem, and disease burden is escalating every year. Cancer chemotherapy produces unfavorable effects on the well-being of an individual. Since the past few years, quality of life (QoL) has been considered as the main goal of cancer treatment in the survival of a patient.
Objective: This study aimed to evaluate the QoL of patients with malignant neoplasms of the blood system and their factors, and to explore the factors associated with QoL of patients.
Material and methods: In this cross-sectional study spanning January to March 2023, we enrolled adult blood cancer patients from the Abay and East Kazakhstan regions, assessing the QoL in 199 individuals with malignant neoplasms of the blood system. The 36-item Short-Form Health Survey (SF-36) served as the assessment tool for QOL. Statistical analyses, including independent-samples t-tests and one-way analysis of variance, were employed to compare QOL subscale scores among groups with diverse sociodemographic and clinical characteristics. Additionally, multiple regression analysis was conducted to identify factors associated with the QOL of patients and their determinants.
Results: The results unveil below-average HRQoL scores, emphasizing a notable impact on mental well-being. Notably, "Role Emotional" consistently reflects lower quality of life across various age groups. Gender disparities are observed, with females facing challenges in "Role Physical," while males encounter difficulties in "Role Emotional," "Vitality," and "Mental Health." Age-related differences in "General Health" and "Vitality" highlight the necessity for targeted interventions based on age groups. Logistic regression analysis identifies gender, age, social status, and treatment frequency as significant predictors influencing different components of HRQoL.
Conclusion: The findings underscore the importance of a holistic approach to cancer care, addressing medical, social, and psychological aspects for improved HRQoL and treatment outcomes.
Aliya K. Atabayeva1, http://orcid.org/0000-0001-7725-2255
Zaituna A. Khismetova1, https://orcid.org/0000-0001-5937-3045
Adil Ye. Massalimov2, https://orcid.org/0009-0002-1933-3991
Zhadra Y. Kalbagayeva 1, http://orcid.org/0000-0003-4398-3927
Dinara S. Serikova-Esengeldina1, https://orcid.org/0000-0002-9470-9488
Evgeny L. Borshchuk3, https://orcid.org/0000-0002-0973-6343
1 NCJSC «Semey Medical University», Semey, Republic of Kazakhstan;
2 University Hospital NCJSC «Semey Medical University», Semey, Republic of Kazakhstan;
3Federal State Budgetary Educational Institution of Higher Education "Orenburg State Medical University" of the Ministry of Health of Russia, Orenburg, Russian Federation.
1. Andersen L. et al. Coping Skills Interventions for Fatigue in Adults with Hematologic Malignancies: A Systematic Review // American Journal of Hospice and Palliative Medicine. 2023. Vol. 40, № 2. P. 183–201.
2. Atabayeva A. et al. Health-Related Quality of Life and Treatment Satisfaction of Patients with Blood Cancer in Kazakhstan: A Cross-Sectional Study // Asian Pacific Journal of Cancer Prevention. 2023. Vol. 24, № 7. P. 2397–2403.
3. Bray F. et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries // CA: A Cancer Journal for Clinicians. 2018. Vol. 68, № 6. P. 394–424.
4. Chen C.L. et al. Outcomes and Prognostic Factors in Critical Patients with Hematologic Malignancies // Jour-nal of Clinical Medicine. 2023. Vol. 12, № 3. P. 89.
5. Efficace F. et al. Optimizing health-related quality of life in patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors // Expert Review of Hematology. 2021. Vol. 14, № 3. P. 293–302.
6. Kobayashi D., Morishita S. Physical Exercise and Immune Function in Patients with Hematological Malignan-cies // Physical Therapy and Research in Patients with Cancer. 2023. P. 191–214.
7. Kinoshita Y. et al. Reliability, validity, and responsiveness of the Japanese version of the EORTC QLQ-ELD14 in evaluating the health-related quality of life of elderly patients with cancer // Journal of Cancer Research and Clinical Oncology. 2023. Vol. 149, № 8. P. 4899–4914.
8. Lau C. et al. Disparities in access to palliative care facilities for patients with and without cancer: A retrospec-tive review // Palliative Medicine. 2021. Vol. 35, № 6. P. 1191–1201.
9. Momenimovahed Z. et al. Ovarian cancer in the world: Epidemiology and risk factors // International Journal of Women’s Health. 2019. Vol. 11. P. 287–299.
10. Nct. Calm for Hematological Cancer Sleep Disturbance. https://clinicaltrials.gov/show/NCT05294991. 2022.
11. Sankaranarayanan R., Ramadas K., Qiao Y. lin. Managing the changing burden of cancer in Asia // BMC Medicine. 2014. Vol. 12, № 1. P. 3.
12. Siegel R.L. et al. Cancer statistics, 2023 // CA: A Cancer Journal for Clinicians. 2023. Vol. 73, № 1. P. 17–48.
13. Tsang M. et al. The Value of an Embedded Outpatient Palliative Care Program in Malignant Hematology: Concurrent Care and the Impact on Health Care Utilization // Blood. 2020. Vol. 136, № Supplement 1. P. 14–15.
14. Turdaliyeva B. et al. Prevalence and Associated Factors of Depression Symptoms in Women Newly Diag-nosed with Breast Cancer in Kazakhstan // Asian Pacific Journal of Cancer Prevention. 2022. Vol. 23, № 7. P. 2483–2489.
15. Yfantis A. et al. Health-related quality of life of young women with breast cancer. Review of the literature // Journal of B.U.ON. 2018. Vol. 23, № 1. P. 1–6.
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Atabayeva A.K., Khismetova Z.A., Massalimov A.Ye., Kalbagayeva Zh.Y., Serikova-Esengeldina D.S., Borshchuk E.L. Assessment of the impact of medical and social factors on the quality of life of patients with malignant neoplasms of the blood system // Nauka i Zdravookhranenie [Science & Healthcare]. 2024, (Vol.26) 1, pp. 46-52. doi 10.34689/SH.2024.26.1.006Похожие публикации:
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