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RHEUMATOID ARTHRITIS AND FERTILITY: LITERATURE REVIEW
Introduction. Rheumatoid arthritis is a chronic inflammatory autoimmune disease that leads to disability, which occurs in women of predominantly childbearing age three times more often than men. Unfortunately, the issue of childbirth can be associated not only with the activity of the disease, but also with the availability of comprehensive medical care and knowledge of pharmacological treatment methods. Therefore, many women are struggling to find adequate information about planning pregnancy, childbirth and lactation.
Availability and advanced choice of pharmacotherapy can maintain the... More
Availability and advanced choice of pharmacotherapy can maintain the... More
2019 year | Issue: 2 | Pages: 38-43
FORMATION OF FOCI OF P53 BOUND PROTEIN 1 IN THYROID TUMORS: ACTIVATION OF GENETIC INSTABILITY DURING THYROID CARCINOGENESIS. LITERATURE REVIEW
Introduction: In our days big successes have been reached in studying of molecular–cellular mechanisms in carcinogenesis, establishing the role of oncogens and antioncogens in the development of tumors with various localization, including thyroid cancer. The vast majority of benign and malignant tumors of the thyroid gland develops from the follicular epithelium, which have different degrees of differentiation, different morphogenetic and biochemical features, clinical course and prognosis.
Objective: to conduct a search for scientific information on the activation of genetic instability... More
Objective: to conduct a search for scientific information on the activation of genetic instability... More
2019 year | Issue: 2 | Pages: 25-37
ORGANIZATIONAL BASICS OF SCREENING FOR COLORECTAL CANCER IN WORLD MEDICAL PRACTICE. LITERATURE REVIEW
Actuality Colorectal cancer (CRC) tacked the third place in worldwide common cancer. The revealing of CRC on premalignant, latent and curable stages is important method of decrease of mortality. CRC screening can use direct or indirect tests, delivered opportunistically or via organized programs. Most CRCs are diagnosed after 60 years of age; most screening programs apply to individuals 50-75 years of age.
The purpose of the review is to analyze the approaches and results of screening of colorectal cancer in the world medical practice in order to formulate recommendations for dom... More
The purpose of the review is to analyze the approaches and results of screening of colorectal cancer in the world medical practice in order to formulate recommendations for dom... More
2019 year | Issue: 2 | Pages: 13-24
СОВРЕМЕННЫЕ ТЕНДЕНЦИИ В ЛЕЧЕНИИ БОЛЬНЫХ С ТЯЖЕЛОЙ ЧЕРЕПНО-МОЗГОВОЙ ТРАВМОЙ. ОБЗОР ЛИТЕРАТУРЫ
Актуальность: Проведение интенсивной терапии при тяжелой черепно-мозговой травме – это комплекс мероприятий, направленных на спасение головного мозга и поддержание его функций. Для достижения поставленной задачи необходимо проведение своевременной диагностики и мониторинга критически важных параметров – внутричерепного давления и церебрального перфузионного давления; патогенетически обоснованная терапия и нутритивная поддержка критически больного.
Цель: Целью данного обзора являлся поиск доказательств допустимости применения таких методов, как контроль церебрального перфузионного и внутр... More
Цель: Целью данного обзора являлся поиск доказательств допустимости применения таких методов, как контроль церебрального перфузионного и внутр... More
2019 year | Issue: 2 | Pages: 5-12
OMEGA-3 PUFA AS SECONDARY PROPHYLAXIS OF SUDDEN CARDIAC DEATH AFTER ACUTE MYOCARDIAL INFARCTION: SYSTEMATIC REVIEW AND META-ANALYSIS
Introduction. The incidence of myocardial infarction continues to grow, especially among young and middle-aged people - the incidence rate before the age of 40 reaches 35%. Survivors still have a high risk of recurrent vascular catastrophe: 18% of men and 35% of women suffer a second myocardial infarction over the next 6 years. The experience of countries, including the United States, which have achieved a significant reduction in mortality from CVD, indicates the need to actively address issues of CVD prevention based on the concept of cardiac risk factors.
The implementati... More
The implementati... More
2019 year | Issue: 1 | Pages: 7-20