Online ISSN: 3007-0244,
Print ISSN:  2410-4280
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DIAGNOSTIC SIGNIFICANCE OF THE HE-4 TUMOR MARKER IN THE STAGING OF OVARIAN CANCER

Ovarian cancer is not a rare pathology and accounts for 4–6 % of all malignant neoplasms in the female population. Diagnostics of ovarian cancer at an early stage is a key approach to improving the effectiveness of treatment for this pathology. The use of sensitive serological tumor-associated markers is considered an adequate approach for diagnosis, monitoring of treatment efficacy and preclinical detection of recurrence for tumors of a number of localizations, in particular ovarian cancer.

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2017 year | Issue: 6 | Pages: 28-42

COX REGRESSION IN HEALTH SCIENCES USING SPSS SOFTWARE
In this paper presents theoretical bases of the Cox regression as one of the most popular multidimensional methods of survival analysis. This method of analysis in most cases is used to determine the independent influence of potential risk factors on the rate of occurrence of the event under study during the time period studied. The practical example describes the principles of Cox proportional hazard analysis and the basic principles of interpreting the information received with the SPSS application statistical software package.
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2017 year | Issue: 6 | Pages: 5-27

RISK OF DISORDERS OF NONSPECIFIC RESISTANCE DUE TO LONG-TERM EXPOSURE TO RADIATION IN SMALL DOSES
Background: long-term exposure to ionizing radiation in small doses on the human body is manifested by violations of the adaptive response of regulatory systems to stress.

Aim: to perform a systematic search of valid scientific data in order to assess the disorders of nonspecific resistance in the human organism due to long-term exposure to radiation in small doses

Materials and methods. The search for scientific publications was carried out in the evidence-based medicine’s databases (PubMed, Cochrane Library, ResearchGate, Google Scholar) and in the electron...
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2017 year | Issue: 5 | Pages: 158-171

ASSESSMENT OF PSYCHOLOGICAL STATUS OF THE PEOPLE LIVING IN THE CONDITIONS OF RADIATION EXPOSURE: A SYSTEMATIC REVIEW
Background: the population residing on the territories exposed to ionizing radiation, suffer from many stressors, which creates medical and psychological tension.

Aim: to conduct a systematic search of valid scientific data in order to assess the state of psychological health of population living in ecologically unfavorable territories.

Materials and methods. The search for scientific publications was carried out in the evidence-based medicine’s databases (PubMed, Cochrane Library, TripDatabase, ResearchGate) and in the electronic scientific libraries (Cy...
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2017 year | Issue: 5 | Pages: 145-157

CONGENITAL HEART DISEASES IN CHILDREN COMPLICATED BY PULMONARY HYPERTENSION. DIAGNOSIS AND TREATMENT. LITERATURE REVIEW
Introduction. Congenital heart diseases (CHD) occupy one of the leading places in the structure of the incidence of children and adolescents. The study of congenital heart anomalies, methods of diagnosis and treatment began in the 30s of the XX century. And to date, this problem is relevant for further study, since there are still no algorythm of early diagnostic of the CHD. The most frequent and severe complication of many CHD is pulmonary hypertension, which, when untimely surgical treatment leads to disability and early infant mortality.

Purpose: To study and analyze t...
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2017 year | Issue: 5 | Pages: 129-144