COMBINATIONS OF CONGENITAL HEART DISEASES AND A CONNECTIVE TISSUE DYSPLASIA AMONG CHILDREN OF SEMEY
Introduction. There is evidence on common mechanisms of congenital heart diseases (CHD) and connective tissue dysplasia (CTD), which increases odds for their comorbidities. The latter may be associated with poorer prognosis for CHD. However, the associations between CHD and CTD in Kazakhstan have been poorly studied so far.
Aim – to assess the frequency of CTD signs in children with CHD living in Semey, Kazakhstan.
Materials and methods. We examined 168 children aged 1 to14 years, including 84 – with CHD and 80 children with no signs of CHD.
Associations between CHD and CTD have been studied by Fisher’s exact tests and Pearson’s chi-squared tests where appropriate.
Results: Children with CHD and with CTD had comparable frequency of phenotypical signs of the last. Significant excess of the frequenciest indexes over control group on the majority of signs was observed. Instrumental researches of heart showed very high frequency of signs of CTD at children about CHD. It is revealed that undifferentiated CTD is almost inevitable accompanying syndrome at children with CHD, being observed in 88,1% of cases.
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Мадиева М.Р., Абылгазинова А.Ж., Рымбаева Т.Х. Сочетание врожденных пороков сердца и дисплазии соединительной ткани у детей города Семей / / Наука и Здравоохранение. 2016. № 5. С. 101-110. Madiyevа M.R., Abylgazinova A.Zh., Rymbayevа T.H. Combinations of congenital heart diseases and a connective tissue dysplasia among children of Semey. Nauka i Zdravookhranenie [Science & Healthcare]. 2016, 5, p. 101-110. Мадиева М.Р., Абылгазинова А.Ж., Рымбаева Т.Х., Семей қаласының балаларындағы туа біткен жүрек кемістіктері мен дәнекертін дисплазиясының үйлесуі / / Ғылым және Денсаулық сақтау. 2016. № 5. Б. 101-110.Related publications:
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