Online ISSN: 3007-0244,
Print ISSN:  2410-4280
THE QUALITY OF LIFE OF PATIENTS WITH COPD. LITERATURE REVIEW
Background: Chronic obstructive pulmonary disease (COPD) is a progressive respiratory condition that substantially impairs patients’ health-related quality of life (HRQoL). Beyond lung function deficits, a variety of clinical, psychological, and social factors influence how COPD patients experience their daily lives. Over the past decade, research has increasingly focused on identifying key determinants of QoL in COPD, recognizing that improving QoL is a primary goal of COPD management. This narrative review summarizes evidence (2015–2025) on major factors affecting QoL in COPD patients, including disease severity, comorbid conditions, psychological status, physical activity, exacerbation frequency, social support, access to care, and treatment adherence. Consistent themes and gaps in the literature are highlighted, and we conclude by discussing how these factors interact to shape patient outcomes and where future research is needed. Objective. The primary objective of this review was to summarize and analyze modern approaches aimed at improving the quality of life in patients with chronic obstructive pulmonary disease (COPD). Specific focus was placed on pharmacological therapies, pulmonary rehabilitation, psychosocial interventions, telehealth, self-management education, lifestyle modifications, and integrated care models. Search strategy. A narrative literature review was conducted using electronic databases including PubMed, Scopus, and Cochrane Library. The search included studies published from 2015 to 2025 using keywords such as: “COPD”, “quality of life”, “pulmonary rehabilitation”, “self-management”, “psychological interventions”, “digital health”, “triple therapy”, and “integrated care”. Preference was given to systematic reviews, randomized controlled trials, and high-quality cohort studies published in peer-reviewed journals in English. Results and conclusions. Recent studies confirm that various modern interventions can significantly improve the quality of life in COPD patients. Optimized pharmacological treatments, particularly triple inhaler therapy, help reduce symptoms and exacerbations. Pulmonary rehabilitation consistently enhances physical function and well-being. Psychological support, including cognitive-behavioral therapy, reduces anxiety and depression, positively affecting emotional health. Telehealth and mobile tools improve patient engagement and self-management, while structured education programs lead to better disease control and reduced hospital visits. Nutritional support and regular physical activity improve strength, endurance, and daily functioning. Integrated, multidisciplinary care models have shown the strongest overall impact, improving both quality of life and healthcare outcomes when delivered in a coordinated and patient-centered manner.
Калбагаева Жадра Ерболовна - докторант 1-го года обучения по специальности «Общественное здравоохранение», НАО "Медицинский университет Семей". г. Семей, Республика Казахстан. Почтовый индекс: Республика Казахстан, 071400, г. Семей, ул. Абая, д.103. E-mail: zhadra.kalbagayeva@edu.med.kz Телефон: +77771315558
1. Akor A.A., Bamidele A., Erhabor G.E. Predictors of Health-Related Quality of Life (HRQOL) in Patients With Chronic Obstructive Pulmonary Disease using the COPD Assessment Test (CAT) // West African Journal of Medicine. 2020. № 3 (37). p. 275–280. 2. Aravantinou-Karlatou A. et al. The Influence of Social Support in PROMs of Patients with COPD in Primary Care: A Scoping Review // Healthcare. 2023. № 24 (11). p. 3141. 3. Breen A. et al. What is the impact of home non-invasive ventilation on the health-related quality of life of patients with chronic obstructive pulmonary disease? A systematic review // Quality of Life Research: An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation. 2023. № 7 (32). p. 1843–1857. 4. Ceyhan Y., Tekinsoy Kartin P. The effects of breathing exercises and inhaler training in patients with COPD on the severity of dyspnea and life quality: a randomized controlled trial // Trials. 2022. № 1 (23). p. 707. 5. Chang H. et al. Comparative effectiveness of eHealth interventions on the exercise endurance and quality of life of patients with COPD: A systematic review and network meta-analysis // Journal of Clinical Nursing. 2024. № 9 (33). p. 3711–3720. 6. Collins P. F., Elia M., Stratton R. J. Nutritional support and functional capacity in chronic obstructive pulmonary disease: a systematic review and meta-analysis // Respirology (Carlton, Vic.). 2013. № 4 (18). p. 616–629. 7. Criner G.J. et al. COPD Advanced Patient Management // Chest. 2018. № 6 (153). p. 1497–1498. 8. Dong J. et al. Efficacy of pulmonary rehabilitation in improving the quality of life for patients with chronic obstructive pulmonary disease: Evidence based on nineteen randomized controlled trials // International Journal of Surgery (London, England). 2020. (73). p. 78–86. 9. Esteban C. et al. Predictive factors over time of health-related quality of life in COPD patients // Respiratory Research. 2020. № 1 (21). p. 138. 10. Farver-Vestergaard I., Jacobsen D., Zachariae R. Efficacy of psychosocial interventions on psychological and physical health outcomes in chronic obstructive pulmonary disease: a systematic review and meta-analysis // Psychotherapy and Psychosomatics. 2015. № 1 (84). p. 37–50. 11. Fazekas-Pongor V. et al. Health-related quality of life of COPD patients aged over 40 years // Physiology International. 2021,p.1-10. 12. Fei F. et al. Synergistic Impact of the Symptom Cluster on Health-Related Quality of Life in Patients With Chronic Obstructive Pulmonary Disease: A Secondary Data Analysis // Clinical Nursing Research. 2022. № 6 (31). p. 991–999. 13. Ferrone M. et al. The impact of integrated disease management in high-risk COPD patients in primary care // NPJ primary care respiratory medicine. 2019. № 1 (29). p. 8. 14. Halpin D.M.G. et al. Global Initiative for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease. The 2020 GOLD Science Committee Report on COVID-19 and Chronic Obstructive Pulmonary Disease // American Journal of Respiratory and Critical Care Medicine. 2021. № 1 (203). p. 24–36. 15. Horner A. et al. Physical Activity, Depression and Quality of Life in COPD - Results from the CLARA II Study // International Journal of Chronic Obstructive Pulmonary Disease. 2023. (18). p. 2755–2767. 16. Hurst J.R. et al. Understanding the impact of chronic obstructive pulmonary disease exacerbations on patient health and quality of life // European Journal of Internal Medicine. 2020. (73). p. 1–6. 17. Jang S.M. et al. Depression is a major determinant of both disease-specific and generic health-related quality of life in people with severe COPD // Chronic Respiratory Disease. 2019. (16). p. 1479972318775422. 18. Janjua S. et al. Digital interventions for the management of chronic obstructive pulmonary disease // The Cochrane Database of Systematic Reviews. 2021. № 4 (4). p. CD013246. 19. Jarab A. et al. Patients’ perspective of the impact of COPD on quality of life: a focus group study for patients with COPD // International Journal of Clinical Pharmacy. 2018. № 3 (40). p. 573–579. 20. Jones G.L. Quality of life changes over time in patients with chronic obstructive pulmonary disease // Current Opinion in Pulmonary Medicine. 2016. № 2 (22). C. 125–129. 21. Kharbanda S., Anand R. Health-related quality of life in patients with chronic obstructive pulmonary disease: A hospital-based study // The Indian Journal of Medical Research. 2021. № 4 (153). p. 459–464. 22. Koarai A. et al. Triple versus LAMA/LABA combination therapy for patients with COPD: a systematic review and meta-analysis // Respiratory Research. 2021. № 1 (22). p. 183. 23. Levy A.R. et al. An intervention for pulmonary rehabilitators to develop a social identity for patients attending exercise rehabilitation: a feasibility and pilot randomised control trial protocol // Pilot and Feasibility Studies. 2018. (4). p. 40. 24. Li Y. et al. Breathing Exercises in the Treatment of COPD: An Overview of Systematic Reviews // International Journal of Chronic Obstructive Pulmonary Disease. 2022. (17). p. 3075–3085. 25. Liang Z. et al. What conservative interventions can improve the long-term quality of life, depression, and anxiety of individuals with stable COPD? A systematic review and meta-analysis // Quality of Life Research: An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation. 2022. № 4 (31). p. 977–989. 26. Lipson D.A. et al. Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD // The New England Journal of Medicine. 2018. № 18 (378). p. 1671–1680. 27. Liu H. et al. Group singing improves depression and life quality in patients with stable COPD: a randomized community-based trial in China // Quality of Life Research: An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation. 2019. № 3 (28). p. 725–735. 28. Matsunaga K. et al. Comorbid Conditions in Chronic Obstructive Pulmonary Disease: Potential Therapeutic Targets for Unmet Needs // Journal of Clinical Medicine. 2020. № 10 (9). p. 3078. 29. McCarthy B. et al. Pulmonary rehabilitation for chronic obstructive pulmonary disease // The Cochrane Database of Systematic Reviews. 2015. № 2 (2015). p. CD003793. 30. Meijer E. et al. Exploring characteristics of COPD patients with clinical improvement after integrated disease management or usual care: post-hoc analysis of the RECODE study // BMC pulmonary medicine. 2020. № 1 (20). p. 176. 31. Mohsen S. et al. Nonadherence to treatment and quality of life among patients with chronic obstructive pulmonary disease // Lung India: Official Organ of Indian Chest Society. 2019. № 3 (36). p. 193–198. 32. Nagase F.I. et al. Effectiveness of remote home monitoring for patients with Chronic Obstructive Pulmonary Disease (COPD): systematic review // BMC health services research. 2022. № 1 (22). p. 646. 33. Poot C. C. et al. Integrated disease management interventions for patients with chronic obstructive pulmonary disease // The Cochrane Database of Systematic Reviews. 2021. № 9 (9). p. CD009437. 34. Qian Y. et al. Analyses of Factors Associated with Acute Exacerbations of Chronic Obstructive Pulmonary Disease: A Review // International Journal of Chronic Obstructive Pulmonary Disease. 2023. (18). p. 2707–2723. 35. Qiu C.-J., Wu S. Depression and anxiety disorders in chronic obstructive pulmonary disease patients: Prevalence, disease impact, treatment // World Journal of Psychiatry. 2024. № 12 (14). p. 1797–1803. 36. Rahi M.S. et al. The Impact of Anxiety and Depression in Chronic Obstructive Pulmonary Disease // Advances in Respiratory Medicine. 2023. № 2 (91). p. 123–134. 37. Rosińczuk J., Przyszlak M., Uchmanowicz I. Sociodemographic and clinical factors affecting the quality of life of patients with chronic obstructive pulmonary disease // International Journal of Chronic Obstructive Pulmonary Disease. 2018. (13). p. 2869–2882. 38. Rosińczuk J., Przyszlak M., Uchmanowicz I. Sociodemographic and clinical factors affecting the quality of life of patients with chronic obstructive pulmonary disease // International Journal of Chronic Obstructive Pulmonary Disease. 2018. (13). p. 2869–2882. 39. Rzadkiewicz M., Nasiłowski J. Psychosocial Interventions for Patients with Severe COPD-An Up-to-Date Literature Review // Medicina (Kaunas, Lithuania). 2019. № 9 (55). p. 597. 40. Saja M.F. et al. The Association Between Medication Adherence and Health-Related Quality of Life in Patients with COPD: A Cross-Sectional Study // International Journal of Chronic Obstructive Pulmonary Disease. 2025. (20). p. 1567–1583. 41. Schrijver J. et al. Self-management interventions for people with chronic obstructive pulmonary disease // The Cochrane Database of Systematic Reviews. 2022. № 1 (1). p. CD002990. 42. Shatto J.A., Stickland M.K., Soril L.J.J. Variations in COPD Health Care Access and Outcomes: A Rapid Review // Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 2024. № 2 (11). p. 229–246. 43. Shioya T. et al. Improvement of physical activity in chronic obstructive pulmonary disease by pulmonary rehabilitation and pharmacological treatment // Respiratory Investigation. 2018. № 4 (56). p. 292–306. 44. Wang J. et al. The complexity of mental health care for people with COPD: a qualitative study of clinicians’ perspectives // NPJ primary care respiratory medicine. 2021. № 1 (31). p. 40. 45. Wang J.G. et al. Clinical Characteristics of Patients With COPD and Comorbid Depression and Anxiety: Data From a National Multicenter Cohort Study // Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 2025. № 1 (12). p. 33–42. 46. Wedzicha J.A. et al. Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline // The European Respiratory Journal. 2017. № 3 (49). p. 1600791. 47. Weina J. et al. Therapeutic effects of statins drugs use and continuous nursing on patients with chronic obstructive pulmonary disease and the influence of life quality // Pakistan Journal of Pharmaceutical Sciences. 2018. № 3(Special) (31). p. 11794–11184. 48. Yi M. et al. Impact of Caregiving Burden on Quality of Life of Caregivers of COPD Patients: The Chain Mediating Role of Social Support and Negative Coping Styles // International Journal of Chronic Obstructive Pulmonary Disease. 2021. (16). p. 2245–2255. 49. Yu C.-H. et al. Dynamic changes in quality of life in older patients with chronic obstructive pulmonary disease: a 7-year follow up // Health and Quality of Life Outcomes. 2024. № 1 (22). p. 76. 50. Yun R. et al. How Breathing Exercises Influence on Respiratory Muscles and Quality of Life among Patients with COPD? A Systematic Review and Meta-Analysis // Canadian Respiratory Journal. 2021. (2021). p. 1904231. 51. Zakrisson A.-B. et al. Improved quality of care by using the PRISMS form to support self-management in patients with COPD: A Randomised Controlled Trial // Journal of Clinical Nursing. 2020. № 13–14 (29). p. 2410–2419. 52. Zhang J.-H. Effect of Nutritional Management on the Nutritional Status and Quality of Life of Patients with Chronic Obstructive Pulmonary Disease // International Journal of Chronic Obstructive Pulmonary Disease. 2025. (20). p. 487–496. 53. Zhang S. et al. Evaluation of the quality of life in patients with LC-COPD and the impact of inhalation therapy on the quality of life // Panminerva Medica. 2022. № 3 (64). p. 411–412. 54. Zhang Z.-Y., Li Y.-H. Effects of different exercise regimens on prognosis of patients with chronic obstructive pulmonary disease: a systematic reviews and meta-analysis // Annals of Medicine. 2024. № 1 (56). p. 2392022.
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Kalbagayeva Zh.Ye., Khismetova Z.A., Iskakova N.S., Atabayeva A.K., Serikova-Esengeldina D.S. Razakova N.G., Zheksebergenova A.В. The quality of life of patients with COPD. Literature review // Nauka i Zdravookhranenie [Science & Healthcare]. 2025. Vol.27 (3), pp. 215-226. doi 10.34689/SH.2025.27.3.023

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