ФАКТОРЫ, ВЛИЯЮЩИЕ НА ОДНОЛЕТНЮЮ ВЫЖИВАЕМОСТЬ ПАЦИЕНТОВ ПОСЛЕ ИНСУЛЬТА В КАЗАХСТАНЕ: КОГОРТНОЕ ИССЛЕДОВАНИЕ
Введение. Существует много нерешенных вопросов относительно предикторов исхода мозгового инсульта (МИ). В литературе имеется единичные публикации по детерминантам исхода МИ в Казахстане, несмотря на высокую распространенность проблемы.
Целью настоящего исследования являлось оценка влияния факторов риска на выживаемость больных с инсультом в течение года в популяции г. Семей.
Методы. В когортное исследование были включены все случаи МИ в г. Семей с 01.01.2014г. до 31.12.15г. (n=937). Выживаемость больных с МИ оценивалась с помощью метода Kaплана-Mайера с определение... Толығырақ
Целью настоящего исследования являлось оценка влияния факторов риска на выживаемость больных с инсультом в течение года в популяции г. Семей.
Методы. В когортное исследование были включены все случаи МИ в г. Семей с 01.01.2014г. до 31.12.15г. (n=937). Выживаемость больных с МИ оценивалась с помощью метода Kaплана-Mайера с определение... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 46-57
ПОЛИМОРФИЗМ ГЕНА ИЛ10 В ПОЛОЖЕНИИ -1082G/A У БОЛЬНЫХ РОЖЕЙ
Целью данного исследования является выявление связи полиморфизма гена ИЛ10-1082 GA (rs1800896) с заболеванием рожей у лиц казахской национальности.
Материалы и методы: Полиморфизм гена ИЛ10-1082 GA изучен у 206 больных рожей и 422 лиц контрольной группы. Из них у 143 больных первичной рожей и 63 больных рецидиврующей рожей. Для генотипирования были выделены геномная ДНК из крови. Генотипирование проводили методом полимеразной цепной реакции в режиме реал-тайм. Для статистической обработки использовались критерий χ2Пирсона и отношение шансов (ОШ) с 95% доверительными ... Толығырақ
Материалы и методы: Полиморфизм гена ИЛ10-1082 GA изучен у 206 больных рожей и 422 лиц контрольной группы. Из них у 143 больных первичной рожей и 63 больных рецидиврующей рожей. Для генотипирования были выделены геномная ДНК из крови. Генотипирование проводили методом полимеразной цепной реакции в режиме реал-тайм. Для статистической обработки использовались критерий χ2Пирсона и отношение шансов (ОШ) с 95% доверительными ... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 34-45
ИЗМЕНЕНИЯ В ПЛАЗМЕ ТРИЙОДТИРОНИНА, ТИРОКСИНА И ТИРЕОТРОПНОГО ГОРМОНА ПОСЛЕ ОБЛУЧЕНИЯ 131 I У НОВОРОЖДЕННЫХ КРЫС, СОДЕРЖАВШИХСЯ НА ЙОДОДЕФИЦИТНОМ ПИТАНИИ
Background: Human thyroid gland is generally regarded as a relatively low-risk organ in terms of developing radiation-induced tumorigenesis. However, a rapid increase in the incidents of thyroid cancer after the Chernobyl nuclear reactor accident in 1986 provided additional insight into the risk of thyroid cancer. Three key risk factors have been identified to be involved in this increase: (1) internal irradiation from 131I fallout, (2) young age, and (3) a low-iodine diet. Our previous study demonstrated that the thyroid radiation dose was highest in the newborn rats f...
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 26-33
СРАВНЕНИЕ КОЛИЧЕСТВЕННЫХ ДАННЫХ ДВУХ ПАРНЫХ ВЫБОРОК С ИСПОЛЬЗОВАНИЕМ ПРОГРАММНОГО ОБЕСПЕЧЕНИЯ STATISTICA И SPSS: ПАРАМЕТРИЧЕСКИЕ И НЕПАРАМЕТРИЧЕСКИЕ КРИТЕРИИ
В настоящей работе представлены общие сведения об использовании парного критерия Стьюдента, непараметрического критерия Вилкоксона и критерия знаков для сравнения количественных признаков парных выборок. Описан алгоритм расчета данных критериев с использованием программного обеспечения Statistica 10 и SPSS 20 и представлена интерпретация результатов расчетов. Настоящая статья призвана дать общие сведения об использовании парного критерия Стьюдента, парного критерия Вилкоксона и критерия знаков, и не заменяет прочтения специализированной литературы по статистике и клинической эпидемиологии.
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 5-25
СРАВНИТЕЛЬНЫЙ АНАЛИЗ РАСПРЕДЕЛЕНИЯ РАБОЧЕГО ВРЕМЕНИ У СОТРУДНИКОВ ОТДЕЛЕНИЙ ХИРУРГИЧЕСКОГО ПРОФИЛЯ ПРИ ИСПОЛЬЗОВАНИИ МЕДИЦИНСКОЙ ИНФОРМАЦИОННОЙ СИСТЕМЫ
2016 жыл | Шығарылым: 2 | Беттер: 150-161
COMPARATIVE EVALUATION OF BLOOD COLLECTION TUBES AND EXTRACTION METHODS FOR CIRCULATING TUMOR DNA
2025 жыл | Шығарылым: 6 | Беттер: 7-13
INFLUENCE OF SEX HORMONE-BINDING GLOBULIN (SHBG) ON THE LEVEL OF FREE TESTOSTERONE FRACTION IN OLDER OVERWEIGHT MEN
2025 жыл | Шығарылым: 6 | Беттер: 14-20
ASSESSMENT OF THE PROBABILITY OF DEVELOPING CARDIORENAL SYNDROME TYPE 2 DEPENDING ON POTENTIAL BIOMARKERS IN PEDIATRIC PATIENTS
2025 жыл | Шығарылым: 6 | Беттер: 21-29
MORPHO-GENETIC VARIABILITY IN MYOCARDIAL TISSUE AFTER SEPTAL MYECTOMY IN PATIENTS WITH OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY: A FOUR-CASE SERIES STUDY
2025 жыл | Шығарылым: 6 | Беттер: 30-37
CLINICAL EFFICACY OF SELECTIVE PLASMA FILTRATION (EVACLIO) IN CARDIOVASCULAR COMPLICATIONS: A CASE SERIES FROM THE HEART CENTER KAZAKHSTAN
2025 жыл | Шығарылым: 6 | Беттер: 38-46
INFLUENCE OF THE ECOSYSTEM ON HUMAN HEALTH IN THE INDUSTRIAL DEVELOPED REGIONS OF KAZAKHSTAN. A LITERATURE REVIEW
Introduction: In most regions of our republic, the environmental situation is not only unfavorable, but also catastrophic. Ecological problems of large cities of Kazakhstan are associated with the development of mining, non-ferrous and ferrous metallurgy. Excessively high concentration of the population, transport and industrial enterprises leads to a violation of the ecological balance of the natural environment. Air pollution is also one of the main causes of ecosystem damage, which adversely affects human health.
Purpose: to conduct a systematic search for scientific information on th... Толығырақ
Purpose: to conduct a systematic search for scientific information on th... Толығырақ
2018 жыл | Шығарылым: 4 | Беттер: 107-132
THE MODERN POSSIBILITIES OF PREDICTION OF PRE-ECLAMPSIA AND ITS COMPLICATIONS. A LITERATURE REVIEW
Background: One of the main causes of maternal and perinatal morbidity and mortality around the world is hypertensive disorder during pregnancy. After diagnosis of severe preeclampsia it is necessary of accurate risk assessment and management for both the mother and the fetus at different times. The prognostic model is an alternative basis for clinical practice, for predicting patient's future outcomes and for making decisions to improve them.
The aim: analysis of literature data of models for the prediction of pre-eclampsia and its complications.
Materials and metho... Толығырақ
The aim: analysis of literature data of models for the prediction of pre-eclampsia and its complications.
Materials and metho... Толығырақ
2018 жыл | Шығарылым: 4 | Беттер: 86-106
IMPROVEMENT OF METHODS OF TREATMENT OF GIPOSPADIA IN CHILDREN. STUDY PROTOCOL.
Introduction. Hypospodias refers to widespread anomalies of the genital organs. Treatment of hypospadias in children is performed only surgically. The variety of applied methods of treatment is caused by a large number of complications and the search for the optimal method of surgery for the correction of hypospadias.
The aim: to improve the results of treatment of anterior and middle hypospadias in children by introducing a modified urethroplasty method with a flap of the foreskin on the “feeding leg” and reducing postoperative complications.
Objectives:
1. ... Толығырақ
The aim: to improve the results of treatment of anterior and middle hypospadias in children by introducing a modified urethroplasty method with a flap of the foreskin on the “feeding leg” and reducing postoperative complications.
Objectives:
1. ... Толығырақ
2018 жыл | Шығарылым: 4 | Беттер: 73-85
CLINICAL RESULTS OF TREATMENT OF ANKLES FRACTURES WITH STOP RECOGNITION WITH USE OF THE APPARATUS FOR ACCURATE SPICE
Relevance: Ankle fractures are among the most common injuries of the lower limb. The greatest difficulties in their treatment are multi-ankles fractures with a dislocation of the foot. Transarticular spinal fixation attracts by the ease of holding, by the stability of the joint. However, the complications associated with the incorrect position of the locking spokes are likely. The device for exact carrying out of spokes promotes creation of conditions for stable fixation and reduction of frequency of complications.
The purpose of the study was to improve the technique of carrying the spo... Толығырақ
The purpose of the study was to improve the technique of carrying the spo... Толығырақ
2018 жыл | Шығарылым: 4 | Беттер: 61-72
OVERWEIGHT AND OBESITY AS A PREDISPOSITION FOR OSTEOPENIC CONDITION DEVELOPMENT IN A PATIENT WITH CORONARY ARTERY DISEASE
Relevance. Сalcification of arterial tissue is not just a passive process of calcium phosphate precipitation or adsorption in the terminal stage of arteriosclerosis, but also a highly organized process that is regulated by mechanisms analogous to bone mineralization.
Aim: to optimize the diagnosis of the structural and functional state of bone tissue in patients with coronary artery disease and obesity, and to determine the possible interrelationbetween these specifiedparameters and lipid metabolism indicators.
Materials and methods: A cohort prospective study conducted from 2016 t... Толығырақ
Aim: to optimize the diagnosis of the structural and functional state of bone tissue in patients with coronary artery disease and obesity, and to determine the possible interrelationbetween these specifiedparameters and lipid metabolism indicators.
Materials and methods: A cohort prospective study conducted from 2016 t... Толығырақ
2018 жыл | Шығарылым: 4 | Беттер: 50-60