ОТДАЛЕННЫЕ ЭФФЕКТЫ РАЗЛИЧНЫХ ДОЗОВЫХ НАГРУЗОК ГАММА-ИЗЛУЧЕНИЯ НА НЕСПЕЦИФИЧЕСКУЮ ФАГОЦИТАРНУЮ РЕЗИСТЕНТНОСТЬ ОРГАНИЗМА
В ближайшем и отдаленном периодах все виды дозовых нагрузок вызывают повышение неспецифической фа-гоцитарной резистентности организма, степень напряжения адаптационных механизмов зависит от дозы гамма-излучения.
Толығырақ
2014 жыл | Шығарылым: 3 | Беттер: 40-42
ОТДАЛЕННЫЕ ЭФФЕКТЫ РАЗЛИЧНЫХ ДОЗОВЫХ НАГРУЗОК ГАММА-ИЗЛУЧЕНИЯ НА ГУМОРАЛЬНОЕ ЗВЕНО ИММУНИТЕТА
В отдаленном периоде после различных дозовых нагрузок гамма-излучения отмечается увеличение количества СД19+лимфоцитов, снижение антителообразования в селезенке, концентрации ЦИК в сыворотке крови и по-вышение индекса супрессии.
Толығырақ
2014 жыл | Шығарылым: 3 | Беттер: 43-45
ОТДАЛЕННЫЕ ЭФФЕКТЫ СУБЛЕТАЛЬНОЙ ДОЗЫ ГАММА-ИЗЛУЧЕНИЯ НА ИММУНОЛОГИЧЕСКУЮ РЕАКТИВНОСТЬ ОРГАНИЗМА
В эксперименте выявлено, что в отдаленном периоде после действия сублетальной дозы гамма-излучения отмечается повышение субпопуляций Т-лимфоцитов с хелперной активностью и понижение Т-лимфоцитов с су-прессорной активностью. Восстанавливается функциональная способность в клеточном звене иммунитета, повышаются функциональные способности неспецифического фагоцитарного звена иммунитета, и проявляется недостаточность в гуморальном звене иммунитета.
Толығырақ
2014 жыл | Шығарылым: 3 | Беттер: 46-48
ОТДАЛЕННЫЕ ЭФФЕКТЫ ФРАКЦИОНИРОВАННОГО ГАММА-ИЗЛУЧЕНИЯ НА ИММУННУЮ СИСТЕМУ ОРГАНИЗМА
В отдаленном периоде после фракционированного гамма-облучения повышена активность неспецифической фагоцитарной резистентности организма, отмечается дисфункция в гуморальном звене иммунитета, на фоне увеличения общего количества лимфоцитов отмечается повышение пула СД3+, СД4+лимфоцитов, иммунорегу-ляторного индекса, нормализация лимфокинпродуцирующей способности лимфоцитов и снижение пула СД8+ лимфоцитов.
Толығырақ
2014 жыл | Шығарылым: 3 | Беттер: 49-52
АНАЛИЗ ДЕЯТЕЛЬНОСТИ МЕДИЦИНСКИХ УЧРЕЖДЕНИЙ, ОКАЗЫВАЮЩИЕ ПЕРВИЧНУЮ МЕДИКО-САНИТАРНУЮ ПОМОЩЬ ПО БЕСКАРАГАЙСКОМУ РАЙОНУ ЗА ПЕРИОД С 2011 ПО 2013 ГОД
В статье приведены результаты анализа деятельности медицинских учреждений по Бескарагайскому району за 2011-2013 годы.
Толығырақ
2014 жыл | Шығарылым: 3 | Беттер: 53-54
THE EVOLUTION AND IMPLEMENTATION OF THE ADVANCED PRACTICE NURSE MODEL IN DEVELOPED AND DEVELOPING COUNTRIES. LITERATURE REVIEW
2025 жыл | Шығарылым: 6 | Беттер: 220-230
IMPROVED RECOGNITION OF ADULT-ONSET COMMON VARIABLE IMMUNODEFICIENCY FOLLOWING A TARGETED EDUCATIONAL WORKSHOP: A CASE SERIES FROM KAZAKHSTAN
2025 жыл | Шығарылым: 6 | Беттер: 231-236
NEW TECHNIQUE OF ANTERIOR MITRAL LEAFLET PLICATION FOR CORRECTION OF SAM SYNDROME IN OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY. CLINICAL CASE
2025 жыл | Шығарылым: 6 | Беттер: 237-243
COMBINATION OF ATYPICAL HEMOLYTIC UREMIC SYNDROME AND IGA NEPHROPATHY : A CASE REPORT AND LITERATURE REVIEW
2025 жыл | Шығарылым: 6 | Беттер: 244-250
GENETIC VARIANTS IN LIPID-ASSOCIATED GENES IN THE KAZAKHSTANI COHORT WITH ATHEROSCLEROSIS AND HYPERTRIGLYCERIDEMIA
2025 жыл | Шығарылым: 5 | Беттер: 7-15
WAYS OF IMPROVING THE QUALITY AND ENHANCING THE ECONOMIC EFFICIENCY OF NATIONAL SCREENING PROGRAM FOR THE EARLY DETECTION OF ONCOLOGICAL DISEASES (FOR EXAMPLE PAVLODAR REGION). STUDY PROTOCOL.
Introduction. In Kazakhstan, the national screening program for the early detection of diseases was introduced in 2011. It is noted the low efficiency of the National screening program, the effectiveness of screening is not monitored on the basis of the recommendations on the effectiveness of early detection of cancer and their successful treatment.
Methods / design. The purpose of this study: to develop measures to improve results and increase cost-effectiveness of national screening program for early detection of oncological diseases. Studied nosologies: cervical cancer, breast ... Толығырақ
Methods / design. The purpose of this study: to develop measures to improve results and increase cost-effectiveness of national screening program for early detection of oncological diseases. Studied nosologies: cervical cancer, breast ... Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 97-111
VIDEO ENDOSCOPE TECHNOLOGY WITH MINIMALLY INVASIVE SURGICAL TREATMENT OF PATIENTS WITH CORONARY HEART DISEASE: CASE SERIES REPORT
Coronary artery bypass surgery with using endoscopic technology is the most recent trend of surgical treatment of coronary heart disease.
The purpose of this work is to present the experience of the 8 video assistant cardiac surgery in a "Pavlodar Regional Cardiological Center" for the period from 2012 to 2016.
Materials and methods. Design - case series. All 8 patients underwent minimal-ivasive direct coronary artery bypass off pump, with endoscopic release of the left internal mammary artery (LIMA), and making anastomosis LIMA to left anterior desc... Толығырақ
The purpose of this work is to present the experience of the 8 video assistant cardiac surgery in a "Pavlodar Regional Cardiological Center" for the period from 2012 to 2016.
Materials and methods. Design - case series. All 8 patients underwent minimal-ivasive direct coronary artery bypass off pump, with endoscopic release of the left internal mammary artery (LIMA), and making anastomosis LIMA to left anterior desc... Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 87-96
COMMENTS ON 2016 EUROPEAN GUIDELINES FOR THE MANAGEMENT OF ATRIAL FIBRILLATION: NEW ASPECTS FOR PHYSICIANS
Updated European guidelines for the management of atrial fibrillation were published on the 27 of August, 2016. This document is remarkable for new recommendations, especially about anticoagulation therapy. Key points of these guidelines and the possibility of their use in our country are described in the article.
Objective: to find out essential evidence-based key points of the 2016 guidelines and to investigate the possibility of their use in Kazakhstan.
Materials and methods: To achieve these goals major differences between 2016, 2012, 2010 guidelines were analyze... Толығырақ
Objective: to find out essential evidence-based key points of the 2016 guidelines and to investigate the possibility of their use in Kazakhstan.
Materials and methods: To achieve these goals major differences between 2016, 2012, 2010 guidelines were analyze... Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 74-86
IMMUNOHISTOCHEMICAL ANALYSIS EXPRESSION TP73 IN ONCOCYTIC FOLLICULAR ADENOMA OF THE THYROID
Oncocytic follicular adenomas (FAs) of the thyroid are cells neoplasms of follicular origin that predominantly consist of large polygonal cells with eosinophilic and granular cytoplasm. According to some scientific studies, TP73 might play a сertain role in tumor genesis (oncogenesis). Moreover, due to the absence of p53, oncogenes may attract p73 to induce apoptosis in tumor cells. TP53 is a crucial tumor suppressor in preventing the cancerous transformation of cells. There was also a particular focus on the amplification of 1p36 chromosome in oncocytic FA, which contains a t...
Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 64-73
ASSESSMENT OF TOXICITY OF NEOADJUVANT CHEMOTHERAPY FOR LOCALLY ADVANCED BREAST CANCER
Introduction. In the structure of malignancies in women breast cancer (BC) takes 1st place. In locally advanced breast cancer (LABC) treatment begins with neoadjuvant chemotherapy (CTX), the standard protocols are CMF, FAC, AC. In the trial, we used cytostatic Arglabin isolated from plants endemic to Central Kazakhstan - wormwood smooth, as monotherapy and as addition to AC-protocol.
The objective of the trial - to assess the toxicity of different protocols of neoadjuvant CTX of LABC.
Methods: 93 patients with LABC (T2N1-2M0, T3N0-2M0) ... Толығырақ
The objective of the trial - to assess the toxicity of different protocols of neoadjuvant CTX of LABC.
Methods: 93 patients with LABC (T2N1-2M0, T3N0-2M0) ... Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 52-63