RADIATION-INDUCED KI-67 PROLIFERATION IN THE SMALL INTESTINE OF RATS
Introduction. It is known that Hiroshima and Nagasaki were target of the first atomic bombs in the history of mankind. As a result, the population of Japanese cities was exposed to internal and external irradiation. Numerous authors maintain that primary neutron-activated radionuclides are chemical elements 56Mn and 60Co. Herewith, 56Mn was determined the dominant role of neutrons induced by β-radiation during the first few hours after the atomic bombing. The systemic access in estimation of Кi-67 marker in radiosensitive small intestine defining the functional state and the interrelation of s...
Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 63-73
EVALUATION OF THE EFFECTIVENESS OF FIRST AID TRAINING IN SHOPPING CENTER EMPLOYEES
Introduction: Cardiopulmonary arrest is on of the most important causes requiring first aid in big metropolis. Cardiac arrest may be often seen in airports, shopping centers (SC), prisons, sports facilities, industrial zones, public transport stations and nursing homes. In this study, we aimed to evaluate effectiveness of training by measuring knowledge level of SC employees before and after first aid training, and to create awareness for the presence and use of automatic external defibrillator.
Material & Methods: Employees of a shopping center were trained for first aid on vol... Толығырақ
Material & Methods: Employees of a shopping center were trained for first aid on vol... Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 58-62
ANALYSIS OF THE PATIENTS ADMITTED TO OUR EMERGENCY DEPARTMENT DUE TO CHRONIC OBSTRUCTIVE PULMONARY DISEASE EXACERBATION
Objective: Chronic Obstructive Pulmonary Disease (COPD) is the fourth most common cause of death in the world according to the reports of the World Health Organisation (WHO). Exacerbations impair the quality of life, fastens the progression of the disease and, thus, plays an important role in the morbidity and mortality of the disease. In this study with, we aimed to investigate the factors effecting the characteristics of the patients admitted to our emergency department (ED) due to COPD exacerbation in term of management, dischargement, hospitalization and ...
Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 50-57
ПРОГНОСТИЧЕСКОЕ ЗНАЧЕНИЕ ПОЧЕЧНОЙ ДИСФУНКЦИИ У БОЛЬНЫХ ИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА ПОСЛЕ РЕВАСКУЛЯРИЗАЦИИ МИОКАРДА
Цель исследования. Изучение распространенности почечной дисфункции (ПД) и ее прогностической значимости у больных ишемической болезнью сердца (ИБС), перенесших реваскуляризацию миокарда.
Материалы и методы. Проведен одномоментный ретроспективный анализ историй болезни 675 пациентов кардиологического отделения, в анамнезе которых - перенесенное чрескожное коронарное вмешательство (ЧКВ) и/или аортокоронарное шунтирование (АКШ). Изучены распространенность факторов риска, особенности коронарного кровотока, структурно-функциональные изменения сердца.
Ста... Толығырақ
Материалы и методы. Проведен одномоментный ретроспективный анализ историй болезни 675 пациентов кардиологического отделения, в анамнезе которых - перенесенное чрескожное коронарное вмешательство (ЧКВ) и/или аортокоронарное шунтирование (АКШ). Изучены распространенность факторов риска, особенности коронарного кровотока, структурно-функциональные изменения сердца.
Ста... Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 42-49
ПОСЛЕОПЕРАЦИОННЫЕ ВЕНТРАЛЬНЫЕ ГРЫЖИ. ХИРУРГИЧЕСКОЕ ЛЕЧЕНИЕ И ПРОФИЛАКТИКА РАНЕВЫХ ОСЛОЖНЕНИЙ. ОБЗОР ЛИТЕРАТУРЫ
Введение. В современной Казахстанской и зарубежной литературе немалое число работ посвящено изучению послеоперационных вентральных грыж. Однако результаты их хирургического лечения не всегда устраивают как клиницистов, так и самих пациентов [5, 9, 47, 53, 55, 74]. Развитие инфекционных раневых осложнений в послеоперационном периоде - одна из причин увеличения длительности госпитализации, возникновения рецидива грыжи, роста расходов на лечение [34, 76, 78, 79].
Цель. Провести обзор литературных данных по вопросам хирургического лечения послеоперационных вентральных грыж и профилактики ран... Толығырақ
Цель. Провести обзор литературных данных по вопросам хирургического лечения послеоперационных вентральных грыж и профилактики ран... Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 29-41
PRELIMINARY ANALYSIS OF THE HEALTH STATUS AND RADIATION DOSES OF RESIDENTS OF THE ABAY DISTRICT OF THE ABAY REGION, WHO ARE DESCENDANTS OF PERSONS EXPOSED TO RADIATION DUE TO NUCLEAR WEAPONS TESTS
2025 жыл | Шығарылым: 5 | Беттер: 32-39
TRENDS AND DISPARITIES IN CANCER MORBIDITY IN KAZAKHSTAN: A REGIONAL AND AGE-BASED ANALYSIS FOR 2014-2024
2025 жыл | Шығарылым: 5 | Беттер: 40-46
PATIENTS’ PERCEPTIONS OF THE QUALITY AND ACCESSIBILITY OF REHABILITATION SERVICES FOR LUNG CANCER: A CROSS-SECTIONAL STUDY
2025 жыл | Шығарылым: 5 | Беттер: 47-55
COMPARATIVE ANALYSIS OF COMPUTER TOMOGRAPHIC STAGING AND POSTOPERATIVE PATHOMORPHOLOGICAL STAGING IN STOMACH CANCER
2025 жыл | Шығарылым: 5 | Беттер: 56-62
COMMENTS ON 2016 EUROPEAN GUIDELINES FOR THE MANAGEMENT OF ATRIAL FIBRILLATION: NEW ASPECTS FOR PHYSICIANS
Updated European guidelines for the management of atrial fibrillation were published on the 27 of August, 2016. This document is remarkable for new recommendations, especially about anticoagulation therapy. Key points of these guidelines and the possibility of their use in our country are described in the article.
Objective: to find out essential evidence-based key points of the 2016 guidelines and to investigate the possibility of their use in Kazakhstan.
Materials and methods: To achieve these goals major differences between 2016, 2012, 2010 guidelines were analyze... Толығырақ
Objective: to find out essential evidence-based key points of the 2016 guidelines and to investigate the possibility of their use in Kazakhstan.
Materials and methods: To achieve these goals major differences between 2016, 2012, 2010 guidelines were analyze... Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 74-86
IMMUNOHISTOCHEMICAL ANALYSIS EXPRESSION TP73 IN ONCOCYTIC FOLLICULAR ADENOMA OF THE THYROID
Oncocytic follicular adenomas (FAs) of the thyroid are cells neoplasms of follicular origin that predominantly consist of large polygonal cells with eosinophilic and granular cytoplasm. According to some scientific studies, TP73 might play a сertain role in tumor genesis (oncogenesis). Moreover, due to the absence of p53, oncogenes may attract p73 to induce apoptosis in tumor cells. TP53 is a crucial tumor suppressor in preventing the cancerous transformation of cells. There was also a particular focus on the amplification of 1p36 chromosome in oncocytic FA, which contains a t...
Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 64-73
ASSESSMENT OF TOXICITY OF NEOADJUVANT CHEMOTHERAPY FOR LOCALLY ADVANCED BREAST CANCER
Introduction. In the structure of malignancies in women breast cancer (BC) takes 1st place. In locally advanced breast cancer (LABC) treatment begins with neoadjuvant chemotherapy (CTX), the standard protocols are CMF, FAC, AC. In the trial, we used cytostatic Arglabin isolated from plants endemic to Central Kazakhstan - wormwood smooth, as monotherapy and as addition to AC-protocol.
The objective of the trial - to assess the toxicity of different protocols of neoadjuvant CTX of LABC.
Methods: 93 patients with LABC (T2N1-2M0, T3N0-2M0) ... Толығырақ
The objective of the trial - to assess the toxicity of different protocols of neoadjuvant CTX of LABC.
Methods: 93 patients with LABC (T2N1-2M0, T3N0-2M0) ... Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 52-63
CLINICAL EVALUATION OF THE EFFICIENCY OF ORTHOPEDIC TREATMENT OF PATIENTS WITH EDENTULOUS JAWS WITH COMPLETE REMOVABLE DENTURES USING C-SILICONE MATERIALS FOR FUNCTIONAL IMPRESSIONS
Introduction. Prosthetics of edentulous jaw is one of the most difficult sections of prosthetic dentistry for many years. The difficulty lies in the production of functionally effective complete dentures that are in direct proportion to their fixation on the jaws, stabilization during chewing and even distribution of pressure on the underlying tissues.
The aim of this research was to conduct a comparative clinical evaluation of the efficiency of the complete removable laminar dentures that were made with use of the new materials for functional impressions.
Methods. At... Толығырақ
The aim of this research was to conduct a comparative clinical evaluation of the efficiency of the complete removable laminar dentures that were made with use of the new materials for functional impressions.
Methods. At... Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 37-51
CORRELATION ANALYSIS OF DATA USING STATISTICA AND SPSS SOFTWARE
In this paper we present the main principles of correlation analysis using parametric and non-parametric methods. Algorithms for calculations of Pearson’s, Spearmen’s and Kendall’s coefficients using Statistica 10 and SPSS 20 software are presented. Special emphasis is given to interpretation of results of statistical analysis. The article complements, but does not substitute specialized literature on biostatistics and clinical epidemiology.
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2017 жыл | Шығарылым: 1 | Беттер: 7-36