ФАКТОРЫ, ВЛИЯЮЩИЕ НА ОДНОЛЕТНЮЮ ВЫЖИВАЕМОСТЬ ПАЦИЕНТОВ ПОСЛЕ ИНСУЛЬТА В КАЗАХСТАНЕ: КОГОРТНОЕ ИССЛЕДОВАНИЕ
Введение. Существует много нерешенных вопросов относительно предикторов исхода мозгового инсульта (МИ). В литературе имеется единичные публикации по детерминантам исхода МИ в Казахстане, несмотря на высокую распространенность проблемы.
Целью настоящего исследования являлось оценка влияния факторов риска на выживаемость больных с инсультом в течение года в популяции г. Семей.
Методы. В когортное исследование были включены все случаи МИ в г. Семей с 01.01.2014г. до 31.12.15г. (n=937). Выживаемость больных с МИ оценивалась с помощью метода Kaплана-Mайера с определение... Толығырақ
Целью настоящего исследования являлось оценка влияния факторов риска на выживаемость больных с инсультом в течение года в популяции г. Семей.
Методы. В когортное исследование были включены все случаи МИ в г. Семей с 01.01.2014г. до 31.12.15г. (n=937). Выживаемость больных с МИ оценивалась с помощью метода Kaплана-Mайера с определение... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 46-57
ПОЛИМОРФИЗМ ГЕНА ИЛ10 В ПОЛОЖЕНИИ -1082G/A У БОЛЬНЫХ РОЖЕЙ
Целью данного исследования является выявление связи полиморфизма гена ИЛ10-1082 GA (rs1800896) с заболеванием рожей у лиц казахской национальности.
Материалы и методы: Полиморфизм гена ИЛ10-1082 GA изучен у 206 больных рожей и 422 лиц контрольной группы. Из них у 143 больных первичной рожей и 63 больных рецидиврующей рожей. Для генотипирования были выделены геномная ДНК из крови. Генотипирование проводили методом полимеразной цепной реакции в режиме реал-тайм. Для статистической обработки использовались критерий χ2Пирсона и отношение шансов (ОШ) с 95% доверительными ... Толығырақ
Материалы и методы: Полиморфизм гена ИЛ10-1082 GA изучен у 206 больных рожей и 422 лиц контрольной группы. Из них у 143 больных первичной рожей и 63 больных рецидиврующей рожей. Для генотипирования были выделены геномная ДНК из крови. Генотипирование проводили методом полимеразной цепной реакции в режиме реал-тайм. Для статистической обработки использовались критерий χ2Пирсона и отношение шансов (ОШ) с 95% доверительными ... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 34-45
ИЗМЕНЕНИЯ В ПЛАЗМЕ ТРИЙОДТИРОНИНА, ТИРОКСИНА И ТИРЕОТРОПНОГО ГОРМОНА ПОСЛЕ ОБЛУЧЕНИЯ 131 I У НОВОРОЖДЕННЫХ КРЫС, СОДЕРЖАВШИХСЯ НА ЙОДОДЕФИЦИТНОМ ПИТАНИИ
Background: Human thyroid gland is generally regarded as a relatively low-risk organ in terms of developing radiation-induced tumorigenesis. However, a rapid increase in the incidents of thyroid cancer after the Chernobyl nuclear reactor accident in 1986 provided additional insight into the risk of thyroid cancer. Three key risk factors have been identified to be involved in this increase: (1) internal irradiation from 131I fallout, (2) young age, and (3) a low-iodine diet. Our previous study demonstrated that the thyroid radiation dose was highest in the newborn rats f...
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2016 жыл | Шығарылым: 3 | Беттер: 26-33
СРАВНЕНИЕ КОЛИЧЕСТВЕННЫХ ДАННЫХ ДВУХ ПАРНЫХ ВЫБОРОК С ИСПОЛЬЗОВАНИЕМ ПРОГРАММНОГО ОБЕСПЕЧЕНИЯ STATISTICA И SPSS: ПАРАМЕТРИЧЕСКИЕ И НЕПАРАМЕТРИЧЕСКИЕ КРИТЕРИИ
В настоящей работе представлены общие сведения об использовании парного критерия Стьюдента, непараметрического критерия Вилкоксона и критерия знаков для сравнения количественных признаков парных выборок. Описан алгоритм расчета данных критериев с использованием программного обеспечения Statistica 10 и SPSS 20 и представлена интерпретация результатов расчетов. Настоящая статья призвана дать общие сведения об использовании парного критерия Стьюдента, парного критерия Вилкоксона и критерия знаков, и не заменяет прочтения специализированной литературы по статистике и клинической эпидемиологии.
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2016 жыл | Шығарылым: 3 | Беттер: 5-25
СРАВНИТЕЛЬНЫЙ АНАЛИЗ РАСПРЕДЕЛЕНИЯ РАБОЧЕГО ВРЕМЕНИ У СОТРУДНИКОВ ОТДЕЛЕНИЙ ХИРУРГИЧЕСКОГО ПРОФИЛЯ ПРИ ИСПОЛЬЗОВАНИИ МЕДИЦИНСКОЙ ИНФОРМАЦИОННОЙ СИСТЕМЫ
2016 жыл | Шығарылым: 2 | Беттер: 150-161
COMPARATIVE EVALUATION OF BLOOD COLLECTION TUBES AND EXTRACTION METHODS FOR CIRCULATING TUMOR DNA
2025 жыл | Шығарылым: 6 | Беттер: 7-13
INFLUENCE OF SEX HORMONE-BINDING GLOBULIN (SHBG) ON THE LEVEL OF FREE TESTOSTERONE FRACTION IN OLDER OVERWEIGHT MEN
2025 жыл | Шығарылым: 6 | Беттер: 14-20
ASSESSMENT OF THE PROBABILITY OF DEVELOPING CARDIORENAL SYNDROME TYPE 2 DEPENDING ON POTENTIAL BIOMARKERS IN PEDIATRIC PATIENTS
2025 жыл | Шығарылым: 6 | Беттер: 21-29
MORPHO-GENETIC VARIABILITY IN MYOCARDIAL TISSUE AFTER SEPTAL MYECTOMY IN PATIENTS WITH OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY: A FOUR-CASE SERIES STUDY
2025 жыл | Шығарылым: 6 | Беттер: 30-37
CLINICAL EFFICACY OF SELECTIVE PLASMA FILTRATION (EVACLIO) IN CARDIOVASCULAR COMPLICATIONS: A CASE SERIES FROM THE HEART CENTER KAZAKHSTAN
2025 жыл | Шығарылым: 6 | Беттер: 38-46
CLINICAL - ORIENTED TECHNOLOGIES OF QUALITY ASSURANCE ORTHOPEDIC TREATMENT: COMPARATIVE EVALUATION PHYSICAL AND MECHANICAL PROPERTIES OF ACRYLIC PLASTICS POLYMERIZED WITH COLD TEMPREATURE
Introduction. Plastics of cold polymerization are using in dentistry to repair (rebase) dentures, repair of prostheses, the manufacture of temporary prostheses, tires on parodontal diseases, models, and other.
Manufacturer of removable prosthesis consists of many stages. The first is impression, after that there will be some technological stages in the dental laboratory. These includes obtaining the model, setting the teeth, making a wax model, making gypsum model in the dental ditch and removing, decoction of wax, and then filling the resulting space with forming material for th... Толығырақ
Manufacturer of removable prosthesis consists of many stages. The first is impression, after that there will be some technological stages in the dental laboratory. These includes obtaining the model, setting the teeth, making a wax model, making gypsum model in the dental ditch and removing, decoction of wax, and then filling the resulting space with forming material for th... Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 60-71
THE MODERN VIEW PREMATURE BIRTH
Premature birth is one of the topical problems in obstetrics and gynecology, also in perinatology, because premature infants account 60-70% of perinatal illness and mortality. But many aspects of premature birth problem is debatable and need further research. Using in full volume the known methods of research’s diagnostic opportunities and new medicine technologies will help to resolve this problem.
Despite the wide range of existing prediction methods, the presence of the selected biomarkers sensitivity used in this test time is not high enough and in the order 40-60%, so about ... Толығырақ
Despite the wide range of existing prediction methods, the presence of the selected biomarkers sensitivity used in this test time is not high enough and in the order 40-60%, so about ... Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 39-49
MORPHOLOGICAL CHANGES INDUSED LUNG IINDUSTRIAL CHRYSOTILE FREE OF DUST
The respiratory organs directly interact with atmospheric air and this fact leads to the penetration of such harmful substances as gaseous fluid, fog, smoke, dust and aerosols into the lungs. And dust is the most harmful factor of the air pollution in the contemporary industrial production and the development of subsequent of the pulmonary dysfunction.
The morphological method of studying of the bronchial - pulmonary system is one of the basic criteria of evaluation of pathogenic properties of above-mentioned harmful substances. The method out is applied during the hygienic rate-setting ... Толығырақ
The morphological method of studying of the bronchial - pulmonary system is one of the basic criteria of evaluation of pathogenic properties of above-mentioned harmful substances. The method out is applied during the hygienic rate-setting ... Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 30-38
THE MODERN UNDERSTANDING OF THE MOLECULAR MECHANISMS OF METFORMIN ACTION
There view deals with the analysis of the molecular
mechanism of the effect of metformin, the antidiabetic drug widely applied all
over the world. In addition to the hypoglycemic effect, metformin was
discovered to have several pleiotropic actions, particularly antitumor. The
effect of metformin on proliferation of cancer cells is related to activation
of AMP-sensitive kinase and suppression of mTOR, which plays an
important role in regulation of cellular growth. Glucose drop by metformin was
caused by its ability to suppress gluconeogenesis in liver t... Толығырақ
mechanism of the effect of metformin, the antidiabetic drug widely applied all
over the world. In addition to the hypoglycemic effect, metformin was
discovered to have several pleiotropic actions, particularly antitumor. The
effect of metformin on proliferation of cancer cells is related to activation
of AMP-sensitive kinase and suppression of mTOR, which plays an
important role in regulation of cellular growth. Glucose drop by metformin was
caused by its ability to suppress gluconeogenesis in liver t... Толығырақ
2015 жыл | Шығарылым: 2 | Беттер: 19-29
CROSS-SECTIONAL STUDIES IN HEALTH SCIENCES
In this paper we present basic principles of planning and carrying out cross-sectional studies in health sciences as well as analyzing the data collected in these studies. We present practical examples of sample size and effect measures calculation for cross-sectional studies using online calculators and Epi Info software. Examples of studies using cross-sectional design from international peer-reviewed literature are also presented. This article provides general introduction to cross-sectional studies and does not substitute specialized literature in clinical epidemiology.
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2015 жыл | Шығарылым: 2 | Беттер: 5-18