Online ISSN: 3007-0244,
Print ISSN:  2410-4280
Фильтр
Автор(ы):
  
ФАКТОРЫ, ВЛИЯЮЩИЕ НА ОДНОЛЕТНЮЮ ВЫЖИВАЕМОСТЬ ПАЦИЕНТОВ ПОСЛЕ ИНСУЛЬТА В КАЗАХСТАНЕ: КОГОРТНОЕ ИССЛЕДОВАНИЕ
Введение. Существует много нерешенных вопросов относительно предикторов исхода мозгового инсульта (МИ). В литературе имеется единичные публикации по детерминантам исхода МИ в Казахстане, несмотря на высокую распространенность проблемы.
Целью настоящего исследования являлось оценка влияния факторов риска на выживаемость больных с инсультом в течение года в популяции г. Семей.
Методы. В когортное исследование были включены все случаи МИ в г. Семей с 01.01.2014г. до 31.12.15г. (n=937). Выживаемость больных с МИ оценивалась с помощью метода Kaплана-Mайера с определение...
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 46-57

ПОЛИМОРФИЗМ ГЕНА ИЛ10 В ПОЛОЖЕНИИ -1082G/A У БОЛЬНЫХ РОЖЕЙ
Целью данного исследования является выявление связи полиморфизма гена ИЛ10-1082 GA (rs1800896) с заболеванием рожей у лиц казахской национальности.
Материалы и методы: Полиморфизм гена ИЛ10-1082 GA изучен у 206 больных рожей и 422 лиц контрольной группы. Из них у 143 больных первичной рожей и 63 больных рецидиврующей рожей. Для генотипирования были выделены геномная ДНК из крови. Генотипирование проводили методом полимеразной цепной реакции в режиме реал-тайм. Для статистической обработки использовались критерий χ2Пирсона и отношение шансов (ОШ) с 95% доверительными ...
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 34-45

ИЗМЕНЕНИЯ В ПЛАЗМЕ ТРИЙОДТИРОНИНА, ТИРОКСИНА И ТИРЕОТРОПНОГО ГОРМОНА ПОСЛЕ ОБЛУЧЕНИЯ 131 I У НОВОРОЖДЕННЫХ КРЫС, СОДЕРЖАВШИХСЯ НА ЙОДОДЕФИЦИТНОМ ПИТАНИИ
Background: Human thyroid gland is generally regarded as a relatively low-risk organ in terms of developing radiation-induced tumorigenesis. However, a rapid increase in the incidents of thyroid cancer after the Chernobyl nuclear reactor accident in 1986 provided additional insight into the risk of thyroid cancer. Three key risk factors have been identified to be involved in this increase: (1) internal irradiation from 131I fallout, (2) young age, and (3) a low-iodine diet. Our previous study demonstrated that the thyroid radiation dose was highest in the newborn rats f...
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 26-33

СРАВНЕНИЕ КОЛИЧЕСТВЕННЫХ ДАННЫХ ДВУХ ПАРНЫХ ВЫБОРОК С ИСПОЛЬЗОВАНИЕМ ПРОГРАММНОГО ОБЕСПЕЧЕНИЯ STATISTICA И SPSS: ПАРАМЕТРИЧЕСКИЕ И НЕПАРАМЕТРИЧЕСКИЕ КРИТЕРИИ
В настоящей работе представлены общие сведения об использовании парного критерия Стьюдента, непараметрического критерия Вилкоксона и критерия знаков для сравнения количественных признаков парных выборок. Описан алгоритм расчета данных критериев с использованием программного обеспечения Statistica 10 и SPSS 20 и представлена интерпретация результатов расчетов. Настоящая статья призвана дать общие сведения об использовании парного критерия Стьюдента, парного критерия Вилкоксона и критерия знаков, и не заменяет прочтения специализированной литературы по статистике и клинической эпидемиологии.
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 5-25

PROSPECTS FOR CORRECTION OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH PANCREATIC CANCER
Автор (лар): Олжаев С.Т.
The subject of the research is the functional indicators of the vascular endothelium in patients with pancreatic cancer.
Purpose of the study. Determining the results of the correction of disorders of the vascular endothelium in patients with pancreatic cancer after surgery.
Materials and methods. Study design: A prospective, randomized clinical trial. 95 patients with pancreatic head cancer (T3N0M0 (2a), T1-3N1M0 (2b) or T4N1M0) were examined, including 52 men and 43 women, the average age in the group was 61.7 ± 2.1 years. For the correction of the state o...
Толығырақ
2018 жыл | Шығарылым: 6 | Беттер: 108-113

ANALYSIS OF RADIATION REACTIONS OF SKIN AFTER HYPOFRACTIONATED RADIATION THERAPY OF BREAST CANCER
Background:  In the Republic of Kazakhstan, breast cancer takes a leading position among all malignant neoplasms in women. Radiation therapy is a standard and obligatory component of complex treatment of breast cancer. Daily fractions use of 2 Gy to a total focal dose of 50 Gy is the traditional standard scheme for radiotherapy treatment.  However, due to the increase in the number of detected diseases at an early stage, approaches to the treatment of breast cancer have changed in recent years. Acute radiation skin reactions are one of the most frequent side effects of this...
Толығырақ
2018 жыл | Шығарылым: 6 | Беттер: 114-120

ORGANIZATION ASPECTS OF THE PALLIATIVE CARE SYSTEM FOR CANCER PATIENTS BASED ON THE OPINION OF RELATIVES AND CLOSEST INCURABLE PATIENTS
neoplasms. Kazakhstan is in its infancy a palliative care service for oncology patients. The lack of rehabilitation assistance significantly worsens the quality of life of patients. In this regard, it is supposed to constantly improve the professional level of specialists in the field of rehabilitation, prevention and palliative care for patients with malignant tumors. Today, patients with malignant neoplasms undergo medical and social rehabilitation. The absence of the psychological and social aspects mentioned above also indicates that these conditions are resolved separately from medical in...
Толығырақ
2018 жыл | Шығарылым: 6 | Беттер: 121-130

PARKINSON'S DISEASE AND THE PROBLEMS OF TREATMENT OF TREATED STATIONARY CASES IN THE STATE MEDICAL UNIVERSITY HOSPITAL OF SEMEY FOR 2013-2018
Relevance: The article presents the main problems that a doctor encounters in the neurology department during diagnosis and treatment of Parkinson's disease. Parkinson's disease (PD) is a chronic progressive neurodegenerative disease, the incidence of which is steadily increasing. The notion of PD as an exclusively purely motor disorder has undergone significant changes.
Purpose: The goal was to analyze the clinical and diagnostic approaches of treated cases of PD and the basic inpatient treatment scheme for this pathology, as well as to identify existing problems of tre...
Толығырақ
2018 жыл | Шығарылым: 6 | Беттер: 131-137

THE OPTIMIZATION OF TREATMENT OF ESSENCIAL ARTERIAL HYPERTENSION IN EAST KAZAKHSTAN
Introduction.Despite the successes achieved in the treatment of essential hypertension (AH), the problem of treatment of resistant hypertension remains urgent.
In this regard, in many countries around the world, innovative non-drug method of sympathetic denervation of renal arteries using high frequency currents has been widely spread.
Aim. To determine efficacy of sympathetic denervation of renal arteries for the course of resistant hypertension according to the materials of the cardiological department of the University Hospital.
Materials and methods. 86 patients ...
Толығырақ
2018 жыл | Шығарылым: 6 | Беттер: 138-142