Online ISSN: 3007-0244,
Print ISSN:  2410-4280
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ОТДАЛЕННЫЕ ЭФФЕКТЫ РАЗНОЙ ДОЗЫ ГАММА-ИЗЛУЧЕНИЯ НА ЛИМФОИДНЫЕ ОРГАНЫ ИММУНОГЕНЕЗА
В отдаленном периоде после сублетального и фракционированного действия гамма-излучения в тимусе и лим-фатических узлах тонкого кишечника снижены количества лимфоидных клеток. В тимусе и селезенке определяется атрофия, в лимфатических узлах тонкого кишечника  - сниженный лимфоидный индекс и лимфоидных клеток.
В отдаленном периоде после воздействия малой дозы гамма-излучения отмечается атрофия тимуса и перерас-пределение лимфоидных клеток из тимуса и лимфатических узлов тонкого кишечника в костный мозг и селезенку.
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 49-53

DENTAL STATUS OF PATIENTS DURING THE SUPPORTIVE CARE AT ANTINEOPLASTIC CHEMOTHERAPY FOR BREAST CANCER
Автор (лар): Сухина И.С.
Two groups were studied in a comparative aspect – 98 women with breast cancer during the courses of adjuvant chemo-therapy: the first was comprised of 26 patients who used their conventional means for oral hygiene; the second included 72 patients, who received the complex of therapeutic and preventive measures of supportive care. Dental toxicity was observed in 84.6-96.2 %, and has grown with the increase of the cycles of chemotherapy, reaching a maximum value on the V cycle of treatment. It is shown that the application of the developed complex significantly reduces the manifestations of ...
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 35-39

ДАННЫЕ СКРИНИНГА ПАТОЛОГИИ ЩИТОВИДНОЙ ЖЕЛЕЗЫ У ЖИТЕЛЕЙ РАЙОНОВ, ПОДВЕРГШИХСЯ РАДИАЦИОННОМУ ОБЛУЧЕНИЮ
В статье приведены данные, полученные в результате скрининга населения районов, подвергшихся радиационному облучению. Целью исследования было выявление  частоты и особенностей патологии щитовидной железы у жителей районов Павлодарской и Восточно-Казахстанской областей, подвергшиеся радиационному облучению. Обследовано 1783 человека. Диффузный эутиреоидный зоб диагностирован в 32,97% случаев, колло-идно-узловой зоб у 13,60% обследованных, аутоиммуный тиреоидит у 52,96%, в 2,4% случаев наблюдался много-узловой зоб. Анализ функционального состояния щитовидной железы пока...
Толығырақ
2014 жыл | Шығарылым: 3 | Беттер: 22-25

МОДЕЛИРОВАНИЕ САХАРНОГО ДИАБЕТА 2 ТИПА ДЛЯ ИЗУЧЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ С АНТИДИАБЕТИЧЕСКОЙ АКТИВНОСТЬЮ
Учитывая неуклонно возрастающее  во всем мире число больных сахарным диабетом 2 типа, актуальной проблемой современной фармакологии продолжает оставаться разработка антидиабетических препаратов, обладающих высокой терапевтической активностью и имеющих более совершенный профиль безопасности. В связи с этим важное значение имеет моделирование сахарного диабета, позволяющее достоверно выявлять наличие той или иной фармакологической активности или новых деталей в  механизме действия лекарственных средств. Модели сахарного диабета могут быть получены на различных видах животных ...
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 4-8

ТЯЖЕЛОЕ ОБОСТРЕНИЕ БРОНХИАЛЬНОЙ АСТМЫ. ДИАГНОСТИКА, ЛЕЧЕНИЕ. (Лекция)
Обострение бронхиальной астмы (БА) - это прогрессирующее увеличение эпизодов кашля, одышки, появления хрипов, одышки, ощущения одышки или различных сочетаний этих симптомов [7,11].
Лечение  астмы зависит от пациента, опыта медицинского персонала, от наиболее эффективного лечения для каждого отдельного пациента, наличия лекарств и наличия оборудования для неотложной медицинской помощи [15,22].
Основой лечения  астмы являются многократное назначение быстро вдыхаемого b2-агониста или комбинации быстродействующего вдыхаемого b2-агониста и антихолинергическог...
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 9-12

COMBINATIONS OF CONGENITAL HEART DISEASES AND A CONNECTIVE TISSUE DYSPLASIA AMONG CHILDREN OF SEMEY
Introduction. There is evidence on common mechanisms of congenital heart diseases (CHD) and connective tissue dysplasia (CTD), which increases odds for their comorbidities. The latter may be associated with poorer prognosis for CHD. However, the associations between CHD and CTD in Kazakhstan have been poorly studied so far.
Aim – to assess the frequency of CTD signs in children with CHD living in Semey, Kazakhstan.
Materials and methods. We examined 168 children aged 1 to14 years, including 84 – with CHD and 80 children with no signs of CHD.
Associations betw...
Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 101-110

CAUSES OF REFUSING MEDICAL EXAMINATIONBY PATIENTS WITH SUSPECTED CANCER AS PERCEIVED BY PRIMARY CARE PHYSICIANS IN SOUTH KAZAKHSTAN REGION
Objective: To identify the most frequent causes of refusing thorough medical examinations by patients with suspected cancer as perceived by primary care physicians in South Kazakhstan Region (SKR).
Methods: We performed a cross-sectional study, which included 500 primary care physicians in SKR. Data collection took place between 01 January 2016 and 14 April 2016). The questionnaire contained 33 semi-open questions. Filling out time was between 20 and 25 minutes. Only doctors who worked at policlinics during the time of the study were included. Results are presented absolute n...
Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 90-100

IMPACT OF ERYTHROCYTES ANTIGENS ON DEVELOPMENT OF LIVER CIRRHOSIS
Introduction. High rates of prevalence and mortality of liver cirrhosis, it’s late clinical manifestation, disadvantages of liver biopsy highlight the background points of our research.
Aim. Research of erythrocytes’ antigens profile in patients with liver cirrhosis of Kazakh and Russian ethnical groups.
Materials and Methods: One hundred and forty patients with liver cirrhosis and 272 relatively healthy participants of both of nationalities were involved into research. АВ0, MNS, P1, CDE systems of erythrocytes of venous blood were investigated. For the comparison of the frequenc...
Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 80-89

PSYCHOTHERAPEUTIC REHABILITATION AND NORMALIZATION OF PSYCHOEMOTIONAL AND FUNCTIONAL CONDITION OF PATIENTS WITH PAIN SYNDROMES IN BRAIN ORGANIC LESIONS
Background. Psychoemotional violations impede adequate recovery of neurological function in patients with pain syndromes on a background of central nervous system, enhance their social and domestic roles, as well as substantially reduce the quality of life in patients.
Aim: to increase the efficiency of the rehabilitation of patients with pain syndromes on a background of organic defeat CNS.
Methods. The study has a prospective, comparative open character. The results of psychological rehabilitation were analyzed in 500 patients with stroke, head injury and suffering pain syndromes...
Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 64-79

RNA SEQUENCING OF SQUAMOUS ESOPHAGEAL CANCER: FROM THE COLLECTION OF THE BIOMATERIAL UNTIL SEQUENCING ON HISEQ2000
The squamous esophageal cancer is a disease which is highly frequent in Kazakhstan, the frequency of the disease is 10,1:100 000. In the mortality structure esophageal cancer takes place among men the 5th place, among women the 9th place in the Republic of Kazakhstan. The molecular mechanisms which contribute to the initiation and progression of the cancer pathology are not investigated enough. Nevertheless, the lack of the sensitive and specific biomarkers for the diagnosis of the cancer diseases, underlines about the necessity of the additional research works to study about the development o...
Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 53-63