ПРИМЕНЕНИЕ ФРОМИЛИДА УНО ПРИ ОСТРОЙ ВНЕБОЛЬНИЧНОЙ ПНЕВМОНИИ
Под наблюдением находилось 60 больных с острой внебольничной пневмонией, в возрасте от 32 до 67 лет. Средний возраст составил 46, 2 года. Первую группу составили 30 больных, получали с антибактериальной целью препарат Фромилид УНО в дозе 500 мг 1т х 2р в день в течении 10 дней. Вторую группу составили 30 больных, полу-чали цефазолин 1,0 х 2р в/м в течении 10 дней. Под влиянием терапии отмечали положительную динамику показа-телей в обеих группах, но более выраженную в первой группе. Фромилид УНО оказывает выраженный антибактери-альный эффект.
Толығырақ
2014 жыл | Шығарылым: 1 | Беттер: 59-61
ПРОБЛЕМА АНТИБИОТИКОРЕЗИСТЕНТНОСТИ ОСНОВНЫХ ВОЗБУДИТЕЛЕЙ ВНЕБОЛЬНИЧНОЙ ПНЕВМОНИИ И ПУТИ ЕЕ ПРЕОДОЛЕНИЯ
В статье представлены результаты бактериологического исследования мокроты и определения чувствительности возбудителей внебольничной пневмонии у пациентов пульмонологического отделения. Описаны причины развития антибиотикорезистентности и современные методы комбинированной антибиотикотерапии внебольничной пневмонии.
Толығырақ
2014 жыл | Шығарылым: 1 | Беттер: 57-59
ЭФФЕКТИВНОСТЬ ПРИМЕНЕНИЯ ФРОМИЛИД УНО ПРИ ИНФЕКЦИЯХ ВЕРХНИХ И НИЖНИХ ДЫХАТЕЛЬНЫХ ПУТЕЙ
Длительный опыт клинического использования свидетельствует о том, что Фромилид УНО (кларитромицин) за-нимает одно из важных мест в терапии острых и хронических инфекций верхних и нижних дыхательных путей и ак-туальность его применения возрастает с получением новых сведений об эффектах этого антибактериального пре-парата. Подтверждена высокая эффективность и безопасность препарата Фромилид УНО при лечении пациентов с острыми и хроническими инфекционно-воспалительными заболеваниями верхних и нижних дыхательных путей. Дозирование препарата один раз в сутки создает высокий комплаенс, миним...
Толығырақ
2014 жыл | Шығарылым: 1 | Беттер: 55-57
ЭФФЕКТИВНОСТЬ ЛЕЧЕНИЯ НОВЫХ СЛУЧАЕВ ТУБЕРКУЛЕЗА ОРГАНОВ ДЫХАНИЯ
В статье проанализированы основные причины низкой эффективности лечения впервые выявленных больных. Невыполнение протокола диагностического алгоритма общей лечебной сетью привело к распространенным процес-сам, явившимся причиной смерти в 5 (2,8%) случаях. Поздняя обращаемость населения за медицинской помощью и высокий показатель МЛУ ТБ составил 13,7%.
Толығырақ
2014 жыл | Шығарылым: 1 | Беттер: 53-54
ВЫДЕЛЕНИЕ И ОЧИСТКА НУКЛЕИНОВЫХ КИСЛОТ. СОСТОЯНИЕ ПРОБЛЕМЫ НА СОВРЕМЕННОМ ЭТАПЕ
В статье представлены стандартные и инновационные методы выделения ДНК, указаны преимущества и недо-статки различных способов экстракции ДНК. Описана качественная и количественная оценка нуклеиновых кислот для получения наиболее полноценной ДНК, позволяющая потом ее использовать в широком диапазоне научных исследований.
Толығырақ
2014 жыл | Шығарылым: 1 | Беттер: 51-53
COMPARATIVE EVALUATION OF BLOOD COLLECTION TUBES AND EXTRACTION METHODS FOR CIRCULATING TUMOR DNA
2025 жыл | Шығарылым: 6 | Беттер: 7-13
INFLUENCE OF SEX HORMONE-BINDING GLOBULIN (SHBG) ON THE LEVEL OF FREE TESTOSTERONE FRACTION IN OLDER OVERWEIGHT MEN
2025 жыл | Шығарылым: 6 | Беттер: 14-20
ASSESSMENT OF THE PROBABILITY OF DEVELOPING CARDIORENAL SYNDROME TYPE 2 DEPENDING ON POTENTIAL BIOMARKERS IN PEDIATRIC PATIENTS
2025 жыл | Шығарылым: 6 | Беттер: 21-29
MORPHO-GENETIC VARIABILITY IN MYOCARDIAL TISSUE AFTER SEPTAL MYECTOMY IN PATIENTS WITH OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY: A FOUR-CASE SERIES STUDY
2025 жыл | Шығарылым: 6 | Беттер: 30-37
CLINICAL EFFICACY OF SELECTIVE PLASMA FILTRATION (EVACLIO) IN CARDIOVASCULAR COMPLICATIONS: A CASE SERIES FROM THE HEART CENTER KAZAKHSTAN
2025 жыл | Шығарылым: 6 | Беттер: 38-46
RNA SEQUENCING OF SQUAMOUS ESOPHAGEAL CANCER: FROM THE COLLECTION OF THE BIOMATERIAL UNTIL SEQUENCING ON HISEQ2000
The squamous esophageal cancer is a disease which is highly frequent in Kazakhstan, the frequency of the disease is 10,1:100 000. In the mortality structure esophageal cancer takes place among men the 5th place, among women the 9th place in the Republic of Kazakhstan. The molecular mechanisms which contribute to the initiation and progression of the cancer pathology are not investigated enough. Nevertheless, the lack of the sensitive and specific biomarkers for the diagnosis of the cancer diseases, underlines about the necessity of the additional research works to study about the development o...
Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 53-63
DEVELOPMENT OF HALOPLEX PANEL AND PREPARATION OF DNA LIBRARIES FOR TARGETED SEQUENCING OF CARDIAC ARRHYTHMIAS
Method of preparation of custom HaloPlex cardiogenetic panel (Agilent Technologies) and method of preparation of DNA libraries for targeted sequencing of 96 genes associated with cardiac arrhythmias were described in details in this article. SureDesign Online Design software (Agilent Technologies) was used to create the HaloPlex panel. Final design was developed for Illumina platform using Human Genome version 19, GRCh 37. 19958 amplicons were generated by the program, 99,46% of all target regions were covered successfully. DNA libraries were prepared for 48 samples using t...
Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 43-52
DETERMINATION OF GENETIC VARIANTS ASSOCIATED WITH HYPERTENSION, OBESITY AND DIABETES IN KAZAKH POPULATION TO STUDY INTERACTION OF GENETIC VARIANTS AND METABOLOME
In this work genetic variants associated with hypertension, obesity and diabetes were characterized, and genomic data of 60 samples were compared using Т-HOD (The Text-mined Hypertension, Obesity and Diabetes candidate gene database (T-HOD) international database.
Genetic variants extracted from whole genomes and exomes, and associated with hypertension, obesity and diabetes based on PolyPhen2 and SIFT algorithmic predictors of mutation pathogenicity were analyzed. Seven genetic variants were detected in GHRL (rs4684677), MTHFR (rs1801133), OPRM1 (rs17999... Толығырақ
Genetic variants extracted from whole genomes and exomes, and associated with hypertension, obesity and diabetes based on PolyPhen2 and SIFT algorithmic predictors of mutation pathogenicity were analyzed. Seven genetic variants were detected in GHRL (rs4684677), MTHFR (rs1801133), OPRM1 (rs17999... Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 30-42
REPORT ABOUT THE CONFERENCE: THE INTERNATIONAL WОRLD HEALTH ORGANIZATION CONSULTATION ON NUTRITION AND PREGNANCY (27-28 June 2016, RIGA, LATVIA)
27-28 June 2016, Riga, Latvia hosted the International WHO consultation on nutrition and pregnancy, with participation of experts in the field of maternal and child health and the WHO Collaborating Centers from Poland, Latvia, Lithuania, Estonia, Italy, the UK, Kazakhstan, Tajikistan, Uzbekistan, Kyrgyzstan, Georgia, Armenia and Moldova. The key problems of women's health and nutrition, according to speakers from different countries are the following: the growth of overweight and obesity among women, excessive weight gain during pregnancy, low rates of exclusive breastfeeding in the first ...
Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 166-172
MODERN LAVAGE OF THE GASTROINTESTINAL TRACT FROM THE PERSPECTIVE OF THE QUALITY OF DIAGNOSIS AND TREATMENT IN ENDOSCOPIC, BARIATRIC SURGERY (LITERATURE REVIEW)
Introduction. The issue of quality lavage for the gastrointestinal tract before an abdominal surgery and endoscopic examination is of paramount significance, especially in patients with visceral obesity.
The aim of the study is to study historical aspects of intestinal cleansing, identify optimal ways to lavage and define its tolerability by patients.
Research methods. The review examines the effectiveness of different lavage techniques and patients’ preparation before surgeries and endoscopic examinations. The analysis of 77 sources relevant to the results of the study is also inc... Толығырақ
The aim of the study is to study historical aspects of intestinal cleansing, identify optimal ways to lavage and define its tolerability by patients.
Research methods. The review examines the effectiveness of different lavage techniques and patients’ preparation before surgeries and endoscopic examinations. The analysis of 77 sources relevant to the results of the study is also inc... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 145-165