Online ISSN: 3007-0244,
Print ISSN:  2410-4280
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Автор(ы):
  
СЛУЧАЙ РАЗВИТИЯ ПРОГРЕССИРУЮЩЕЙ МУЛЬТИФОКАЛЬНОЙ ЛЕЙКОЭНЦЕФАЛОПАТИИ (ПМЛ) У БОЛЬНОГО С СОЧЕТАННОЙ ПАТОЛОГИЕЙ ВИЧ И ТУБЕРКУЛЕЗ
Автор (лар):
Продемонстрированный нами случай быстро прогрессирующей мультифокальной лейкоэнцефалопатии с ле-тальным исходом на фоне выраженного иммунодефицита у больного СПИДом, подтверждает необходимость свое-временной антиретровирусной терапии, как единственного способа профилактики данной патологии с неразрабо-танными методами специфической профилактики и этиотропного лечения.
Толығырақ
2013 жыл | Шығарылым: 1 | Беттер: 71-73

ЦЕНТРАЛЬНОЕ ВЕНОЗНОЕ ДАВЛЕНИЕ И МОРФОЛОГИЧЕСКИЕ ИЗМЕНЕНИЯ В ОРГАНАХ КРОЛИКОВ ПРИ ПРОВЕДЕНИИ ВНУТРИВЕННЫХ ИНФУЗИЙ
Проведен опыт на 27 здоровых кроликах. 22-м кроликам проводилась внутривенная инфузия физиологического раствора в разных объемах. У всех 27 кроликов брались гистологические микропрепараты органов: головной мозг, сердце, легкие, печень и почки. У всех кроликов выявлено исходное отрицательное центральное венозное давление (ЦВД) от -4,8±0,9 до -10,2±1,6 мм водного столба. Введение изотонического раствора в объеме от 100 до 700 мл привело к повышению ЦВД от исходного отрицательного до 183,3±7,9 мм водного столба. При морфологической оценке изменений в органах умерших кроликов выявлено, что...
Толығырақ
2013 жыл | Шығарылым: 1 | Беттер: 78-79

CENTRAL VENOUS PRESSURE AND MORPHOLOGICAL CHANGES IN ORGANS OF RABBITS AT INTRAVENOUS INFUSION
Experiment was performed on 27 healthy rabbits. To 22 rabbits the intravenous infusion of normal saline solution was done in different amounts. At all 27 rabbits the histology preparations were taken: brain, heart, lungs, liver and kidneys. All rabbits showed negative initial central venous pressure (CVP) from -4,8±0,9 to - 10,2±1,6 mm of water column. Infusion of isotonic solution in a volume of 100 to 700 ml resulted in increased CVP from the original negative to 183,3±7,9 mm of water column. At morphological assessment of changes in the organs of dead rabbits was found that the seve...
Толығырақ
2013 жыл | Шығарылым: 1 | Беттер: 78-79

COMMENTS ON 2016 EUROPEAN GUIDELINES FOR THE MANAGEMENT OF ATRIAL FIBRILLATION: NEW ASPECTS FOR PHYSICIANS
Автор (лар): Галимжанов А.М.
Updated European guidelines for the management of atrial fibrillation were published on the 27 of August, 2016. This document is remarkable for new recommendations, especially about anticoagulation therapy. Key points of these guidelines and the possibility of their use in our country are described in the article.

Objective: to find out essential evidence-based key points of the 2016 guidelines and to investigate the possibility of their use in Kazakhstan.

Materials and methods: To achieve these goals major differences between 2016, 2012, 2010 guidelines were analyze...
Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 74-86

IMMUNOHISTOCHEMICAL ANALYSIS EXPRESSION TP73 IN ONCOCYTIC FOLLICULAR ADENOMA OF THE THYROID
Автор (лар): Қoзыкенова Ж.У.
Oncocytic follicular adenomas (FAs) of the thyroid are cells neoplasms of follicular origin that predominantly consist of large polygonal cells with eosinophilic and granular cytoplasm. According to some scientific studies, TP73 might play a сertain role in tumor genesis (oncogenesis). Moreover, due to the absence of p53, oncogenes may attract p73 to induce apoptosis in tumor cells. TP53 is a crucial tumor suppressor in preventing the cancerous transformation of cells. There was also a particular focus on the amplification of 1p36 chromosome in oncocytic FA, which contains a t...
Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 64-73

ASSESSMENT OF TOXICITY OF NEOADJUVANT CHEMOTHERAPY FOR LOCALLY ADVANCED BREAST CANCER
Introduction. In the structure of malignancies in women breast cancer (BC) takes 1st place. In locally advanced breast cancer (LABC) treatment begins with neoadjuvant chemotherapy (CTX), the standard protocols are CMF, FAC, AC. In the trial, we used cytostatic Arglabin isolated from plants endemic to Central Kazakhstan - wormwood smooth, as monotherapy and as addition to AC-protocol.

The objective of the trial - to assess the toxicity of different protocols of neoadjuvant CTX of LABC.

Methods: 93 patients with LABC (T2N1-2M0, T3N0-2M0) ...
Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 52-63

CLINICAL EVALUATION OF THE EFFICIENCY OF ORTHOPEDIC TREATMENT OF PATIENTS WITH EDENTULOUS JAWS WITH COMPLETE REMOVABLE DENTURES USING C-SILICONE MATERIALS FOR FUNCTIONAL IMPRESSIONS
Introduction. Prosthetics of edentulous jaw is one of the most difficult sections of prosthetic dentistry for many years. The difficulty lies in the production of functionally effective complete dentures that are in direct proportion to their fixation on the jaws, stabilization during chewing and even distribution of pressure on the underlying tissues.

The aim of this research was to conduct a comparative clinical evaluation of the efficiency of the complete removable laminar dentures that were made with use of the new materials for functional impressions.

Methods. At...
Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 37-51

CORRELATION ANALYSIS OF DATA USING STATISTICA AND SPSS SOFTWARE
In this paper we present the main principles of correlation analysis using parametric and non-parametric methods. Algorithms for calculations of Pearson’s, Spearmen’s and Kendall’s coefficients using Statistica 10 and SPSS 20 software are presented. Special emphasis is given to interpretation of results of statistical analysis. The article complements, but does not substitute specialized literature on biostatistics and clinical epidemiology.
Толығырақ
2017 жыл | Шығарылым: 1 | Беттер: 7-36