АДАПТИВНАЯ КИНЕЗИТЕРАПИЯ В КОРРЕКЦИИ ДЕФЕКТОВ ПРОСТРАНСТВЕННОГО ОРИЕНТИРОВАНИЯ У ПОСТИНСУЛЬТНЫХ ПАЦИЕНТОВ
Целью исследования являлась разработка и клиническая апробация новой концепции персонализированной реабилитации пациентов, перенесших мозговой инсульт в раннем восстановительном периоде, основанной на количественной идентификации дефекта функции пространственного ориентирования.
Материалы и методы. В исследовании приняло участие 59 человек: группа контроля - 26 здоровых добровольцев, группа пациентов №1 получавших комплексное лечение с однотипной программой адаптивной кинезитерапии - 18 человек и группа пациентов №2 включала 15 лиц (возраст лиц в группе 62,7 [68,9/61,1] лет), по... Толығырақ
Материалы и методы. В исследовании приняло участие 59 человек: группа контроля - 26 здоровых добровольцев, группа пациентов №1 получавших комплексное лечение с однотипной программой адаптивной кинезитерапии - 18 человек и группа пациентов №2 включала 15 лиц (возраст лиц в группе 62,7 [68,9/61,1] лет), по... Толығырақ
2019 жыл | Шығарылым: 3 | Беттер: 108-115
СРАВНИТЕЛЬНЫЙ АНАЛИЗ ЭФФЕКТИВНОСТИ НЕЙРОПРОТЕКТОРОВ В КОМПЛЕКСНОЙ ТЕРАПИИ ИШЕМИЧЕСКИХ ИНСУЛЬТОВ
Инсульт был и остается одной из важных медико-социальных проблем современного общества. В настоящее время представления об этиологии, патогенетических механизмах и терапевтических подходах к рациональной терапии пациентов с инсультом претерпели кардинальные изменения. В статье подробно рассмотрена комбинированная фармакотерапия пациентов с инсультами, на основе результатов собственных клинических исследований проанализированы теоретические и практические аспекты нейропротективной терапии острых нарушений мозгового кровообращения. Продемонстрирована одинаковая эффективность применения различных...
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2019 жыл | Шығарылым: 3 | Беттер: 99-107
АНАЛИЗ СВЯЗЕЙ / ЗАВИСИМОСТЕЙ ОБЩЕГО СОСТОЯНИЯ ПРИ ПОСТУПЛЕНИИ И ИСХОДА ЗАБОЛЕВАНИЯ У БОЛЬНЫХ С ОПУХОЛЯМИ ГОЛОВНОГО МОЗГА
Введение. Опухоли головного мозга, несмотря на успехи в области диагностики и лечения новообразований в целом, являются актуальной проблемой в связи с низкой выживаемостью пациентов и высокой инвалидизацией.
Цель. Цель данного исследования: изучение связи/зависимости исхода хирургического лечения нейроонкологических больных от особенностей клинических проявлений заболевания и некоторых организационных аспектов.
Материал и методы. Исследование – обсервационное, описательно-аналитическое, проведено в 2017-2018 гг.
Методом сплошного наблюдения изучено 636 медицинских карт стац... Толығырақ
Цель. Цель данного исследования: изучение связи/зависимости исхода хирургического лечения нейроонкологических больных от особенностей клинических проявлений заболевания и некоторых организационных аспектов.
Материал и методы. Исследование – обсервационное, описательно-аналитическое, проведено в 2017-2018 гг.
Методом сплошного наблюдения изучено 636 медицинских карт стац... Толығырақ
2019 жыл | Шығарылым: 3 | Беттер: 92-98
DIAGNOSTIC CAPABILITIES OF DIFFUSE-WEIGHTED MAGNETIC RESONANCE IMAGING IMAGING IN BRAIN MENINGIOMAS
Relevance: The method of diffusion-weighted magnetic resonance imaging allows you to get information about the structural state of various tissues and organs. Currently, the method of diffuse-weighted images and the measured diffusion coefficient have not received widespread clinical use, with the exception of scientific works on the study of brain ischemia, demyelinating diseases, and injuries.
The aim of the work is to compare the values of the measured diffusion coefficient of various forms of meningiomas and assess the possibilities of applying the methods of diffusion-weighted magne... Толығырақ
The aim of the work is to compare the values of the measured diffusion coefficient of various forms of meningiomas and assess the possibilities of applying the methods of diffusion-weighted magne... Толығырақ
2019 жыл | Шығарылым: 3 | Беттер: 84-91
ПРОВЕДЕНИЕ ИНФОРМАЦИОННЫХ ИССЛЕДОВАНИЙ В МЕДИЦИНЕ: СОВЕТЫ ПО СТРАТЕГИЯМ И РЕСУРСАМ ОБЗОРА ЛИТЕРАТУРЫ
В настоящей работе представлен краткий обзор законодательных рамок информационного исследования в медицине, а также проведен обзор основных ресурсов, как библиографических баз данных, так и других. Описаны различные стратегии информационного поиска, которые зависят от цели обзора (плана исследования информации и критериев включения). Настоящая статья посвящена основам процесса обзора в рамках научных исследований по медицине и оценки технологий здравоохранения.
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2019 жыл | Шығарылым: 3 | Беттер: 68-76
COMPARATIVE EVALUATION OF BLOOD COLLECTION TUBES AND EXTRACTION METHODS FOR CIRCULATING TUMOR DNA
2025 жыл | Шығарылым: 6 | Беттер: 7-13
INFLUENCE OF SEX HORMONE-BINDING GLOBULIN (SHBG) ON THE LEVEL OF FREE TESTOSTERONE FRACTION IN OLDER OVERWEIGHT MEN
2025 жыл | Шығарылым: 6 | Беттер: 14-20
GENETIC VARIANTS IN LIPID-ASSOCIATED GENES IN THE KAZAKHSTANI COHORT WITH ATHEROSCLEROSIS AND HYPERTRIGLYCERIDEMIA
2025 жыл | Шығарылым: 5 | Беттер: 7-15
CLONAL HEMATOPOIESIS WITH INDETERMINATE POTENTIAL IN TET2 AND DNMT3A AMONG KAZAKHSTANI INDIVIDUALS WITH ATHEROSCLEROTIC DISEASE
2025 жыл | Шығарылым: 5 | Беттер: 16-23
RNA SEQUENCING OF SQUAMOUS ESOPHAGEAL CANCER: FROM THE COLLECTION OF THE BIOMATERIAL UNTIL SEQUENCING ON HISEQ2000
The squamous esophageal cancer is a disease which is highly frequent in Kazakhstan, the frequency of the disease is 10,1:100 000. In the mortality structure esophageal cancer takes place among men the 5th place, among women the 9th place in the Republic of Kazakhstan. The molecular mechanisms which contribute to the initiation and progression of the cancer pathology are not investigated enough. Nevertheless, the lack of the sensitive and specific biomarkers for the diagnosis of the cancer diseases, underlines about the necessity of the additional research works to study about the development o...
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2016 жыл | Шығарылым: 5 | Беттер: 53-63
DEVELOPMENT OF HALOPLEX PANEL AND PREPARATION OF DNA LIBRARIES FOR TARGETED SEQUENCING OF CARDIAC ARRHYTHMIAS
Method of preparation of custom HaloPlex cardiogenetic panel (Agilent Technologies) and method of preparation of DNA libraries for targeted sequencing of 96 genes associated with cardiac arrhythmias were described in details in this article. SureDesign Online Design software (Agilent Technologies) was used to create the HaloPlex panel. Final design was developed for Illumina platform using Human Genome version 19, GRCh 37. 19958 amplicons were generated by the program, 99,46% of all target regions were covered successfully. DNA libraries were prepared for 48 samples using t...
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2016 жыл | Шығарылым: 5 | Беттер: 43-52
DETERMINATION OF GENETIC VARIANTS ASSOCIATED WITH HYPERTENSION, OBESITY AND DIABETES IN KAZAKH POPULATION TO STUDY INTERACTION OF GENETIC VARIANTS AND METABOLOME
In this work genetic variants associated with hypertension, obesity and diabetes were characterized, and genomic data of 60 samples were compared using Т-HOD (The Text-mined Hypertension, Obesity and Diabetes candidate gene database (T-HOD) international database.
Genetic variants extracted from whole genomes and exomes, and associated with hypertension, obesity and diabetes based on PolyPhen2 and SIFT algorithmic predictors of mutation pathogenicity were analyzed. Seven genetic variants were detected in GHRL (rs4684677), MTHFR (rs1801133), OPRM1 (rs17999... Толығырақ
Genetic variants extracted from whole genomes and exomes, and associated with hypertension, obesity and diabetes based on PolyPhen2 and SIFT algorithmic predictors of mutation pathogenicity were analyzed. Seven genetic variants were detected in GHRL (rs4684677), MTHFR (rs1801133), OPRM1 (rs17999... Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 30-42
REPORT ABOUT THE CONFERENCE: THE INTERNATIONAL WОRLD HEALTH ORGANIZATION CONSULTATION ON NUTRITION AND PREGNANCY (27-28 June 2016, RIGA, LATVIA)
27-28 June 2016, Riga, Latvia hosted the International WHO consultation on nutrition and pregnancy, with participation of experts in the field of maternal and child health and the WHO Collaborating Centers from Poland, Latvia, Lithuania, Estonia, Italy, the UK, Kazakhstan, Tajikistan, Uzbekistan, Kyrgyzstan, Georgia, Armenia and Moldova. The key problems of women's health and nutrition, according to speakers from different countries are the following: the growth of overweight and obesity among women, excessive weight gain during pregnancy, low rates of exclusive breastfeeding in the first ...
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2016 жыл | Шығарылым: 4 | Беттер: 166-172
MODERN LAVAGE OF THE GASTROINTESTINAL TRACT FROM THE PERSPECTIVE OF THE QUALITY OF DIAGNOSIS AND TREATMENT IN ENDOSCOPIC, BARIATRIC SURGERY (LITERATURE REVIEW)
Introduction. The issue of quality lavage for the gastrointestinal tract before an abdominal surgery and endoscopic examination is of paramount significance, especially in patients with visceral obesity.
The aim of the study is to study historical aspects of intestinal cleansing, identify optimal ways to lavage and define its tolerability by patients.
Research methods. The review examines the effectiveness of different lavage techniques and patients’ preparation before surgeries and endoscopic examinations. The analysis of 77 sources relevant to the results of the study is also inc... Толығырақ
The aim of the study is to study historical aspects of intestinal cleansing, identify optimal ways to lavage and define its tolerability by patients.
Research methods. The review examines the effectiveness of different lavage techniques and patients’ preparation before surgeries and endoscopic examinations. The analysis of 77 sources relevant to the results of the study is also inc... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 145-165