ФОРМИРОВАНИЕ ОЧАГОВ Р53 СВЯЗАННОГО БЕЛКА 1 В ОПУХОЛЯХ ЩИТОВИДНОЙ ЖЕЛЕЗЫ: АКТИВАЦИЯ ГЕНЕТИЧЕСКОЙ НЕСТАБИЛЬНОСТИ В ТЕЧЕНИИ КАНЦЕРОГЕНЕЗА ЩИТОВИДНОЙ ЖЕЛЕЗЫ. ОБЗОР ЛИТЕРАТУРЫ
Введение: К настоящему времени достигнуты большие успехи в изучении молекулярно–клеточных механизмов канцерогенеза, установлении роли онкогенов и антионкогенов в развитии опухолей различной локализации, в том числе и РЩЖ. Подавляющее число доброкачественных и злокачественных опухолей щитовидной железы развивается из фолликулярного эпителия, которые имеют разную степень дифференцировки, разные морфогенетические и биохимические особенности, клиническое течение и прогноз.
Цель: проведение поиска научной информации по активации генетической нестабильности в течений канцерогенеза щитовидной ... Толығырақ
Цель: проведение поиска научной информации по активации генетической нестабильности в течений канцерогенеза щитовидной ... Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 25-37
ОРГАНИЗАЦИОННЫЕ ОСНОВЫ СКРИНИНГА КОЛОРЕКТАЛЬНОГО РАКА В МИРОВОЙ МЕДИЦИНСКОЙ ПРАКТИКЕ. ОБЗОР ЛИТЕРАТУРЫ
Актуальность. Рак ободочной и прямой кишки (колоректальный) является третьим по распространенности раком в мире. Он поддается скринингу, так как скрининговое исследование может быть осуществлено на предраковых, латентных, ранних и излечимых стадиях. При скрининге колоректального рака могут использоваться прямые или непрямые методы, применяемые произвольно или в структуре организованных программ. Большинство случаев колоректального рака диагностируется в возрасте старше 60 лет. Большинство программ скрининга относятся к лицам в возрасте 50-75 лет.
Цель обзора – Анализ подходов и р... Толығырақ
Цель обзора – Анализ подходов и р... Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 13-24
MODERN TENDENCY IN TREATMENT OF PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY. LITERARY REVIEW
Relevance: Carrying out of intensive therapy at severe traumatic brain injury is a complex of measures aimed on saving of the brain tissues and maintaining its functions. To achieve this goal, it is necessary to do timely diagnostics and monitoring of critical parameters - intracranial pressure and cerebral perfusion pressure; pathogenetically based therapy and nutritional support for critically ill patients.
Aim: The goal of this review was to find evidences of admissibility of use for such methods as control of cerebral perfusion pressure and intracranial pressure, anti-edematous thera... Толығырақ
Aim: The goal of this review was to find evidences of admissibility of use for such methods as control of cerebral perfusion pressure and intracranial pressure, anti-edematous thera... Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 5-12
ЛЕЧЕНИЕ ПОПЕРЕЧНОГО ПЛОСКОСТОПИЯ С HALLUX VALGUS ПРИ I и II ТИПЕ РАСПЛАСТАННОСТИ СТОПЫ
Введение. Статическая деформация переднего отдела стопы составляет до 80% среди ортопедической патологии стопы у взрослых. Патология вызывает значительное нарушение биомеханики всей нижней конечности, сопровождаясь болью в переднем отделе стопы, затруднение в подборе и ношении обуви, значительно снижает трудоспособность и качество жизни пациента. В связи с этим разработка технологии лечения статической деформации переднего отдела стопы, предусматривающей устранение Halluxvalgus, metatarsusprimavarus и плантарную девиацию центральных лучей стопы остается не полностью решенной и актуальной п...
Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 80-90
АНТИБИОТИКОРЕЗИСТЕНТНОСТЬ ШИГЕЛЛ НА СОВРЕМЕННОМ ЭТАПЕ
Введение. Одна из больших проблем практического здравоохранения на современном этапе – это рост антибиотикорезистентности шигелл к тем антибактериальным препаратам, которые широко сегодня используются в их лечении.
Цель исследования: изучить чувствительность штаммов Shigella spp., выделенных из кишечника больных острой дизентерией, к широко используемым в клинической практике антимикробным препаратам.
Материалы и методы. Проведен ретроспективный анализ 236 медицинских карт пациентов с диагнозом острой дизентерии, пролеченных на базе Городской инфекционной больница г. Астана за пе... Толығырақ
Цель исследования: изучить чувствительность штаммов Shigella spp., выделенных из кишечника больных острой дизентерией, к широко используемым в клинической практике антимикробным препаратам.
Материалы и методы. Проведен ретроспективный анализ 236 медицинских карт пациентов с диагнозом острой дизентерии, пролеченных на базе Городской инфекционной больница г. Астана за пе... Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 74-79
PRELIMINARY ANALYSIS OF THE HEALTH STATUS AND RADIATION DOSES OF RESIDENTS OF THE ABAY DISTRICT OF THE ABAY REGION, WHO ARE DESCENDANTS OF PERSONS EXPOSED TO RADIATION DUE TO NUCLEAR WEAPONS TESTS
2025 жыл | Шығарылым: 5 | Беттер: 32-39
TRENDS AND DISPARITIES IN CANCER MORBIDITY IN KAZAKHSTAN: A REGIONAL AND AGE-BASED ANALYSIS FOR 2014-2024
2025 жыл | Шығарылым: 5 | Беттер: 40-46
PATIENTS’ PERCEPTIONS OF THE QUALITY AND ACCESSIBILITY OF REHABILITATION SERVICES FOR LUNG CANCER: A CROSS-SECTIONAL STUDY
2025 жыл | Шығарылым: 5 | Беттер: 47-55
COMPARATIVE ANALYSIS OF COMPUTER TOMOGRAPHIC STAGING AND POSTOPERATIVE PATHOMORPHOLOGICAL STAGING IN STOMACH CANCER
2025 жыл | Шығарылым: 5 | Беттер: 56-62
INFLUENCE OF THE ECOSYSTEM ON HUMAN HEALTH IN THE INDUSTRIAL DEVELOPED REGIONS OF KAZAKHSTAN. A LITERATURE REVIEW
Introduction: In most regions of our republic, the environmental situation is not only unfavorable, but also catastrophic. Ecological problems of large cities of Kazakhstan are associated with the development of mining, non-ferrous and ferrous metallurgy. Excessively high concentration of the population, transport and industrial enterprises leads to a violation of the ecological balance of the natural environment. Air pollution is also one of the main causes of ecosystem damage, which adversely affects human health.
Purpose: to conduct a systematic search for scientific information on th... Толығырақ
Purpose: to conduct a systematic search for scientific information on th... Толығырақ
2018 жыл | Шығарылым: 4 | Беттер: 107-132
THE MODERN POSSIBILITIES OF PREDICTION OF PRE-ECLAMPSIA AND ITS COMPLICATIONS. A LITERATURE REVIEW
Background: One of the main causes of maternal and perinatal morbidity and mortality around the world is hypertensive disorder during pregnancy. After diagnosis of severe preeclampsia it is necessary of accurate risk assessment and management for both the mother and the fetus at different times. The prognostic model is an alternative basis for clinical practice, for predicting patient's future outcomes and for making decisions to improve them.
The aim: analysis of literature data of models for the prediction of pre-eclampsia and its complications.
Materials and metho... Толығырақ
The aim: analysis of literature data of models for the prediction of pre-eclampsia and its complications.
Materials and metho... Толығырақ
2018 жыл | Шығарылым: 4 | Беттер: 86-106
IMPROVEMENT OF METHODS OF TREATMENT OF GIPOSPADIA IN CHILDREN. STUDY PROTOCOL.
Introduction. Hypospodias refers to widespread anomalies of the genital organs. Treatment of hypospadias in children is performed only surgically. The variety of applied methods of treatment is caused by a large number of complications and the search for the optimal method of surgery for the correction of hypospadias.
The aim: to improve the results of treatment of anterior and middle hypospadias in children by introducing a modified urethroplasty method with a flap of the foreskin on the “feeding leg” and reducing postoperative complications.
Objectives:
1. ... Толығырақ
The aim: to improve the results of treatment of anterior and middle hypospadias in children by introducing a modified urethroplasty method with a flap of the foreskin on the “feeding leg” and reducing postoperative complications.
Objectives:
1. ... Толығырақ
2018 жыл | Шығарылым: 4 | Беттер: 73-85
CLINICAL RESULTS OF TREATMENT OF ANKLES FRACTURES WITH STOP RECOGNITION WITH USE OF THE APPARATUS FOR ACCURATE SPICE
Relevance: Ankle fractures are among the most common injuries of the lower limb. The greatest difficulties in their treatment are multi-ankles fractures with a dislocation of the foot. Transarticular spinal fixation attracts by the ease of holding, by the stability of the joint. However, the complications associated with the incorrect position of the locking spokes are likely. The device for exact carrying out of spokes promotes creation of conditions for stable fixation and reduction of frequency of complications.
The purpose of the study was to improve the technique of carrying the spo... Толығырақ
The purpose of the study was to improve the technique of carrying the spo... Толығырақ
2018 жыл | Шығарылым: 4 | Беттер: 61-72
OVERWEIGHT AND OBESITY AS A PREDISPOSITION FOR OSTEOPENIC CONDITION DEVELOPMENT IN A PATIENT WITH CORONARY ARTERY DISEASE
Relevance. Сalcification of arterial tissue is not just a passive process of calcium phosphate precipitation or adsorption in the terminal stage of arteriosclerosis, but also a highly organized process that is regulated by mechanisms analogous to bone mineralization.
Aim: to optimize the diagnosis of the structural and functional state of bone tissue in patients with coronary artery disease and obesity, and to determine the possible interrelationbetween these specifiedparameters and lipid metabolism indicators.
Materials and methods: A cohort prospective study conducted from 2016 t... Толығырақ
Aim: to optimize the diagnosis of the structural and functional state of bone tissue in patients with coronary artery disease and obesity, and to determine the possible interrelationbetween these specifiedparameters and lipid metabolism indicators.
Materials and methods: A cohort prospective study conducted from 2016 t... Толығырақ
2018 жыл | Шығарылым: 4 | Беттер: 50-60