МАТЕМАТИЧЕСКОЕ МОДЕЛИРОВАНИЕ БЛОКИРУЕМЫХ ШТИФТОВ МЕТОДОМ КОНЕЧНЫХ ЭЛЕМЕНТОВ
Внедрение
и использование новых типов ортопедических конструкций предполагает решение
сложных биомеханических, биофизических, технологических проблем. В настоящей
статье рассматривается математическая модель штифта, описанная с помощью метода конечных
элементов, и имитация явлений, происходящих в этой системе с течением времени.
Толығырақ
2017 жыл | Шығарылым: 6 | Беттер: 101-115
НОВЫЕ АСПЕКТЫ ЛЕЧЕНИЯ ХРОНИЧЕСКОЙ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ: ФОКУС НА АНТАГОНИСТЫ МИНЕРАЛОКОРТИКОИДНЫХ РЕЦЕПТОРОВ
В статье
представлены доказательства эффективности и безопасности применения блокаторов
рецепторов альдостерона, которые были получены в ходе выполнения нескольких
рандомизированных клинических испытаний. Представлен первый опыт применения
селективного антагониста минералокортикоидных рецепторов в клинической
практике.
Толығырақ
2017 жыл | Шығарылым: 6 | Беттер: 88-100
СРАВНИТЕЛЬНАЯ ОЦЕНКА КОСМЕТИЧЕСКИХ РЕЗУЛЬТАТОВ ЛЕЧЕНИЯ ПРИ СТАНДАРТНОМ, УСКОРЕННОМ ГИПОФРАКЦИОНИРОВАННОМ И ДИНАМИЧЕСКОМ РЕЖИМАХ ЛУЧЕВОЙ ТЕРАПИИ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ
На сегодняшний день оценка косметического результата представляет собой актуальную проблему и является одним из показателей хорошо проведенного органосберегающего лечения. Сохранение высокого уровня качества жизни, достижение хороших косметических результатов у больных ранним РМЖ после комплексного лечения является важной задачей современной онкологии.
2017 жыл | Шығарылым: 6 | Беттер: 78-87
АНАЛИЗ ОТДАЛЕННЫХ РЕЗУЛЬТАТОВ ЛЕЧЕНИЯ БОЛЬНЫХ РАКОМ МОЛОЧНОЙ ЖЕЛЕЗЫ В ЗАВИСИМОСТИ ОТ АДЪЮВАНТНЫХ РЕЖИМОВ ЛУЧЕВОЙ ТЕРАПИИ
2017 жыл | Шығарылым: 6 | Беттер: 67-77
АНАЛИЗ РАННИХ И ОТДАЛЕННЫХ РЕЗУЛЬТАТОВ ГИПОФРАКЦИОНИРОВАННОЙ ЛУЧЕВОЙ ТЕРАПИИ И ВНЕДРЕНИЕ ДАННОГО МЕТОДА В ПРОГРАММУ КОМПЛЕКСНОГО ЛЕЧЕНИЯ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ
Актуальность: Рак молочной железы (РМЖ) занимает первое место в структуре онкологической заболеваемости и смертности во всем мире. Диагностика РМЖ на ранних стадиях позволила изменить подход к лечению больных - замена проведения радикальных мастэктомий (РМЭ) органосохраняющими операциями (ОСО) с последующей лучевой терапией (ЛТ). Актуальна проблема новых методик послеоперационной ЛТ с гипофракционированными дозами облучения, которые при эквивалентном стандартному курсу воздействии на опухоль обладают меньшими рисками и сроками лечения. Одновременное развитие новых технологий ЛТ способст...
Толығырақ
2017 жыл | Шығарылым: 6 | Беттер: 53-66
EVALUATION OF THE SATISFACTION AND SUCCESS LEVELS OF BASIC LIFE SUPPORT, ADVANCED CARDIAC LIFE SUPPORT, AND TRAUMA TRAININGS PROVIDED TO SIXTH-YEAR STUDENTS OF MEDICAL FACULTY KARADENIZ TECHNICAL UNIVERSITY
2025 жыл | Шығарылым: 6 | Беттер: 54-66
GENETIC VARIANTS IN LIPID-ASSOCIATED GENES IN THE KAZAKHSTANI COHORT WITH ATHEROSCLEROSIS AND HYPERTRIGLYCERIDEMIA
2025 жыл | Шығарылым: 5 | Беттер: 7-15
CLONAL HEMATOPOIESIS WITH INDETERMINATE POTENTIAL IN TET2 AND DNMT3A AMONG KAZAKHSTANI INDIVIDUALS WITH ATHEROSCLEROTIC DISEASE
2025 жыл | Шығарылым: 5 | Беттер: 16-23
PRELIMINARY ANALYSIS AND ASSESSMENT OF THE HEALTH STATUS OF THE DESCENDANTS OF PERSONS EXPOSED TO RADIATION, LIVING IN THE BESKARAGAI DISTRICT OF THE ABAY REGION
2025 жыл | Шығарылым: 5 | Беттер: 24-31
COMPARATIVE EVALUATION OF PAIN SYNDROME OF OPERATED PATIENTS WITH INGUINAL HERNIAS
A comparative evaluation of operated patients with inguinal hernia in Medical Center Semey State Medical University fr om 2008 to 2015 year was performed. Patients of the main group were operated by our developed the method. The proposed method has advantages over traditional methods of plastics, is a universal intervention for large inguinal-scrotal and recurrent inguinal hernias. The technique allows to strengthen simultaneously the anterior and posterior wall of the inguinal canal, the inguinal ligament and the femoral canal, which leads to less pain in the postoperative period and the abse...
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 93-102
EFFECT OF EXTRACT ON ACTIVITY OF ENERGY METABOLISM ENZYMES AFTER COMBINED EFFECT OF EMOTIONAL STRESS AND SUBLETHAL DOSE OF γ-RADIATION IN REMOTE PERIOD
Introduction. During adaptation process complex changes occur in metabolic pathways; functional and structural changes occur in organs and tissue. Despite the great interest of researchers to this problem, the pathogenetic mechanisms of influence of stress, especially combined effect of stressors on the metabolic processes hasn’t been studied enough. Main criterion for the stability of the adaptive behavior of the organism is to maintain energy potential of biosystems constant. Given the importance of this system, it is necessary to define its role in formation of pathological process in anima...
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 67-78
THE FREQUENCY OF POLYMORPHISMS OF THE GENE 5382insC BRCA1 IN PATIENTS WITH FAMILIAL BREAST CANCERS ARE EXPOSED TO IONIZING RADIATION AS A RESULT OF SEMIPALATINSK NUCLEAR TEST SITE AND THEIR DESCENDANTS
Genetic changes play an important role among the risk factors for breast cancer, but their mechanisms of and contribution to the development of the disease is not finalized.
Purpose of the study: determining the frequency of the BRCA1 gene polymorphism 5382insC in patients with familial breast cancers in the region radiological trouble Semipalatinsk nuclear test site in the first and second generations of irradiated.
Materials and methods: The study included 250 women aged 40 to 79 years, Kazakh nationality, including 190 breast cancer patients, distributed in groups. The first gro... Толығырақ
Purpose of the study: determining the frequency of the BRCA1 gene polymorphism 5382insC in patients with familial breast cancers in the region radiological trouble Semipalatinsk nuclear test site in the first and second generations of irradiated.
Materials and methods: The study included 250 women aged 40 to 79 years, Kazakh nationality, including 190 breast cancer patients, distributed in groups. The first gro... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 58-66
FACTORS, ASSOCIATED WITH ONE YEAR SURVIVAL AFTER STROKE IN KAZAKHSTAN: A COHORT STUDY
Introduction. Many unresolved question exist about the predictors of stroke outcome. The evidence on the determinants of stroke survival in Kazakhstan is very scarce, despite the high prevalence of the problem.
The aim: To study factors associated with one -year stroke survival in a population of Semey, Kazakhstan.
Methods. All cases of stroke were included in a cohort in Semey from 01.01.2014 to 31.12.15 (N = 937).Survival of patients with stroke was assessed using Kaplan-Mayer curves and log-rank tests. Independent associations of the studied factors with survival were s... Толығырақ
The aim: To study factors associated with one -year stroke survival in a population of Semey, Kazakhstan.
Methods. All cases of stroke were included in a cohort in Semey from 01.01.2014 to 31.12.15 (N = 937).Survival of patients with stroke was assessed using Kaplan-Mayer curves and log-rank tests. Independent associations of the studied factors with survival were s... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 46-57
POLYMORPHISM OF IL10 GENE AT -1082G/A POSITION IN PATIENTS WITH ERYSIPELAS
The aim of this study is reveal the association of polymorphism of IL10 gene (rs1800896) at 1082 GA position with the erysipelas in Kazakh population.
Materials and methods. The polymorphism of IL10 gene (rs1800896) was assessed in 206 patients with erysipelas and 422 control subjects. Of them 143 patients with primary erysipelas and 63 with recurrence erysipelas. Genomic DNA was extracted from blood for genotyping. Genotyping of polymorphism of IL10 gene (-1082 GA) was conducted by method of polymerase chain reaction in real time. Pearson’s Chi tests ... Толығырақ
Materials and methods. The polymorphism of IL10 gene (rs1800896) was assessed in 206 patients with erysipelas and 422 control subjects. Of them 143 patients with primary erysipelas and 63 with recurrence erysipelas. Genomic DNA was extracted from blood for genotyping. Genotyping of polymorphism of IL10 gene (-1082 GA) was conducted by method of polymerase chain reaction in real time. Pearson’s Chi tests ... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 34-45