Проанализированы генетические варианты, выделенные из полных геномов и экзомов и показавшие ассоциацию с развитием гипертонии, ожирением и диабетом по обоим алгоритмическим предикторам патогенности мутаций PolyPhen2 и SIFT. Обнаружено семь генетических вариантов GHRL (rs4684677), MTHFR &... Толығырақ
Целью обзора было изучение исторических аспектов проблемы очищения кишечника, выбора оптимальных способов лаважа и переносимости его пациентами.
Методы исследования. В данном обзоре рассмотрена эффективность различных методов лаважа, подготовки больного перед эндоскопическим исследованием и операцией. Проведён анализ 77 литературных источников с результатами изучения данной проблемы.
Результаты. Си... Толығырақ
В последние годы активно изучается возможность применения витаминов группы В при сосудистых и ней родегенеративных заболеваниях. Дефицит витаминов В6, В12, В9, возникший в результате особенностей диеты и нарушения абсорбции, признан одним из основных факторов развития гипергомоцистеинемии. Установлено, что применение препа... Толығырақ
Introduction. The standard treatment for patients with inoperable locally advanced head and neck cancer is chemoradiotherapy with cisplatin. The high toxicity of this method doesn’t allow it to be used with 30,0 % of patients, namely patients older than 70 years, with low somatic status. One of the ways to increase the efficiency and reduce toxicity is the use of chemomodifiers in the chronomodulated mode in combination with non-standard dose fractionation regimes.
The aim of the study. To analyze the effectiveness of different methods...
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Іntrоductіоn. Іtʹs knоwn that реrsоns еxроsеd tо β− and γ–raуs, tоgеthеr wіth a dіffеrеnt оf damagіng еffеcts, рartіcular іmроrtancе іs alsо attachеd tо thе dіgеstіvе sуstеm. Thе dоmіnant rоlе оf nеutrоn−actіvatеd radіоnuclіdе Manganеsе−56 (56Mn) was nоtеd іn thе trеatіsеs оf scіеntіsts whо studіеd thе atomіc bоmb еffеcts оf Japanеsе cіtіеs, dеsеrvіng thе іntеrеst tоdaу.
Thе rеsеarch рurроsе. Іnvеstіgatе and comparе thе morphomеtrіc іndіcators іn thе small іntеstіnе оf rats еxроsеd tо low dosе bу β– and γ–raуs.
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ТолығырақThe role of the private sector in health care are still a subject of many debates, especially in the context of universal coverage of health services and the quality of care. Nowadays the relevance of this issue is justified by the difficulties facing the public sector in relation to health financing, health management and health services, as many governments experience financial constraints that force priorities and limit public spending. Advanced countries are in search of effective policies to improve hospital management and more efficient use of resources in the health sector. Expan...
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According to WHO, the incidence of newborns with intrauterine growth retardation ranges from 31.1% in Central Asia to 6, %% in Europe, from 2.4% to 17% in the CIS. The analysis of literary sources confirms the fact that the main socio-economic factors affecting the development of this pathology are smoking of mother, the level of ecology, the effect of industrial wastes and the problems of their utilization. The growth of general and somatic morbidity by separate classes of diseases was observed in almost 1.5-2.3 times, an increase in the frequency of complicated births, an i...
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