Online ISSN: 3007-0244,
Print ISSN:  2410-4280
Фильтр
Автор(ы):
  
ФАКТОРЫ, ВЛИЯЮЩИЕ НА ОДНОЛЕТНЮЮ ВЫЖИВАЕМОСТЬ ПАЦИЕНТОВ ПОСЛЕ ИНСУЛЬТА В КАЗАХСТАНЕ: КОГОРТНОЕ ИССЛЕДОВАНИЕ
Введение. Существует много нерешенных вопросов относительно предикторов исхода мозгового инсульта (МИ). В литературе имеется единичные публикации по детерминантам исхода МИ в Казахстане, несмотря на высокую распространенность проблемы.
Целью настоящего исследования являлось оценка влияния факторов риска на выживаемость больных с инсультом в течение года в популяции г. Семей.
Методы. В когортное исследование были включены все случаи МИ в г. Семей с 01.01.2014г. до 31.12.15г. (n=937). Выживаемость больных с МИ оценивалась с помощью метода Kaплана-Mайера с определение...
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 46-57

ПОЛИМОРФИЗМ ГЕНА ИЛ10 В ПОЛОЖЕНИИ -1082G/A У БОЛЬНЫХ РОЖЕЙ
Целью данного исследования является выявление связи полиморфизма гена ИЛ10-1082 GA (rs1800896) с заболеванием рожей у лиц казахской национальности.
Материалы и методы: Полиморфизм гена ИЛ10-1082 GA изучен у 206 больных рожей и 422 лиц контрольной группы. Из них у 143 больных первичной рожей и 63 больных рецидиврующей рожей. Для генотипирования были выделены геномная ДНК из крови. Генотипирование проводили методом полимеразной цепной реакции в режиме реал-тайм. Для статистической обработки использовались критерий χ2Пирсона и отношение шансов (ОШ) с 95% доверительными ...
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 34-45

ИЗМЕНЕНИЯ В ПЛАЗМЕ ТРИЙОДТИРОНИНА, ТИРОКСИНА И ТИРЕОТРОПНОГО ГОРМОНА ПОСЛЕ ОБЛУЧЕНИЯ 131 I У НОВОРОЖДЕННЫХ КРЫС, СОДЕРЖАВШИХСЯ НА ЙОДОДЕФИЦИТНОМ ПИТАНИИ
Background: Human thyroid gland is generally regarded as a relatively low-risk organ in terms of developing radiation-induced tumorigenesis. However, a rapid increase in the incidents of thyroid cancer after the Chernobyl nuclear reactor accident in 1986 provided additional insight into the risk of thyroid cancer. Three key risk factors have been identified to be involved in this increase: (1) internal irradiation from 131I fallout, (2) young age, and (3) a low-iodine diet. Our previous study demonstrated that the thyroid radiation dose was highest in the newborn rats f...
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 26-33

СРАВНЕНИЕ КОЛИЧЕСТВЕННЫХ ДАННЫХ ДВУХ ПАРНЫХ ВЫБОРОК С ИСПОЛЬЗОВАНИЕМ ПРОГРАММНОГО ОБЕСПЕЧЕНИЯ STATISTICA И SPSS: ПАРАМЕТРИЧЕСКИЕ И НЕПАРАМЕТРИЧЕСКИЕ КРИТЕРИИ
В настоящей работе представлены общие сведения об использовании парного критерия Стьюдента, непараметрического критерия Вилкоксона и критерия знаков для сравнения количественных признаков парных выборок. Описан алгоритм расчета данных критериев с использованием программного обеспечения Statistica 10 и SPSS 20 и представлена интерпретация результатов расчетов. Настоящая статья призвана дать общие сведения об использовании парного критерия Стьюдента, парного критерия Вилкоксона и критерия знаков, и не заменяет прочтения специализированной литературы по статистике и клинической эпидемиологии.
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 5-25

ADMINISTRATIVE BARRIERS OF THE IMPLEMENTATION OF SCREENING PROGRAMS FOR THE EARLY DETECTION OF ONCOLOGICAL DISEASES
Introduction. Within the framework of the State Programme for the Development of the Healthcare System of the Republic of Kazakhstan “Densaulyk” for 2016 – 2019, it is provided further development of key screening programs for the early detection of diseases with the greatest burden on public health, as well as the continuous improvement of the standards for monitoring programs and evaluating the effectiveness of screening programs. Purpose. Identify the barriers to the successful implementation of screening programs based on the results of economic evaluation in Pavlodar region. Materials a...
Толығырақ
2018 жыл | Шығарылым: 5 | Беттер: 57-67

MODERN STATUS OF INFECTIOUS INFRASTRUCTURE SECURITY OF THE DONOR BLOOD. LITERATURE REVIEW
Introduction: Ensuring sufficient stocks of safe blood should be an integral part of national health policy and infrastructure in each country. The national blood supply system should be based on national policy and legislative framework, on the application of standards and consistency in the field of quality assurance and safety of blood and its components. Purpose: Analysis of literature data on the features of development of blood service in developed countries of the world and Central Asia. Search strategy: The problem of donation and the safety of donor blood and its components is one o...
Толығырақ
2018 жыл | Шығарылым: 5 | Беттер: 42-56

DIAGNOSTICS OF ORTHOPEDIC PATHOLOGY OF PATELLOFEMORAL JOINT. LITERATURE REVIEW
Background. Pathology of the patellofemoral joint (PFJ) is a common, but insufficiently understood problem. According to some authors, about 15% of first-time patients have an isolated patellofemoral pathology. In another 25% of patients, patellofemoral symptoms are a secondary manifestation of other diseases, such as instability of the anterior cruciate ligament and rupture of the meniscus. In the diagnosis of pathology PFJ important carefully collected history and a full clinical examination.
The purpose of this review is to summarize the data on the diagnosis of orthopedic pathology of...
Толығырақ
2018 жыл | Шығарылым: 5 | Беттер: 31-41

TRIAGE SYSTEM: LITERATURE REVIEW, PROBLEMS AND SOLUTIONS IN KAZAKHSTAN
Introduction: The indicator of the state of health of the country's population directly depends on the quality of emergency care. At present, the first steps are being taken in implementation the triage system in the emergency rooms in Kazakhstan, therefore a new specialty of a "emergency doctor" has been introduced. Purpose: analysis of the triage systems in different countries with a view to inducing the interest of the medical community in Kazakhstan to use formal sorting systems in emergency departments. Methods: the search for relevant scientific publications was carried out in databas...
Толығырақ
2018 жыл | Шығарылым: 5 | Беттер: 23-30

THE ROLE OF SELENIUM IN CANCER PREVENTION
The aim of the present study was to analyze the scientific documentation about the effects of selenium (Se) in cancer prevention.
Methods. The search for relevant scientific publications was conducted in databases of evidence-based medicine (PubMed and Cochrane Library), specialized search systems (Google Scholar, Cyberleninka, and e-library). Inclusion criteria: studies performed in people published in English, Russian, as well as full versions of articles.
Results. In epidemiological studies conducted in 27 countries in Europe, the United States and Japan, it was found an inverse...
Толығырақ
2018 жыл | Шығарылым: 5 | Беттер: 16-22