ФАКТОРЫ, ВЛИЯЮЩИЕ НА ОДНОЛЕТНЮЮ ВЫЖИВАЕМОСТЬ ПАЦИЕНТОВ ПОСЛЕ ИНСУЛЬТА В КАЗАХСТАНЕ: КОГОРТНОЕ ИССЛЕДОВАНИЕ
Введение. Существует много нерешенных вопросов относительно предикторов исхода мозгового инсульта (МИ). В литературе имеется единичные публикации по детерминантам исхода МИ в Казахстане, несмотря на высокую распространенность проблемы.
Целью настоящего исследования являлось оценка влияния факторов риска на выживаемость больных с инсультом в течение года в популяции г. Семей.
Методы. В когортное исследование были включены все случаи МИ в г. Семей с 01.01.2014г. до 31.12.15г. (n=937). Выживаемость больных с МИ оценивалась с помощью метода Kaплана-Mайера с определение... Толығырақ
Целью настоящего исследования являлось оценка влияния факторов риска на выживаемость больных с инсультом в течение года в популяции г. Семей.
Методы. В когортное исследование были включены все случаи МИ в г. Семей с 01.01.2014г. до 31.12.15г. (n=937). Выживаемость больных с МИ оценивалась с помощью метода Kaплана-Mайера с определение... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 46-57
ПОЛИМОРФИЗМ ГЕНА ИЛ10 В ПОЛОЖЕНИИ -1082G/A У БОЛЬНЫХ РОЖЕЙ
Целью данного исследования является выявление связи полиморфизма гена ИЛ10-1082 GA (rs1800896) с заболеванием рожей у лиц казахской национальности.
Материалы и методы: Полиморфизм гена ИЛ10-1082 GA изучен у 206 больных рожей и 422 лиц контрольной группы. Из них у 143 больных первичной рожей и 63 больных рецидиврующей рожей. Для генотипирования были выделены геномная ДНК из крови. Генотипирование проводили методом полимеразной цепной реакции в режиме реал-тайм. Для статистической обработки использовались критерий χ2Пирсона и отношение шансов (ОШ) с 95% доверительными ... Толығырақ
Материалы и методы: Полиморфизм гена ИЛ10-1082 GA изучен у 206 больных рожей и 422 лиц контрольной группы. Из них у 143 больных первичной рожей и 63 больных рецидиврующей рожей. Для генотипирования были выделены геномная ДНК из крови. Генотипирование проводили методом полимеразной цепной реакции в режиме реал-тайм. Для статистической обработки использовались критерий χ2Пирсона и отношение шансов (ОШ) с 95% доверительными ... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 34-45
ИЗМЕНЕНИЯ В ПЛАЗМЕ ТРИЙОДТИРОНИНА, ТИРОКСИНА И ТИРЕОТРОПНОГО ГОРМОНА ПОСЛЕ ОБЛУЧЕНИЯ 131 I У НОВОРОЖДЕННЫХ КРЫС, СОДЕРЖАВШИХСЯ НА ЙОДОДЕФИЦИТНОМ ПИТАНИИ
Background: Human thyroid gland is generally regarded as a relatively low-risk organ in terms of developing radiation-induced tumorigenesis. However, a rapid increase in the incidents of thyroid cancer after the Chernobyl nuclear reactor accident in 1986 provided additional insight into the risk of thyroid cancer. Three key risk factors have been identified to be involved in this increase: (1) internal irradiation from 131I fallout, (2) young age, and (3) a low-iodine diet. Our previous study demonstrated that the thyroid radiation dose was highest in the newborn rats f...
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 26-33
СРАВНЕНИЕ КОЛИЧЕСТВЕННЫХ ДАННЫХ ДВУХ ПАРНЫХ ВЫБОРОК С ИСПОЛЬЗОВАНИЕМ ПРОГРАММНОГО ОБЕСПЕЧЕНИЯ STATISTICA И SPSS: ПАРАМЕТРИЧЕСКИЕ И НЕПАРАМЕТРИЧЕСКИЕ КРИТЕРИИ
В настоящей работе представлены общие сведения об использовании парного критерия Стьюдента, непараметрического критерия Вилкоксона и критерия знаков для сравнения количественных признаков парных выборок. Описан алгоритм расчета данных критериев с использованием программного обеспечения Statistica 10 и SPSS 20 и представлена интерпретация результатов расчетов. Настоящая статья призвана дать общие сведения об использовании парного критерия Стьюдента, парного критерия Вилкоксона и критерия знаков, и не заменяет прочтения специализированной литературы по статистике и клинической эпидемиологии.
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 5-25
СРАВНИТЕЛЬНЫЙ АНАЛИЗ РАСПРЕДЕЛЕНИЯ РАБОЧЕГО ВРЕМЕНИ У СОТРУДНИКОВ ОТДЕЛЕНИЙ ХИРУРГИЧЕСКОГО ПРОФИЛЯ ПРИ ИСПОЛЬЗОВАНИИ МЕДИЦИНСКОЙ ИНФОРМАЦИОННОЙ СИСТЕМЫ
2016 жыл | Шығарылым: 2 | Беттер: 150-161
CHEMOTHERAPY-INDUCED ECHOCARDIOGRAPHY CHANGES IN HEPATOCELLULAR CARCINOMA PATIENTS
2025 жыл | Шығарылым: 6 | Беттер: 47-53
EVALUATION OF THE SATISFACTION AND SUCCESS LEVELS OF BASIC LIFE SUPPORT, ADVANCED CARDIAC LIFE SUPPORT, AND TRAUMA TRAININGS PROVIDED TO SIXTH-YEAR STUDENTS OF MEDICAL FACULTY KARADENIZ TECHNICAL UNIVERSITY
2025 жыл | Шығарылым: 6 | Беттер: 54-66
THE EFFECT OF PRECONCEPTION CARE ON PERINATAL OUTCOMES OF THE MOTHER-PLACENTA-FETUS SYSTEM
2025 жыл | Шығарылым: 6 | Беттер: 67-76
MAGNETIC RESONANCE-GUIDED FOCUSED ULTRASOUND ABLATION IN THE MANAGEMENT OF SYMPTOMATIC ADENOMYOSIS: ASSESSMENT OF CLINICAL EFFICACY, SAFETY, AND IMPACT ON FERTILITY. A CASE SERIES
2025 жыл | Шығарылым: 6 | Беттер: 77-83
VALIDATION OF THE RUSSIAN AND KAZAKH VERSIONS OF THE PSQ-18: ADAPTED INSTRUMENT FOR PREGNANT WOMEN WITH GESTATIONAL DIABETES MELLITUS
2025 жыл | Шығарылым: 6 | Беттер: 84-90
HYPERHOMOCYSTEINEMIA AS A RISK FACTOR OF CARDIOVASCULAR DISEASES
Cardiovascular diseases are the leading cause of death. In this regard, the importance of the prevention problem increases, which is aimed at the identification and elimination of risk factors, which include elevated levels of homocysteine in the blood.
In recent years, actively studying the possibility of the use of B vitamins in vascular and neurodegenerative diseases. One of the main factors of hyperhomocysteinemia is the deficiency of vitamins B6, B12, B9 resulting from the features of the diet and impaired absorption. It was found that the use of preparations of B vitamins can reduc... Толығырақ
In recent years, actively studying the possibility of the use of B vitamins in vascular and neurodegenerative diseases. One of the main factors of hyperhomocysteinemia is the deficiency of vitamins B6, B12, B9 resulting from the features of the diet and impaired absorption. It was found that the use of preparations of B vitamins can reduc... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 129-144
MOLECULAR TYPE OF BREAST CANCER AS PROGNOSTIC FACTOR FOR METASTASIS
Introduction: The article provides an overview of the literature data on the peculiarities of metastasis of different subtypes of breast cancer (BC), which is characterized by heterogeneity, malignancy, early and rapid lymphatic and hematogenous metastasis. Modern studies have shown about the connection between the molecular type and localization of metastatic breast cancer.
Objective: Analysis of published data about the features of different molecular subtypes of breast cancer metastasis.
Materials and Methods: publications searched in the following databases: PubMed Med... Толығырақ
Objective: Analysis of published data about the features of different molecular subtypes of breast cancer metastasis.
Materials and Methods: publications searched in the following databases: PubMed Med... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 119-128
ASSOCIATION OF POLYMORPHISMS OF GENES OF IL1B (RS1143627), IL10 (RS1800896), IL17А (RS 2275913, RS8193036) WITH INFECTIOUS DISEASES INCLUDING ERYSIPELAS
The investigate of polymorphism of cytokine genes is an important in pathogenesis of many diseases and in identifying susceptibility to them. Knowledge of their role in the pathogenesis of many diseases, particularly infectious diseases are permits, on the one hand, to predict risk of disease or severity of its flow, on the other - to pick up individually specific therapy for a particular patient.
Despite the fact that to date, in the literature there are a significant number of studies that found an association between polymorphisms of cytokine genes and susceptibility to infectious dis... Толығырақ
Despite the fact that to date, in the literature there are a significant number of studies that found an association between polymorphisms of cytokine genes and susceptibility to infectious dis... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 104-118
STRUCTURE AND FREQUENCY OF CHILDBIRTH COMPLICATIONS OF MACROSOMIA
The relevance study macrosomia’s problem lies in the fact that the great mass of the fetus at birth is associated with increased frequency of obstetric pathology, which in turn leads to an increase in perinatal mortality and have a negative impact on the further development of children [11,12,13,14,15].
Research objectives: Determine the structure of childbirth complications and the frequency at macrosomia.
Materials and Methods: Study design: US -skrining. The study group included 147 birth stories with large fetus. Selection of cases in the control group held "random digits ... Толығырақ
Research objectives: Determine the structure of childbirth complications and the frequency at macrosomia.
Materials and Methods: Study design: US -skrining. The study group included 147 birth stories with large fetus. Selection of cases in the control group held "random digits ... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 93-103
DIAGNOSTIC VALUE OF MACROSOMIAS PREDICTOR
Determination of the expected weight of the fetus and the diagnosis of complications in childbirth remains debated issue. To select the optimum tactics of labor with large fetus and reduce the complications accurate methods of prenatal prediction of macrosomia are required.
Research objectives: to evaluate the diagnostic value of ultrasound measurement of abdominal circumference, as a predictor of macrosomia.
Materials and Methods: Study design: US -skrining. The study group included 147 birth stories with large fetus. Selection of cases in the control group held "random digit... Толығырақ
Research objectives: to evaluate the diagnostic value of ultrasound measurement of abdominal circumference, as a predictor of macrosomia.
Materials and Methods: Study design: US -skrining. The study group included 147 birth stories with large fetus. Selection of cases in the control group held "random digit... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 84-92