Online ISSN: 3007-0244,
Print ISSN:  2410-4280
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ОПИСАТЕЛЬНАЯ СТАТИСТИКА С ИСПОЛЬЗОВАНИЕМ ПАКЕТОВ СТАТИСТИЧЕСКИХ ПРОГРАММ STATISTICA И SPSS
В настоящей работе представлены основные методы предварительной статистической обработки данных с использованием программного обеспечения Statistica и SPSS для начинающих исследователей. Описаны различные типы данных, встречающихся в биомедицинских исследованиях, параметры нормального распределения количественных признаков, способы графического представления количественных результатов и методы проверки типа распределения. Настоящая статья призвана дать общие сведения об описательной статистике и проверке распределения данных, и не заменяет прочтения специализированной литературы по статистике ...
Толығырақ
2016 жыл | Шығарылым: 1 | Беттер: 7-23

ДЕФИЦИТ АЛЬФА-1 - АНТИТРИПСИНА И ХРОНИЧЕСКАЯ ОБСТРУКТИВНАЯ БОЛЕЗНЬ ЛЕГКИХ
Автор (лар): Жұмағалиева А. Н
Introduction. Alpha-1-antitrypsin deficiency (AATD) is a genetic disorder that manifests as pulmonary emphysema, liver cirrhosis and, rarely, as the skin disease panniculitis, and is characterized by low serum levels of AAT, the main protease inhibitor (PI) in human serum. The prevalence in Western Europe and in the USA is estimated at approximately 1 in 2,500 and 1 : 5,000 newborns, and is highly dependent on the Scandinavian descent within the population.
Chronic obstructive pulmonary disease (COPD) is one of the most essential causes of morbidity and mortality...
Толығырақ
2016 жыл | Шығарылым: 1 | Беттер: 127-136

УСОВЕРШЕНСТВОВАННЫЙ МЕТОД ОДНОСТОРОННЕЙ СПИНАЛЬНОЙ АНЕСТЕЗИИ, ПРЕДВАРИТЕЛЬНЫЕ РЕЗУЛЬТАТЫ
Введение. Односторонняя, или по-другому, монолатеральная спинальная анестезия (ОСА/МСА), это один из методов обезболивания при односторонних операциях на нижних конечностях. Однако данный вид обезболивания не лишен недостатков. Одним из главных критериев при оценке данного вида анестезии является частота удачных монолатеральных блокад, которая по данным разных авторов, варьирует от 13% до 94%. Такой разброс, несомненно, не является критерием «надежного» метода анестезии и во многих случаях объясняется техникой ее выполнения.  В последние годы, Мамыров Д.У. с соавторам...
Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 67-75

DANGEROUS AND UNDESIRABLE DRUG INTERACTIONS OF STATINS IN PATIENTS WITH CARDIOVASCULAR DISEASE
Relevance. Antihypercholesterolemic drugs fr om the group of statins have a significant impact on the metabolism of the human body. Consideration of pharmacokinetic features of statins and drug interaction with drugs of this group is an important aspect of their safe use. Drugs administered simultaneously with statins may be inducers or inhibitors (substrates) of CYP3A4/A5 cytochrome P450 liver isoenzymes, which should be considered in daily clinical practice in the management of this category of patients
The aim was to study the frequency and structure of the appointment of unw...
Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 55-66

PREVALENCE OF ATRIAL FIBRILLATION AND ITS CORRELATES IN HYPERTENSIVE PATIENTS WITHOUT CORONARY HEART DISEASE IN PRIMARY CARE SETTING
Hypertension is a risk factor for atrial fibrillation (AF). Primary prevention of AF in hypertension patients is the ultimate goal of the medical and public health community.
Aim: assess the prevalence and factors associated with AF in hypertensive patients without coronary heart disease (CHD) in primary care setting.
Methods: A cross–sectional study was conducted in January-September 2018. Hypertensive patients 40 years and above visiting primary care clinics during the study period were recruited (n=1121). Exclusion criteria were rheumatic and congenital h...
Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 44-54

RHEUMATOID ARTHRITIS AND FERTILITY: LITERATURE REVIEW
Introduction. Rheumatoid arthritis is a chronic inflammatory autoimmune disease that leads to disability, which occurs in women of predominantly childbearing age three times more often than men. Unfortunately, the issue of childbirth can be associated not only with the activity of the disease, but also with the availability of comprehensive medical care and knowledge of pharmacological treatment methods. Therefore, many women are struggling to find adequate information about planning pregnancy, childbirth and lactation.
Availability and advanced choice of pharmacotherapy can maintain the...
Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 38-43

FORMATION OF FOCI OF P53 BOUND PROTEIN 1 IN THYROID TUMORS: ACTIVATION OF GENETIC INSTABILITY DURING THYROID CARCINOGENESIS. LITERATURE REVIEW
Introduction: In our days big successes have been reached in studying of molecular–cellular mechanisms in carcinogenesis, establishing the role of oncogens and antioncogens in the development of tumors with various localization, including thyroid cancer. The vast majority of benign and malignant tumors of the thyroid gland develops from the follicular epithelium, which have different degrees of differentiation, different morphogenetic and biochemical features, clinical course and prognosis.
Objective: to conduct a search for scientific information on the activation of genetic instability...
Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 25-37