Online ISSN: 3007-0244,
Print ISSN:  2410-4280
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МЕТОДИКА ОПРЕДЕЛЕНИЯ ЛОКОМОТОРНОЙ АКТИВНОСТИ КРЫС
Введение: изучение локомоторной активности крыс широко применяется в экспериментальных научных исследованиях во всем мире. Это связано с тем, что оно считается неотъемлемой частью клинических испытаний. С помощью определения подвижности мы можем оценить воздействие определенного фармакологического препарата, влияние окружающей среды на психо-эмоциональное состояние живого организма. В статье представлены литературные данные о различных методиках определения локомоторной активности млекопитающих, а также наша личная разработка по изучению подвижности крыс.
Цель: разработать метод для кру...
Толығырақ
2016 жыл | Шығарылым: 6 | Беттер: 89-97

СОСТОЯНИЕ СЛИЗИСТОЙ ОБОЛОЧКИ ПОЛОСТИ РТА НА ЭТАПАХ ОРТОПЕДИЧЕСКОГО ЛЕЧЕНИЯ
Автор (лар): Ющенко П.Л
Введение. Качество ортопедического лечения зависит от скорости адаптации слизистой оболочки протезного ложа и пародонта к ортопедическим конструкциям.
Целью данного исследования является разработка способа обнаружения воспаления слизистой оболочки полости рта на этапах ортопедического лечения путем усовершенствования известного. Также необходима объективизация процесса выявления воспаления за счет графической визуализации полученных результатов и обеспечение повышения степени информативности исследования и эффективности ортопедического лечения на всех этапах подготовки полости рта к прот...
Толығырақ
2016 жыл | Шығарылым: 6 | Беттер: 62-72

COMPARATIVE ESTIMATION OF MORBIDITY RATE AND DEGREE OF SKIN LESIONS DURING HYPOFRACTIONATED AND TRADITIONAL RADIOTHERAPY OF BREAST CANCER
Background: Radiation therapy is a necessary step for the integrated treatment of breast cancer. The traditional scheme of treatment is the use of 2 Gray in 25 fractions to the total focal dose of 50 Gy. However, like any other treatment method, radiation therapy provides a variety of side effects on normal tissue in the irradiated field. To solve this problem it is necessary to develop suitable treatment regimens to achieve better local control with minimal risk on the normal tissues.
A variety of hypofractionated radiotherapy schedules has been proposed after surgery in the attempt to ...
Толығырақ
2016 жыл | Шығарылым: 6 | Беттер: 40-49

АНАЛИЗ НОМИНАЛЬНЫХ И РАНГОВЫХ ПЕРЕМЕННЫХ ДАННЫХ С ИСПОЛЬЗОВАНИЕМ ПРОГРАММНОГО ОБЕСПЕЧЕНИЯ STATISTICA И SPSS
В настоящей работе представлены общие сведения о выполнении статистического анализа данных, описываемых номинальными и ранговыми переменными, с использованием программного обеспечения Statistica 10 и SPSS 20. Рассматриваются критерии хи-квадрат Пирсона, поправка Йейтса, точный критерий Фишера, а также батарея статистических критериев для анализа ранговых переменных. Настоящая статья призвана дать общие сведения об анализе качественных данных, и не заменяет прочтения специализированной литературы по статистике и клинической эпидемиологии
Толығырақ
2016 жыл | Шығарылым: 6 | Беттер: 5-39

MOLECULAR TYPE OF BREAST CANCER AS PROGNOSTIC FACTOR FOR METASTASIS
Introduction: The article provides an overview of the literature data on the peculiarities of metastasis of different subtypes of breast cancer (BC), which is characterized by heterogeneity, malignancy, early and rapid lymphatic and hematogenous metastasis. Modern studies have shown about the connection between the molecular type and localization of metastatic breast cancer.
Objective: Analysis of published data about the features of different molecular subtypes of breast cancer metastasis.
Materials and Methods: publications searched in the following databases: PubMed Med...
Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 119-128

ASSOCIATION OF POLYMORPHISMS OF GENES OF IL1B (RS1143627), IL10 (RS1800896), IL17А (RS 2275913, RS8193036) WITH INFECTIOUS DISEASES INCLUDING ERYSIPELAS
The investigate of polymorphism of cytokine genes is an important in pathogenesis of many diseases and in identifying susceptibility to them. Knowledge of their role in the pathogenesis of many diseases, particularly infectious diseases are permits, on the one hand, to predict risk of disease or severity of its flow, on the other - to pick up individually specific therapy for a particular patient.
Despite the fact that to date, in the literature there are a significant number of studies that found an association between polymorphisms of cytokine genes and susceptibility to infectious dis...
Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 104-118

STRUCTURE AND FREQUENCY OF CHILDBIRTH COMPLICATIONS OF MACROSOMIA
The relevance study macrosomia’s problem lies in the fact that the great mass of the fetus at birth is associated with increased frequency of obstetric pathology, which in turn leads to an increase in perinatal mortality and have a negative impact on the further development of children [11,12,13,14,15].
Research objectives: Determine the structure of childbirth complications and the frequency at macrosomia.
Materials and Methods: Study design: US -skrining. The study group included 147 birth stories with large fetus. Selection of cases in the control group held "random digits ...
Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 93-103

DIAGNOSTIC VALUE OF MACROSOMIAS PREDICTOR
Determination of the expected weight of the fetus and the diagnosis of complications in childbirth remains debated issue. To select the optimum tactics of labor with large fetus and reduce the complications accurate methods of prenatal prediction of macrosomia are required.
Research objectives: to evaluate the diagnostic value of ultrasound measurement of abdominal circumference, as a predictor of macrosomia.
Materials and Methods: Study design: US -skrining. The study group included 147 birth stories with large fetus. Selection of cases in the control group held "random digit...
Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 84-92

Clinical and epidemiological characteristics of metastatic breast cancer in the north-eastern region of Kazakhstan
Actuality: Breast cancer (BC) is one of the most common diseases in the world among women. BC and its metastasis is a heterogeneous group of tumors that differ in morphology, clinical course, and sensitivity to the treatment, which is a serious clinical problem in oncology, thereby causing interest in this problem.
The aim of the study is to investigate the prevalence and clinical and morphological features of metastatic BC.
Materials and Methods: Design is retrospective study including 570 case histories. A retrospective analysis of data metastatic BC for the 2004-2013 yea...
Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 74-83