Online ISSN: 3007-0244,
Print ISSN:  2410-4280
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КОНЦЕПТУАЛЬНОЕ ВИДЕНИЕ РЕАЛИЗАЦИИ СТРАТЕГИИ МЕДИЦИНСКОЙ ПОМОЩИ, ОРИЕНТИРОВАННОЙ НА ПАЦИЕНТА В ОТЕЧЕСТВЕННОЙ И МИРОВОЙ ПРАКТИКЕ ЗДРАВООХРАНЕНИЯ
В статье представлен аналитический обзор основных подходов к организации медицинской помощи, ориентированной на пациента в отечественной и мировой практике здравоохранения. Анализ данных отечественной и зарубежной литературы позволяет заключить, что реализация пациент-ориентированной медицинской помощи обусловливает повышение эффективности медицинской помощи, способствует улучшению исходов заболевания и повышению уровня удовлетворенности пациентов оказываемой медицинской помощью.
Толығырақ
2014 жыл | Шығарылым: 5 | Беттер: 3-7

АНАЛИЗ И ОЦЕНКА НАРУШЕНИЙ ВЕГЕТАТИВНОЙ РЕГУЛЯЦИИ СРЕДИ ЛИЦ С СОМАТОФОРМНЫМИ РАССТРОЙСТВАМИ И ПРОЖИВАЮЩИХ НА ТЕРРИТОРИЯХ, ПРИЛЕГАЮЩИХ К СЕМИПАЛАТИНСКОМУ ЯДЕРНОМУ ПОЛИГОНУ
Проведен анализ нарушений вегетативной регуляции среди лиц с соматоформными расстройствами и прожива-ющих на территориях, прилегающих к Семипалатинскому ядерному. Полученные данные свидетельствовали о до-стоверном превышении симпатотонической регуляции кровообращения среди лиц основной группы, что свидетель-ствовало о несомненной связи нарушений вегетативной регуляции среди потомков, рожденных от облученных роди-телей с опосредованным радиационным воздействием.
Толығырақ
2014 жыл | Беттер: 16-19

REHABILITATION OF PATIENTS WITH CHRONIC LIVER DISEASES AND ITS EFFICIENCY MONITORING IN THE INCREASED RADIATION RISK REGION OF EAST KAZAKHSTAN AREA
The possibilities of noninvasive evaluation of the fibrosis formation were recognized by using discriminant score scale in comparison with the indicators of hepatic hemodynamics.
The antiproliferating properties of carnitine complex treatment among the East Kazakhstan residents exposed to radiation with chronic liver disease were identified.
Толығырақ
2014 жыл | Шығарылым: 2 | Беттер: 13-15

MICROSCOPIC PECULIARITIES OF DIFFERENT FORM OF GASTROESOPHAGEAL REFLUX DISEASE
The work devoted for investigation of the prevalence and significance of microscopic changes in the esophageal mucosa in gastroesophageal reflux disease (GERD) for the biopsy results. It was studied 223 patients with biopsy, which have been diagnosed with GERD. Material was divided after comparing endoscopic and histological data into three subgroups: non-erosive GERD was referred 104 cases or 46.64%; the picture of erosive ulcerous form corresponded in 77 patients, or 34.53%; Barrett's esophagus was detected in 42 patients (18.8%). The following histological fe...
Толығырақ
2014 жыл | Шығарылым: 2 | Беттер: 38-40

«КРИОТУР 600» АППАРАТЫНЫҢ КӨМЕГІМЕН ГЕМАНГИОМАНЫ ЕМДЕУ ТӘЖІРИБЕМІЗБЕН БӨЛІСУ
«Криотур 600» аппаратының қолданылуы ыңғайлы. Амбулаторлы тұрғыда жүзеге асатын болғандықтан экономикалық жағынан тиімді. Операцияға дейінгі арнайы дайындықты қажет етпейді. Температуралық режим реттелетін болғандықтан терең тері қабаттарының зақымдалуын сақтайды. Электор тоқ көзінен қуат алатын протативті аппарат болғандықтан қалаған орынға тасымалдауға болады.
Толығырақ
2014 жыл | Шығарылым: 1 | Беттер: 84-85

RNA SEQUENCING OF SQUAMOUS ESOPHAGEAL CANCER: FROM THE COLLECTION OF THE BIOMATERIAL UNTIL SEQUENCING ON HISEQ2000
The squamous esophageal cancer is a disease which is highly frequent in Kazakhstan, the frequency of the disease is 10,1:100 000. In the mortality structure esophageal cancer takes place among men the 5th place, among women the 9th place in the Republic of Kazakhstan. The molecular mechanisms which contribute to the initiation and progression of the cancer pathology are not investigated enough. Nevertheless, the lack of the sensitive and specific biomarkers for the diagnosis of the cancer diseases, underlines about the necessity of the additional research works to study about the development o...
Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 53-63

DEVELOPMENT OF HALOPLEX PANEL AND PREPARATION OF DNA LIBRARIES FOR TARGETED SEQUENCING OF CARDIAC ARRHYTHMIAS
Method of preparation of custom HaloPlex cardiogenetic panel (Agilent Technologies) and method of preparation of DNA libraries for targeted sequencing of 96 genes associated with cardiac arrhythmias were described in details in this article. SureDesign Online Design software (Agilent Technologies) was used to create the HaloPlex panel. Final design was developed for Illumina platform using Human Genome version 19, GRCh 37. 19958 amplicons were generated by the program, 99,46% of all target regions were covered successfully. DNA libraries were prepared for 48 samples using t...
Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 43-52

DETERMINATION OF GENETIC VARIANTS ASSOCIATED WITH HYPERTENSION, OBESITY AND DIABETES IN KAZAKH POPULATION TO STUDY INTERACTION OF GENETIC VARIANTS AND METABOLOME
In this work genetic variants associated with hypertension, obesity and diabetes were characterized, and genomic data of 60 samples were compared using Т-HOD (The Text-mined Hypertension, Obesity and Diabetes candidate gene database (T-HOD) international database.
Genetic variants extracted from whole genomes and exomes, and associated with hypertension, obesity and diabetes based on PolyPhen2 and SIFT algorithmic predictors of mutation pathogenicity were analyzed. Seven genetic variants were detected in GHRL (rs4684677), MTHFR (rs1801133), OPRM1 (rs17999...
Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 30-42

REPORT ABOUT THE CONFERENCE: THE INTERNATIONAL WОRLD HEALTH ORGANIZATION CONSULTATION ON NUTRITION AND PREGNANCY (27-28 June 2016, RIGA, LATVIA)
27-28 June 2016, Riga, Latvia hosted the International WHO consultation on nutrition and pregnancy, with participation of experts in the field of maternal and child health and the WHO Collaborating Centers from Poland, Latvia, Lithuania, Estonia, Italy, the UK, Kazakhstan, Tajikistan, Uzbekistan, Kyrgyzstan, Georgia, Armenia and Moldova. The key problems of women's health and nutrition, according to speakers from different countries are the following: the growth of overweight and obesity among women, excessive weight gain during pregnancy, low rates of exclusive breastfeeding in the first ...
Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 166-172

MODERN LAVAGE OF THE GASTROINTESTINAL TRACT FROM THE PERSPECTIVE OF THE QUALITY OF DIAGNOSIS AND TREATMENT IN ENDOSCOPIC, BARIATRIC SURGERY (LITERATURE REVIEW)
Introduction. The issue of quality lavage for the gastrointestinal tract before an abdominal surgery and endoscopic examination is of paramount significance, especially in patients with visceral obesity.
The aim of the study is to study historical aspects of intestinal cleansing, identify optimal ways to lavage and define its tolerability by patients.
Research methods. The review examines the effectiveness of different lavage techniques and patients’ preparation before surgeries and endoscopic examinations. The analysis of 77 sources relevant to the results of the study is also inc...
Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 145-165