ВЛИЯНИЕ ОТДАЛЕННЫХ ПОСЛЕДСТВИЙ ОСТРОГО ГАММА-ИЗЛУЧЕНИЯ И ЭМОЦИОНАЛЬНОГО СТРЕССА НА ФУНКЦИОНАЛЬНОЕ СОСТОЯНИЕ КОСТНОГО МОЗГА И ТИМУСА
В раннем периоде общего адаптационного синдрома снижается масса тимуса, повышается количество лимфо-идных клеток, в последующей стадии в тимусе возрастает масса и нормализуется число лимфоидных клеток. Во всех фазах адаптационного синдрома в костном мозге происходит повышение лимфоидных клеток.
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 62-65
ОТДАЛЕННЫЕ ЭФФЕКТЫ РАЗНОЙ ДОЗЫ ГАММА-ИЗЛУЧЕНИЯ НА ЛИМФОИДНЫЕ ОРГАНЫ ИММУНОГЕНЕЗА
В отдаленном периоде после сублетального и фракционированного действия гамма-излучения в тимусе и лим-фатических узлах тонкого кишечника снижены количества лимфоидных клеток. В тимусе и селезенке определяется атрофия, в лимфатических узлах тонкого кишечника - сниженный лимфоидный индекс и лимфоидных клеток.
В отдаленном периоде после воздействия малой дозы гамма-излучения отмечается атрофия тимуса и перерас-пределение лимфоидных клеток из тимуса и лимфатических узлов тонкого кишечника в костный мозг и селезенку.
Толығырақ
В отдаленном периоде после воздействия малой дозы гамма-излучения отмечается атрофия тимуса и перерас-пределение лимфоидных клеток из тимуса и лимфатических узлов тонкого кишечника в костный мозг и селезенку.
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 49-53
DENTAL STATUS OF PATIENTS DURING THE SUPPORTIVE CARE AT ANTINEOPLASTIC CHEMOTHERAPY FOR BREAST CANCER
Two groups were studied in a comparative aspect – 98 women with breast cancer during the courses of adjuvant chemo-therapy: the first was comprised of 26 patients who used their conventional means for oral hygiene; the second included 72 patients, who received the complex of therapeutic and preventive measures of supportive care. Dental toxicity was observed in 84.6-96.2 %, and has grown with the increase of the cycles of chemotherapy, reaching a maximum value on the V cycle of treatment. It is shown that the application of the developed complex significantly reduces the manifestations of ...
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 35-39
ДАННЫЕ СКРИНИНГА ПАТОЛОГИИ ЩИТОВИДНОЙ ЖЕЛЕЗЫ У ЖИТЕЛЕЙ РАЙОНОВ, ПОДВЕРГШИХСЯ РАДИАЦИОННОМУ ОБЛУЧЕНИЮ
В статье приведены данные, полученные в результате скрининга населения районов, подвергшихся радиационному облучению. Целью исследования было выявление частоты и особенностей патологии щитовидной железы у жителей районов Павлодарской и Восточно-Казахстанской областей, подвергшиеся радиационному облучению. Обследовано 1783 человека. Диффузный эутиреоидный зоб диагностирован в 32,97% случаев, колло-идно-узловой зоб у 13,60% обследованных, аутоиммуный тиреоидит у 52,96%, в 2,4% случаев наблюдался много-узловой зоб. Анализ функционального состояния щитовидной железы пока...
Толығырақ
2014 жыл | Шығарылым: 3 | Беттер: 22-25
МОДЕЛИРОВАНИЕ САХАРНОГО ДИАБЕТА 2 ТИПА ДЛЯ ИЗУЧЕНИЯ ЛЕКАРСТВЕННЫХ СРЕДСТВ С АНТИДИАБЕТИЧЕСКОЙ АКТИВНОСТЬЮ
Учитывая неуклонно возрастающее во всем мире число больных сахарным диабетом 2 типа, актуальной проблемой современной фармакологии продолжает оставаться разработка антидиабетических препаратов, обладающих высокой терапевтической активностью и имеющих более совершенный профиль безопасности. В связи с этим важное значение имеет моделирование сахарного диабета, позволяющее достоверно выявлять наличие той или иной фармакологической активности или новых деталей в механизме действия лекарственных средств. Модели сахарного диабета могут быть получены на различных видах животных ...
Толығырақ
2014 жыл | Шығарылым: 4 | Беттер: 4-8
COMPARATIVE EVALUATION OF BLOOD COLLECTION TUBES AND EXTRACTION METHODS FOR CIRCULATING TUMOR DNA
2025 жыл | Шығарылым: 6 | Беттер: 7-13
INFLUENCE OF SEX HORMONE-BINDING GLOBULIN (SHBG) ON THE LEVEL OF FREE TESTOSTERONE FRACTION IN OLDER OVERWEIGHT MEN
2025 жыл | Шығарылым: 6 | Беттер: 14-20
ASSESSMENT OF THE PROBABILITY OF DEVELOPING CARDIORENAL SYNDROME TYPE 2 DEPENDING ON POTENTIAL BIOMARKERS IN PEDIATRIC PATIENTS
2025 жыл | Шығарылым: 6 | Беттер: 21-29
MORPHO-GENETIC VARIABILITY IN MYOCARDIAL TISSUE AFTER SEPTAL MYECTOMY IN PATIENTS WITH OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY: A FOUR-CASE SERIES STUDY
2025 жыл | Шығарылым: 6 | Беттер: 30-37
CLINICAL EFFICACY OF SELECTIVE PLASMA FILTRATION (EVACLIO) IN CARDIOVASCULAR COMPLICATIONS: A CASE SERIES FROM THE HEART CENTER KAZAKHSTAN
2025 жыл | Шығарылым: 6 | Беттер: 38-46
FACTORS INFLUENCING ON ADHERENCE TO ANTIHYPERTENSIVE THERAPY AT PATIENTS WITH ARTERIAL HYPERTENSION IN EAST KAZAKHSTAN
Aim of research – to analyse influence of social-economical, clinical and pharmaco-epidemiological factors to patients’s compliance on the treatment in population of East Kazakhstan.
Materials and methods: Study design – cross-sectional study. The study included 2346 patients with arterial hypertension aged 25 to 80 years, including 1281 men (54,6%) and 1065 women (45,4%). The average age is 55,2 ± 1,1 years.
Carried out estimation of compliance to medical therapy at patients with arterial hypertension. Depending on the degree of compliance, estimated patien... Толығырақ
Materials and methods: Study design – cross-sectional study. The study included 2346 patients with arterial hypertension aged 25 to 80 years, including 1281 men (54,6%) and 1065 women (45,4%). The average age is 55,2 ± 1,1 years.
Carried out estimation of compliance to medical therapy at patients with arterial hypertension. Depending on the degree of compliance, estimated patien... Толығырақ
2017 жыл | Шығарылым: 5 | Беттер: 42-54
METHODOLOGICAL BASIS OF THE ORGANIZATION OF MEDICAL AND ENVIRONMENTAL RESEARCH TO ASSESS THE HEALTH STATUS OF THE POPULATION LIVING IN ECOLOGICALLY UNFAVORABLE TERRITORIES OF KAZAKHSTAN
Background. Problem of population health status and life span is the strategic task in Kazakhstan. The present time in the most industrial territories of Kazakhstan there is situation related with increasing of technogenic and anthropogenic risk factors influence to environment and rising of ecological load for the population. East-Kazakhstan, Pavlodar, Karaganda and Aktobe regions are such ecologically unfavorable areas.
Aim: description of the methodological and procedural framework for the implementation of the scientific program “Development of scientific and methodological bases fo... Толығырақ
Aim: description of the methodological and procedural framework for the implementation of the scientific program “Development of scientific and methodological bases fo... Толығырақ
2017 жыл | Шығарылым: 5 | Беттер: 29-41
SURVIVAL ANALYSIS IN HEALTH SCIENCES USING SPSS SOFTWARE
In this paper we present theoretical basis of the two methods of survival analysis for the prognosis of survival dependent on one or two independent variables during the time period with the use of SPSS software. We describe the main principles of Kaplan-Meier analysis and survival tables for one or several groups. Special emphasis is given to interpretation of the results and practical examples
Толығырақ
2017 жыл | Шығарылым: 5 | Беттер: 5-28
QUALITY OF LIFE OF PEOPLE BORN PREMATURELY: A SYSTEMATIC REVIEW
Background: One of the main priorities in the Republic of Kazakhstan is maternal and children health. Knowledge of the quality of life and the development of premature babies is an important component for achieving the goals in the area of maternal and child health.
Objective: To conduct a systematic analysis of studies on the quality of life of prematurely born people at various ages.
Methods: Search was created in Web of Science, PubMed, Medline, EBSCOhost databases, we also looked at the additional information resource Google Scholar. Repeated publications were e... Толығырақ
Objective: To conduct a systematic analysis of studies on the quality of life of prematurely born people at various ages.
Methods: Search was created in Web of Science, PubMed, Medline, EBSCOhost databases, we also looked at the additional information resource Google Scholar. Repeated publications were e... Толығырақ
2017 жыл | Шығарылым: 4 | Беттер: 113-123
CLINICAL AND EPIDEMIOLOGICAL SIGNIFICANCE SYNDROME OF CONNECTIVE TISSUE DYSPLASIA IN THE FORMATION OF CONGENITAL HEART DEFECTS. REVIEW.
Structure of all congenital malformations include 30% malformations of the heart and blood vessels (CHD - congenital heart disease), congenital malformations make a significant contribution for child mortality and disability, requiring significant economic costs for surgical correction and social assistance for children with disabilities. In the Republic of Kazakhstan, practical measurement of CHD among live births is 8-10 per 1,000 live births and every year the total number of live births children with CHD in Kazakhstan is 3,000.
The aim of study was analyzed of lite... Толығырақ
The aim of study was analyzed of lite... Толығырақ
2017 жыл | Шығарылым: 4 | Беттер: 94-112