МИОКАРД ИНФАРКТІМЕН БІРІККЕН ЦЕРЕБРОВАСКУЛЯРЛЫ ПАТОЛОГИЯСЫ БАР НАУҚАСТАРДАҒЫ HLA АНТИГЕНДЕРІНІҢ БӨЛІНУІ
Всего обследовано 25 больных с инфарктом миокарда сочетанной с цереброваскулярной патологией. Кон-трольную группу составили доноры здоровые лица 442 человек. Типирование антигенов гистосовместимости HLA I класса проводились в стандартном двухступенчатом микролимфоцитоксическом тесте. Иммуногенетическими маркерами повышенного риска заболеваемости инфаркта миокарда при сочетании цереброваскулярной патологией у казахов являются антигены HLA А1, А2, А9, В5, В7, В12, В35, В40 и гаплотипы А1/В12, А2/В12, А9/В12; у русских HLA А10, В5, В7, В17, В40; фенотип В7/В8 и гаплотипы А10/В5, А10/В7. Протектив...
Толығырақ
2012 жыл | Шығарылым: 3 | Беттер: 23-26
Влияние радиационных и нерадиационных факторов риска на формирование заболева-ний системы кровообращения и методы их профилактики с позиции доказательной меди-цины
В статье представлен литературный обзор по проблеме изучения радиационных и нерадиационных факторов риска болезней системы кровообращения. Проведен анализ информации из баз данных по доказательной медицине по профилактическим и реабилитационным мероприятиям, включающим длительный и постоянный мониторинг путем проведения скрининговых обследований на местах
Толығырақ
2012 жыл | Шығарылым: 3 | Беттер: 20-23
ДОНОЗОЛОГИЧЕСКАЯ ДИАГНОСТИКА И ПРОФИЛАКТИКА БОЛЕЗНЕЙ СИСТЕМЫ КРОВООБРАЩЕНИЯ У ЛИЦ, ПОДВЕРГАВШИХСЯ ВОЗДЕЙСТВИЮ РАДИАЦИОННОГО ФАКТОРА, НА ОСНОВЕ ИЗУЧЕНИЯ ГЕННОГО ПОЛИМОРФИЗМА
В статье представлены принципы донозологической диагностики социально значимых болезней системы кровообращения на основе определения полиморфизма генов-кандидатов, определяющих уровень артериального давления, обмен гомоцистеина и метаболизм липидов. Исследование позволило установить высокую корреляци-онную связь гетерозиготных нарушений в отношении гена-кандидата AGT, предполагающую высокую степень наследования сосудистой патологии экспонированных радиацией родителей их потомками. Результаты ис-следований свидетельствуют о необходимости совершенствования системы длительного монитори...
Толығырақ
2012 жыл | Шығарылым: 3 | Беттер: 18-20
К ПРОБЛЕМЕ ОРГАНИЗАЦИИ САМОСТОЯТЕЛЬНОЙ РАБОТЫ СТУДЕНТОВ
В статье рассматривается проблема организации самостоятельной работы студентов. Oриентация на СРС при хорошо организованном и научно обоснованном методическом обеспечении повышает качественные пока-затели образовательного процесса, дает совершенно новые возможности.
Толығырақ
2012 жыл | Шығарылым: 3 | Беттер: 15-17
ЛИТЕРАТУРНЫЙ ОБЗОР БАРЬЕРОВ ДОСТУПА МОЛОДЫХ ЛЮДЕЙ К МЕДИКО-СОЦИАЛЬНЫМ СЕРВИСАМ
2012 жыл | Шығарылым: 3 | Беттер: 14-15
COMBINATIONS OF CONGENITAL HEART DISEASES AND A CONNECTIVE TISSUE DYSPLASIA AMONG CHILDREN OF SEMEY
Introduction. There is evidence on common mechanisms of congenital heart diseases (CHD) and connective tissue dysplasia (CTD), which increases odds for their comorbidities. The latter may be associated with poorer prognosis for CHD. However, the associations between CHD and CTD in Kazakhstan have been poorly studied so far.
Aim – to assess the frequency of CTD signs in children with CHD living in Semey, Kazakhstan.
Materials and methods. We examined 168 children aged 1 to14 years, including 84 – with CHD and 80 children with no signs of CHD.
Associations betw... Толығырақ
Aim – to assess the frequency of CTD signs in children with CHD living in Semey, Kazakhstan.
Materials and methods. We examined 168 children aged 1 to14 years, including 84 – with CHD and 80 children with no signs of CHD.
Associations betw... Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 101-110
CAUSES OF REFUSING MEDICAL EXAMINATIONBY PATIENTS WITH SUSPECTED CANCER AS PERCEIVED BY PRIMARY CARE PHYSICIANS IN SOUTH KAZAKHSTAN REGION
Objective: To identify the most frequent causes of refusing thorough medical examinations by patients with suspected cancer as perceived by primary care physicians in South Kazakhstan Region (SKR).
Methods: We performed a cross-sectional study, which included 500 primary care physicians in SKR. Data collection took place between 01 January 2016 and 14 April 2016). The questionnaire contained 33 semi-open questions. Filling out time was between 20 and 25 minutes. Only doctors who worked at policlinics during the time of the study were included. Results are presented absolute n... Толығырақ
Methods: We performed a cross-sectional study, which included 500 primary care physicians in SKR. Data collection took place between 01 January 2016 and 14 April 2016). The questionnaire contained 33 semi-open questions. Filling out time was between 20 and 25 minutes. Only doctors who worked at policlinics during the time of the study were included. Results are presented absolute n... Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 90-100
IMPACT OF ERYTHROCYTES ANTIGENS ON DEVELOPMENT OF LIVER CIRRHOSIS
Introduction. High rates of prevalence and mortality of liver cirrhosis, it’s late clinical manifestation, disadvantages of liver biopsy highlight the background points of our research.
Aim. Research of erythrocytes’ antigens profile in patients with liver cirrhosis of Kazakh and Russian ethnical groups.
Materials and Methods: One hundred and forty patients with liver cirrhosis and 272 relatively healthy participants of both of nationalities were involved into research. АВ0, MNS, P1, CDE systems of erythrocytes of venous blood were investigated. For the comparison of the frequenc... Толығырақ
Aim. Research of erythrocytes’ antigens profile in patients with liver cirrhosis of Kazakh and Russian ethnical groups.
Materials and Methods: One hundred and forty patients with liver cirrhosis and 272 relatively healthy participants of both of nationalities were involved into research. АВ0, MNS, P1, CDE systems of erythrocytes of venous blood were investigated. For the comparison of the frequenc... Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 80-89
PSYCHOTHERAPEUTIC REHABILITATION AND NORMALIZATION OF PSYCHOEMOTIONAL AND FUNCTIONAL CONDITION OF PATIENTS WITH PAIN SYNDROMES IN BRAIN ORGANIC LESIONS
Background. Psychoemotional violations impede adequate recovery of neurological function in patients with pain syndromes on a background of central nervous system, enhance their social and domestic roles, as well as substantially reduce the quality of life in patients.
Aim: to increase the efficiency of the rehabilitation of patients with pain syndromes on a background of organic defeat CNS.
Methods. The study has a prospective, comparative open character. The results of psychological rehabilitation were analyzed in 500 patients with stroke, head injury and suffering pain syndromes... Толығырақ
Aim: to increase the efficiency of the rehabilitation of patients with pain syndromes on a background of organic defeat CNS.
Methods. The study has a prospective, comparative open character. The results of psychological rehabilitation were analyzed in 500 patients with stroke, head injury and suffering pain syndromes... Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 64-79
RNA SEQUENCING OF SQUAMOUS ESOPHAGEAL CANCER: FROM THE COLLECTION OF THE BIOMATERIAL UNTIL SEQUENCING ON HISEQ2000
The squamous esophageal cancer is a disease which is highly frequent in Kazakhstan, the frequency of the disease is 10,1:100 000. In the mortality structure esophageal cancer takes place among men the 5th place, among women the 9th place in the Republic of Kazakhstan. The molecular mechanisms which contribute to the initiation and progression of the cancer pathology are not investigated enough. Nevertheless, the lack of the sensitive and specific biomarkers for the diagnosis of the cancer diseases, underlines about the necessity of the additional research works to study about the development o...
Толығырақ
2016 жыл | Шығарылым: 5 | Беттер: 53-63