ФОРМИРОВАНИЕ ОЧАГОВ Р53 СВЯЗАННОГО БЕЛКА 1 В ОПУХОЛЯХ ЩИТОВИДНОЙ ЖЕЛЕЗЫ: АКТИВАЦИЯ ГЕНЕТИЧЕСКОЙ НЕСТАБИЛЬНОСТИ В ТЕЧЕНИИ КАНЦЕРОГЕНЕЗА ЩИТОВИДНОЙ ЖЕЛЕЗЫ. ОБЗОР ЛИТЕРАТУРЫ
Введение: К настоящему времени достигнуты большие успехи в изучении молекулярно–клеточных механизмов канцерогенеза, установлении роли онкогенов и антионкогенов в развитии опухолей различной локализации, в том числе и РЩЖ. Подавляющее число доброкачественных и злокачественных опухолей щитовидной железы развивается из фолликулярного эпителия, которые имеют разную степень дифференцировки, разные морфогенетические и биохимические особенности, клиническое течение и прогноз.
Цель: проведение поиска научной информации по активации генетической нестабильности в течений канцерогенеза щитовидной ... Толығырақ
Цель: проведение поиска научной информации по активации генетической нестабильности в течений канцерогенеза щитовидной ... Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 25-37
ОРГАНИЗАЦИОННЫЕ ОСНОВЫ СКРИНИНГА КОЛОРЕКТАЛЬНОГО РАКА В МИРОВОЙ МЕДИЦИНСКОЙ ПРАКТИКЕ. ОБЗОР ЛИТЕРАТУРЫ
Актуальность. Рак ободочной и прямой кишки (колоректальный) является третьим по распространенности раком в мире. Он поддается скринингу, так как скрининговое исследование может быть осуществлено на предраковых, латентных, ранних и излечимых стадиях. При скрининге колоректального рака могут использоваться прямые или непрямые методы, применяемые произвольно или в структуре организованных программ. Большинство случаев колоректального рака диагностируется в возрасте старше 60 лет. Большинство программ скрининга относятся к лицам в возрасте 50-75 лет.
Цель обзора – Анализ подходов и р... Толығырақ
Цель обзора – Анализ подходов и р... Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 13-24
MODERN TENDENCY IN TREATMENT OF PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY. LITERARY REVIEW
Relevance: Carrying out of intensive therapy at severe traumatic brain injury is a complex of measures aimed on saving of the brain tissues and maintaining its functions. To achieve this goal, it is necessary to do timely diagnostics and monitoring of critical parameters - intracranial pressure and cerebral perfusion pressure; pathogenetically based therapy and nutritional support for critically ill patients.
Aim: The goal of this review was to find evidences of admissibility of use for such methods as control of cerebral perfusion pressure and intracranial pressure, anti-edematous thera... Толығырақ
Aim: The goal of this review was to find evidences of admissibility of use for such methods as control of cerebral perfusion pressure and intracranial pressure, anti-edematous thera... Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 5-12
ЛЕЧЕНИЕ ПОПЕРЕЧНОГО ПЛОСКОСТОПИЯ С HALLUX VALGUS ПРИ I и II ТИПЕ РАСПЛАСТАННОСТИ СТОПЫ
Введение. Статическая деформация переднего отдела стопы составляет до 80% среди ортопедической патологии стопы у взрослых. Патология вызывает значительное нарушение биомеханики всей нижней конечности, сопровождаясь болью в переднем отделе стопы, затруднение в подборе и ношении обуви, значительно снижает трудоспособность и качество жизни пациента. В связи с этим разработка технологии лечения статической деформации переднего отдела стопы, предусматривающей устранение Halluxvalgus, metatarsusprimavarus и плантарную девиацию центральных лучей стопы остается не полностью решенной и актуальной п...
Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 80-90
АНТИБИОТИКОРЕЗИСТЕНТНОСТЬ ШИГЕЛЛ НА СОВРЕМЕННОМ ЭТАПЕ
Введение. Одна из больших проблем практического здравоохранения на современном этапе – это рост антибиотикорезистентности шигелл к тем антибактериальным препаратам, которые широко сегодня используются в их лечении.
Цель исследования: изучить чувствительность штаммов Shigella spp., выделенных из кишечника больных острой дизентерией, к широко используемым в клинической практике антимикробным препаратам.
Материалы и методы. Проведен ретроспективный анализ 236 медицинских карт пациентов с диагнозом острой дизентерии, пролеченных на базе Городской инфекционной больница г. Астана за пе... Толығырақ
Цель исследования: изучить чувствительность штаммов Shigella spp., выделенных из кишечника больных острой дизентерией, к широко используемым в клинической практике антимикробным препаратам.
Материалы и методы. Проведен ретроспективный анализ 236 медицинских карт пациентов с диагнозом острой дизентерии, пролеченных на базе Городской инфекционной больница г. Астана за пе... Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 74-79
COMPARATIVE EVALUATION OF BLOOD COLLECTION TUBES AND EXTRACTION METHODS FOR CIRCULATING TUMOR DNA
2025 жыл | Шығарылым: 6 | Беттер: 7-13
INFLUENCE OF SEX HORMONE-BINDING GLOBULIN (SHBG) ON THE LEVEL OF FREE TESTOSTERONE FRACTION IN OLDER OVERWEIGHT MEN
2025 жыл | Шығарылым: 6 | Беттер: 14-20
GENETIC VARIANTS IN LIPID-ASSOCIATED GENES IN THE KAZAKHSTANI COHORT WITH ATHEROSCLEROSIS AND HYPERTRIGLYCERIDEMIA
2025 жыл | Шығарылым: 5 | Беттер: 7-15
CLONAL HEMATOPOIESIS WITH INDETERMINATE POTENTIAL IN TET2 AND DNMT3A AMONG KAZAKHSTANI INDIVIDUALS WITH ATHEROSCLEROTIC DISEASE
2025 жыл | Шығарылым: 5 | Беттер: 16-23
ANALYSIS OF SENSITIVENESS OF YELLOW-GREEN STAPHYLOCOCCUS TO THE ANTIBIOTICS
Work is sanctified to the study and analysis of sensitiveness and stability of staphylococcus to different antibacterial preparations.
As an object for research the medical personnel of establishments of institution of the East-Kazakhstan criminal-actuator system Departament, at that a laboratory inspection was conducted on of pathogenic staphylococcus and biometrial from patients among the special contingent of attendance centres with the diseases of festering-inflammatory character.
Laboratory researches were conducted on the generally accepted methodology. Тhe antibiotikusensiti... Толығырақ
As an object for research the medical personnel of establishments of institution of the East-Kazakhstan criminal-actuator system Departament, at that a laboratory inspection was conducted on of pathogenic staphylococcus and biometrial from patients among the special contingent of attendance centres with the diseases of festering-inflammatory character.
Laboratory researches were conducted on the generally accepted methodology. Тhe antibiotikusensiti... Толығырақ
2014 жыл | Шығарылым: 2 | Беттер: 92-94
STUDY OF EFFECT OF SOME PLANTS ON CONDITION OF BACTERIA CARRYING OF AUROCOCCUS AMONG PUPILS
Inquiry results of group of pupils showed the presence of fixed number of bacteria carriers of aurococcus. Study of bacte-ricidal action of celandine and parmelia (just as in vitro so and in vivo) in separated strain of aurococcus confirmed these properties and comparison of findings showed the biggest efficiency of parmelia infusion.
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2014 жыл | Шығарылым: 2 | Беттер: 89-91
DETECTION OF TUBERCULOSIS AND CHRONIC NONSPECIFIC LUNG DISEASES IN ADULTS IN THE CITY OF SHYMKENT
The article analyzes the condition of tuberculosis`s detection and nonspecific lung diseases in adults in the city of Shymkent for 2010 to 2012. The efficiency of X-ray screenings in detecting tuberculosis has decreased from 43.5% to 41.0%, and the detection of tuberculosis according to bacterioscopic method has decreased from 24.6% to 19.7 %. However, the number of patients, who have been reinfected with tuberculosis, has reached 58.0 % , or more than half of patients who have been infected for the first time, overall the role of general therapeutic network in the detectio...
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2014 жыл | Шығарылым: 2 | Беттер: 86-88
THE SOCIAL STATUS AND OUTCOMES OF STATIONARY TREATMENT THE PATIENTS BY A TUBERCULOSIS
Among the analyzed patients the unemployeds have made 69,4% suffering - 22,4%, bomsh- 14,7% released (exempted) from places of the conclusion 21,6%.
Among the clinical forms ФКТЛ has made 59,6%, infiltrativni a tuberculosis easy - 32,2%, MBT are found out - in 91,1% of the patients.
The accompanied diseases are revealed at 87,8% of the patients.
The conversion мазка мокроты is achieved at 63,5% of the patients.
Толығырақ
Among the clinical forms ФКТЛ has made 59,6%, infiltrativni a tuberculosis easy - 32,2%, MBT are found out - in 91,1% of the patients.
The accompanied diseases are revealed at 87,8% of the patients.
The conversion мазка мокроты is achieved at 63,5% of the patients.
Толығырақ
2014 жыл | Шығарылым: 2 | Беттер: 84-85
PECULIARITIES OF STAMMS Y. ENTEROCOLITICA TAKEN FROM THE SICK PEOPLE IN SOUTH KAZAKHSTAN AREA
Peculiarities of stamms Y. enterocolitica taken from the sick people were investigated. 93-Stamms Y. Enterocolitica were distinguished from 104 sick ones, 40 from blood, 53 from stool.
According to their morphologic cultural fermentative peculiarities all distinguished Y. Enterocolitica stamms from sick people were typical for the intestine agent of yersiniosis and were belong to cerotypes 03, 08, 09.
Further it was noticed that all distinguished stamms had sensitiveness to 11 antibiotics.
Толығырақ
According to their morphologic cultural fermentative peculiarities all distinguished Y. Enterocolitica stamms from sick people were typical for the intestine agent of yersiniosis and were belong to cerotypes 03, 08, 09.
Further it was noticed that all distinguished stamms had sensitiveness to 11 antibiotics.
Толығырақ
2014 жыл | Шығарылым: 2 | Беттер: 83-84