ФОРМИРОВАНИЕ ОЧАГОВ Р53 СВЯЗАННОГО БЕЛКА 1 В ОПУХОЛЯХ ЩИТОВИДНОЙ ЖЕЛЕЗЫ: АКТИВАЦИЯ ГЕНЕТИЧЕСКОЙ НЕСТАБИЛЬНОСТИ В ТЕЧЕНИИ КАНЦЕРОГЕНЕЗА ЩИТОВИДНОЙ ЖЕЛЕЗЫ. ОБЗОР ЛИТЕРАТУРЫ
Введение: К настоящему времени достигнуты большие успехи в изучении молекулярно–клеточных механизмов канцерогенеза, установлении роли онкогенов и антионкогенов в развитии опухолей различной локализации, в том числе и РЩЖ. Подавляющее число доброкачественных и злокачественных опухолей щитовидной железы развивается из фолликулярного эпителия, которые имеют разную степень дифференцировки, разные морфогенетические и биохимические особенности, клиническое течение и прогноз.
Цель: проведение поиска научной информации по активации генетической нестабильности в течений канцерогенеза щитовидной ... Толығырақ
Цель: проведение поиска научной информации по активации генетической нестабильности в течений канцерогенеза щитовидной ... Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 25-37
ОРГАНИЗАЦИОННЫЕ ОСНОВЫ СКРИНИНГА КОЛОРЕКТАЛЬНОГО РАКА В МИРОВОЙ МЕДИЦИНСКОЙ ПРАКТИКЕ. ОБЗОР ЛИТЕРАТУРЫ
Актуальность. Рак ободочной и прямой кишки (колоректальный) является третьим по распространенности раком в мире. Он поддается скринингу, так как скрининговое исследование может быть осуществлено на предраковых, латентных, ранних и излечимых стадиях. При скрининге колоректального рака могут использоваться прямые или непрямые методы, применяемые произвольно или в структуре организованных программ. Большинство случаев колоректального рака диагностируется в возрасте старше 60 лет. Большинство программ скрининга относятся к лицам в возрасте 50-75 лет.
Цель обзора – Анализ подходов и р... Толығырақ
Цель обзора – Анализ подходов и р... Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 13-24
MODERN TENDENCY IN TREATMENT OF PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY. LITERARY REVIEW
Relevance: Carrying out of intensive therapy at severe traumatic brain injury is a complex of measures aimed on saving of the brain tissues and maintaining its functions. To achieve this goal, it is necessary to do timely diagnostics and monitoring of critical parameters - intracranial pressure and cerebral perfusion pressure; pathogenetically based therapy and nutritional support for critically ill patients.
Aim: The goal of this review was to find evidences of admissibility of use for such methods as control of cerebral perfusion pressure and intracranial pressure, anti-edematous thera... Толығырақ
Aim: The goal of this review was to find evidences of admissibility of use for such methods as control of cerebral perfusion pressure and intracranial pressure, anti-edematous thera... Толығырақ
2019 жыл | Шығарылым: 2 | Беттер: 5-12
ЛЕЧЕНИЕ ПОПЕРЕЧНОГО ПЛОСКОСТОПИЯ С HALLUX VALGUS ПРИ I и II ТИПЕ РАСПЛАСТАННОСТИ СТОПЫ
Введение. Статическая деформация переднего отдела стопы составляет до 80% среди ортопедической патологии стопы у взрослых. Патология вызывает значительное нарушение биомеханики всей нижней конечности, сопровождаясь болью в переднем отделе стопы, затруднение в подборе и ношении обуви, значительно снижает трудоспособность и качество жизни пациента. В связи с этим разработка технологии лечения статической деформации переднего отдела стопы, предусматривающей устранение Halluxvalgus, metatarsusprimavarus и плантарную девиацию центральных лучей стопы остается не полностью решенной и актуальной п...
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2019 жыл | Шығарылым: 1 | Беттер: 80-90
АНТИБИОТИКОРЕЗИСТЕНТНОСТЬ ШИГЕЛЛ НА СОВРЕМЕННОМ ЭТАПЕ
Введение. Одна из больших проблем практического здравоохранения на современном этапе – это рост антибиотикорезистентности шигелл к тем антибактериальным препаратам, которые широко сегодня используются в их лечении.
Цель исследования: изучить чувствительность штаммов Shigella spp., выделенных из кишечника больных острой дизентерией, к широко используемым в клинической практике антимикробным препаратам.
Материалы и методы. Проведен ретроспективный анализ 236 медицинских карт пациентов с диагнозом острой дизентерии, пролеченных на базе Городской инфекционной больница г. Астана за пе... Толығырақ
Цель исследования: изучить чувствительность штаммов Shigella spp., выделенных из кишечника больных острой дизентерией, к широко используемым в клинической практике антимикробным препаратам.
Материалы и методы. Проведен ретроспективный анализ 236 медицинских карт пациентов с диагнозом острой дизентерии, пролеченных на базе Городской инфекционной больница г. Астана за пе... Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 74-79
STEATOTIC LIVER DISEASE: THE IMPACT OF TEA AND COFFEE CONSUMPTION. LITERATURE REVIEW
2025 жыл | Шығарылым: 5 | Беттер: 261-266
LOW KLOTHO LEVELS AND HIGH PLATELET REACTIVITY AS PREDICTORS OF ADVERSE OUTCOMES IN MYOCARDIAL INFARCTION: A CASE-BASED INSIGHT. CLINICAL CASE
2025 жыл | Шығарылым: 5 | Беттер: 267-273
A CASE REPORT OF MYOCARDIAL INFARCT PROCESSED ON POLYMORBID BACKGROUND
2025 жыл | Шығарылым: 5 | Беттер: 274-279
REPROGRAMMING EXPERIENCE OF BLOOD MONONUCLEAR CELLS INTO INDUCED PLURIPOTENT STEM CELLS (IPSCS) IN A PATIENT WITH CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA (CPVT)
2025 жыл | Шығарылым: 4 | Беттер: 7-13
EXPERIENCE OF LONG-TERM OBSERVATION OF AN EXPOSED POPULATION: LESSONS FOR REGIONAL HEALTH MONITORING PROGRAMS
2025 жыл | Шығарылым: 4 | Беттер: 14-20
MOTIVATIONAL MEASURES APPLIED TO PROMOTE THE WORK OF MEDICAL WORKERS: LITERARY REVIEW
Introduction: Human resources are the most important part of any healthcare system, the performance of which depends entirely on the knowledge, skills and motivation of those responsible for providing health services. At the same time, the development of human resources lays in the field of scientific knowledge where there are no simple answers, and refusal to interfere in the market of human capital leads to a backlog formation that can drag on for years and even decades. Stimulation of labor and management of human resources affect the utilization of all resources of any healthcare system. T...
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2018 жыл | Шығарылым: 6 | Беттер: 17-30
QUALITY OF LIFE OF PATIENTS WITH ISCHEMIC HEART DISEASE BEFORE AND AFTER SURGICAL TREATMENT (STENTING AND BYPASSING): LITERARY REVIEW
Introduction. Stenting and bypass surgery is widely introduced into clinical practice of the Republic of Kazakhstan. However, issues of quality of life, health status remain very debatable in scientific circles.
Aim: to analyze the literature devoted to the study of the quality of life and objective state of health of patients before or after surgical treatment of ischemic heart disease, as well as indicators of QALY patients after surgical treatment of ischemic heart disease.
Search strategy: literature search was carried out by manual method using key words (coronary heart di... Толығырақ
Aim: to analyze the literature devoted to the study of the quality of life and objective state of health of patients before or after surgical treatment of ischemic heart disease, as well as indicators of QALY patients after surgical treatment of ischemic heart disease.
Search strategy: literature search was carried out by manual method using key words (coronary heart di... Толығырақ
2018 жыл | Шығарылым: 6 | Беттер: 31-38
APPLICATION OF GEOINFORMATION SYSTEMS IN HEALTH CARE: LITERARY REVIEW
Introduction: Diseases of the circulatory system and trauma are among the leading causes of death in Kazakhstan. The use of geographic information systems and spatial analysis can allow making recommendations for improving the activity for an ambulance station and reducing the number of accidents for public health services.
Objective: To conduct a literature review to determine the possibilities of using geographic informational systems for the needs of the health care system.
Methods: The search for relevant scientific publications in the databases of evidence-based medicine (... Толығырақ
Objective: To conduct a literature review to determine the possibilities of using geographic informational systems for the needs of the health care system.
Methods: The search for relevant scientific publications in the databases of evidence-based medicine (... Толығырақ
2018 жыл | Шығарылым: 6 | Беттер: 39-47
METHODS OF TREATMENT OF EPILEPSY IN CHILDREN WITH TUBEROUS SCLEROSIS. LITERATURE REVIEW.
Relevance: Tuberous sclerosis – a genetic disease with autosomal dominant inheritance pattern with the characteristic of damage of the nervous system, skin and existence of benign tumors (hamartomas) clinical picture. The most frequent manifestation of the disease is epilepsy debuting in the first month of life, which find in 96% of patients. Prevalence, severity of epilepsy associated with tuberous sclerosis, as well as resistance in ongoing therapy and a small number of articles on this issue implies studying of treatment in greater depth and defines the relevance of our literatu...
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2018 жыл | Шығарылым: 6 | Беттер: 48-58
TREATMENT OF TIBIAL SHAFT FRACTURE. LITERATURE REVIEW
Relevance. Fractures of the shin bones, according to various data, occupy the first place, making up fr om 13 to 21.4% of all injuries of the musculoskeletal system, or 64.3 - 70% of fractures of the lower limbs. The frequency of diaphyseal fractures of the bones of the leg is 26-32 cases per 100,000 population per year.
Purpose: The study and analysis of literary data by a study of domestic and foreign authors for the treatment of diaphyseal fractures of the lower leg bones.
Search strategy. A systematic search for scientific information was conducted in the databases of G... Толығырақ
Purpose: The study and analysis of literary data by a study of domestic and foreign authors for the treatment of diaphyseal fractures of the lower leg bones.
Search strategy. A systematic search for scientific information was conducted in the databases of G... Толығырақ
2018 жыл | Шығарылым: 6 | Беттер: 58-69