RADIATION-INDUCED KI-67 PROLIFERATION IN THE SMALL INTESTINE OF RATS
Introduction. It is known that Hiroshima and Nagasaki were target of the first atomic bombs in the history of mankind. As a result, the population of Japanese cities was exposed to internal and external irradiation. Numerous authors maintain that primary neutron-activated radionuclides are chemical elements 56Mn and 60Co. Herewith, 56Mn was determined the dominant role of neutrons induced by β-radiation during the first few hours after the atomic bombing. The systemic access in estimation of Кi-67 marker in radiosensitive small intestine defining the functional state and the interrelation of s...
Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 63-73
EVALUATION OF THE EFFECTIVENESS OF FIRST AID TRAINING IN SHOPPING CENTER EMPLOYEES
Introduction: Cardiopulmonary arrest is on of the most important causes requiring first aid in big metropolis. Cardiac arrest may be often seen in airports, shopping centers (SC), prisons, sports facilities, industrial zones, public transport stations and nursing homes. In this study, we aimed to evaluate effectiveness of training by measuring knowledge level of SC employees before and after first aid training, and to create awareness for the presence and use of automatic external defibrillator.
Material & Methods: Employees of a shopping center were trained for first aid on vol... Толығырақ
Material & Methods: Employees of a shopping center were trained for first aid on vol... Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 58-62
ANALYSIS OF THE PATIENTS ADMITTED TO OUR EMERGENCY DEPARTMENT DUE TO CHRONIC OBSTRUCTIVE PULMONARY DISEASE EXACERBATION
Objective: Chronic Obstructive Pulmonary Disease (COPD) is the fourth most common cause of death in the world according to the reports of the World Health Organisation (WHO). Exacerbations impair the quality of life, fastens the progression of the disease and, thus, plays an important role in the morbidity and mortality of the disease. In this study with, we aimed to investigate the factors effecting the characteristics of the patients admitted to our emergency department (ED) due to COPD exacerbation in term of management, dischargement, hospitalization and ...
Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 50-57
ПРОГНОСТИЧЕСКОЕ ЗНАЧЕНИЕ ПОЧЕЧНОЙ ДИСФУНКЦИИ У БОЛЬНЫХ ИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА ПОСЛЕ РЕВАСКУЛЯРИЗАЦИИ МИОКАРДА
Цель исследования. Изучение распространенности почечной дисфункции (ПД) и ее прогностической значимости у больных ишемической болезнью сердца (ИБС), перенесших реваскуляризацию миокарда.
Материалы и методы. Проведен одномоментный ретроспективный анализ историй болезни 675 пациентов кардиологического отделения, в анамнезе которых - перенесенное чрескожное коронарное вмешательство (ЧКВ) и/или аортокоронарное шунтирование (АКШ). Изучены распространенность факторов риска, особенности коронарного кровотока, структурно-функциональные изменения сердца.
Ста... Толығырақ
Материалы и методы. Проведен одномоментный ретроспективный анализ историй болезни 675 пациентов кардиологического отделения, в анамнезе которых - перенесенное чрескожное коронарное вмешательство (ЧКВ) и/или аортокоронарное шунтирование (АКШ). Изучены распространенность факторов риска, особенности коронарного кровотока, структурно-функциональные изменения сердца.
Ста... Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 42-49
ПОСЛЕОПЕРАЦИОННЫЕ ВЕНТРАЛЬНЫЕ ГРЫЖИ. ХИРУРГИЧЕСКОЕ ЛЕЧЕНИЕ И ПРОФИЛАКТИКА РАНЕВЫХ ОСЛОЖНЕНИЙ. ОБЗОР ЛИТЕРАТУРЫ
Введение. В современной Казахстанской и зарубежной литературе немалое число работ посвящено изучению послеоперационных вентральных грыж. Однако результаты их хирургического лечения не всегда устраивают как клиницистов, так и самих пациентов [5, 9, 47, 53, 55, 74]. Развитие инфекционных раневых осложнений в послеоперационном периоде - одна из причин увеличения длительности госпитализации, возникновения рецидива грыжи, роста расходов на лечение [34, 76, 78, 79].
Цель. Провести обзор литературных данных по вопросам хирургического лечения послеоперационных вентральных грыж и профилактики ран... Толығырақ
Цель. Провести обзор литературных данных по вопросам хирургического лечения послеоперационных вентральных грыж и профилактики ран... Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 29-41
COMPARATIVE EVALUATION OF BLOOD COLLECTION TUBES AND EXTRACTION METHODS FOR CIRCULATING TUMOR DNA
2025 жыл | Шығарылым: 6 | Беттер: 7-13
INFLUENCE OF SEX HORMONE-BINDING GLOBULIN (SHBG) ON THE LEVEL OF FREE TESTOSTERONE FRACTION IN OLDER OVERWEIGHT MEN
2025 жыл | Шығарылым: 6 | Беттер: 14-20
GENETIC VARIANTS IN LIPID-ASSOCIATED GENES IN THE KAZAKHSTANI COHORT WITH ATHEROSCLEROSIS AND HYPERTRIGLYCERIDEMIA
2025 жыл | Шығарылым: 5 | Беттер: 7-15
CLONAL HEMATOPOIESIS WITH INDETERMINATE POTENTIAL IN TET2 AND DNMT3A AMONG KAZAKHSTANI INDIVIDUALS WITH ATHEROSCLEROTIC DISEASE
2025 жыл | Шығарылым: 5 | Беттер: 16-23
HYPERHOMOCYSTEINEMIA AS A RISK FACTOR OF CARDIOVASCULAR DISEASES
Cardiovascular diseases are the leading cause of death. In this regard, the importance of the prevention problem increases, which is aimed at the identification and elimination of risk factors, which include elevated levels of homocysteine in the blood.
In recent years, actively studying the possibility of the use of B vitamins in vascular and neurodegenerative diseases. One of the main factors of hyperhomocysteinemia is the deficiency of vitamins B6, B12, B9 resulting from the features of the diet and impaired absorption. It was found that the use of preparations of B vitamins can reduc... Толығырақ
In recent years, actively studying the possibility of the use of B vitamins in vascular and neurodegenerative diseases. One of the main factors of hyperhomocysteinemia is the deficiency of vitamins B6, B12, B9 resulting from the features of the diet and impaired absorption. It was found that the use of preparations of B vitamins can reduc... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 129-144
MOLECULAR TYPE OF BREAST CANCER AS PROGNOSTIC FACTOR FOR METASTASIS
Introduction: The article provides an overview of the literature data on the peculiarities of metastasis of different subtypes of breast cancer (BC), which is characterized by heterogeneity, malignancy, early and rapid lymphatic and hematogenous metastasis. Modern studies have shown about the connection between the molecular type and localization of metastatic breast cancer.
Objective: Analysis of published data about the features of different molecular subtypes of breast cancer metastasis.
Materials and Methods: publications searched in the following databases: PubMed Med... Толығырақ
Objective: Analysis of published data about the features of different molecular subtypes of breast cancer metastasis.
Materials and Methods: publications searched in the following databases: PubMed Med... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 119-128
ASSOCIATION OF POLYMORPHISMS OF GENES OF IL1B (RS1143627), IL10 (RS1800896), IL17А (RS 2275913, RS8193036) WITH INFECTIOUS DISEASES INCLUDING ERYSIPELAS
The investigate of polymorphism of cytokine genes is an important in pathogenesis of many diseases and in identifying susceptibility to them. Knowledge of their role in the pathogenesis of many diseases, particularly infectious diseases are permits, on the one hand, to predict risk of disease or severity of its flow, on the other - to pick up individually specific therapy for a particular patient.
Despite the fact that to date, in the literature there are a significant number of studies that found an association between polymorphisms of cytokine genes and susceptibility to infectious dis... Толығырақ
Despite the fact that to date, in the literature there are a significant number of studies that found an association between polymorphisms of cytokine genes and susceptibility to infectious dis... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 104-118
STRUCTURE AND FREQUENCY OF CHILDBIRTH COMPLICATIONS OF MACROSOMIA
The relevance study macrosomia’s problem lies in the fact that the great mass of the fetus at birth is associated with increased frequency of obstetric pathology, which in turn leads to an increase in perinatal mortality and have a negative impact on the further development of children [11,12,13,14,15].
Research objectives: Determine the structure of childbirth complications and the frequency at macrosomia.
Materials and Methods: Study design: US -skrining. The study group included 147 birth stories with large fetus. Selection of cases in the control group held "random digits ... Толығырақ
Research objectives: Determine the structure of childbirth complications and the frequency at macrosomia.
Materials and Methods: Study design: US -skrining. The study group included 147 birth stories with large fetus. Selection of cases in the control group held "random digits ... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 93-103
DIAGNOSTIC VALUE OF MACROSOMIAS PREDICTOR
Determination of the expected weight of the fetus and the diagnosis of complications in childbirth remains debated issue. To select the optimum tactics of labor with large fetus and reduce the complications accurate methods of prenatal prediction of macrosomia are required.
Research objectives: to evaluate the diagnostic value of ultrasound measurement of abdominal circumference, as a predictor of macrosomia.
Materials and Methods: Study design: US -skrining. The study group included 147 birth stories with large fetus. Selection of cases in the control group held "random digit... Толығырақ
Research objectives: to evaluate the diagnostic value of ultrasound measurement of abdominal circumference, as a predictor of macrosomia.
Materials and Methods: Study design: US -skrining. The study group included 147 birth stories with large fetus. Selection of cases in the control group held "random digit... Толығырақ
2016 жыл | Шығарылым: 4 | Беттер: 84-92