RADIATION-INDUCED KI-67 PROLIFERATION IN THE SMALL INTESTINE OF RATS
Introduction. It is known that Hiroshima and Nagasaki were target of the first atomic bombs in the history of mankind. As a result, the population of Japanese cities was exposed to internal and external irradiation. Numerous authors maintain that primary neutron-activated radionuclides are chemical elements 56Mn and 60Co. Herewith, 56Mn was determined the dominant role of neutrons induced by β-radiation during the first few hours after the atomic bombing. The systemic access in estimation of Кi-67 marker in radiosensitive small intestine defining the functional state and the interrelation of s...
Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 63-73
EVALUATION OF THE EFFECTIVENESS OF FIRST AID TRAINING IN SHOPPING CENTER EMPLOYEES
Introduction: Cardiopulmonary arrest is on of the most important causes requiring first aid in big metropolis. Cardiac arrest may be often seen in airports, shopping centers (SC), prisons, sports facilities, industrial zones, public transport stations and nursing homes. In this study, we aimed to evaluate effectiveness of training by measuring knowledge level of SC employees before and after first aid training, and to create awareness for the presence and use of automatic external defibrillator.
Material & Methods: Employees of a shopping center were trained for first aid on vol... Толығырақ
Material & Methods: Employees of a shopping center were trained for first aid on vol... Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 58-62
ANALYSIS OF THE PATIENTS ADMITTED TO OUR EMERGENCY DEPARTMENT DUE TO CHRONIC OBSTRUCTIVE PULMONARY DISEASE EXACERBATION
Objective: Chronic Obstructive Pulmonary Disease (COPD) is the fourth most common cause of death in the world according to the reports of the World Health Organisation (WHO). Exacerbations impair the quality of life, fastens the progression of the disease and, thus, plays an important role in the morbidity and mortality of the disease. In this study with, we aimed to investigate the factors effecting the characteristics of the patients admitted to our emergency department (ED) due to COPD exacerbation in term of management, dischargement, hospitalization and ...
Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 50-57
ПРОГНОСТИЧЕСКОЕ ЗНАЧЕНИЕ ПОЧЕЧНОЙ ДИСФУНКЦИИ У БОЛЬНЫХ ИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА ПОСЛЕ РЕВАСКУЛЯРИЗАЦИИ МИОКАРДА
Цель исследования. Изучение распространенности почечной дисфункции (ПД) и ее прогностической значимости у больных ишемической болезнью сердца (ИБС), перенесших реваскуляризацию миокарда.
Материалы и методы. Проведен одномоментный ретроспективный анализ историй болезни 675 пациентов кардиологического отделения, в анамнезе которых - перенесенное чрескожное коронарное вмешательство (ЧКВ) и/или аортокоронарное шунтирование (АКШ). Изучены распространенность факторов риска, особенности коронарного кровотока, структурно-функциональные изменения сердца.
Ста... Толығырақ
Материалы и методы. Проведен одномоментный ретроспективный анализ историй болезни 675 пациентов кардиологического отделения, в анамнезе которых - перенесенное чрескожное коронарное вмешательство (ЧКВ) и/или аортокоронарное шунтирование (АКШ). Изучены распространенность факторов риска, особенности коронарного кровотока, структурно-функциональные изменения сердца.
Ста... Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 42-49
ПОСЛЕОПЕРАЦИОННЫЕ ВЕНТРАЛЬНЫЕ ГРЫЖИ. ХИРУРГИЧЕСКОЕ ЛЕЧЕНИЕ И ПРОФИЛАКТИКА РАНЕВЫХ ОСЛОЖНЕНИЙ. ОБЗОР ЛИТЕРАТУРЫ
Введение. В современной Казахстанской и зарубежной литературе немалое число работ посвящено изучению послеоперационных вентральных грыж. Однако результаты их хирургического лечения не всегда устраивают как клиницистов, так и самих пациентов [5, 9, 47, 53, 55, 74]. Развитие инфекционных раневых осложнений в послеоперационном периоде - одна из причин увеличения длительности госпитализации, возникновения рецидива грыжи, роста расходов на лечение [34, 76, 78, 79].
Цель. Провести обзор литературных данных по вопросам хирургического лечения послеоперационных вентральных грыж и профилактики ран... Толығырақ
Цель. Провести обзор литературных данных по вопросам хирургического лечения послеоперационных вентральных грыж и профилактики ран... Толығырақ
2019 жыл | Шығарылым: 1 | Беттер: 29-41
COMPARATIVE EVALUATION OF BLOOD COLLECTION TUBES AND EXTRACTION METHODS FOR CIRCULATING TUMOR DNA
2025 жыл | Шығарылым: 6 | Беттер: 7-13
INFLUENCE OF SEX HORMONE-BINDING GLOBULIN (SHBG) ON THE LEVEL OF FREE TESTOSTERONE FRACTION IN OLDER OVERWEIGHT MEN
2025 жыл | Шығарылым: 6 | Беттер: 14-20
GENETIC VARIANTS IN LIPID-ASSOCIATED GENES IN THE KAZAKHSTANI COHORT WITH ATHEROSCLEROSIS AND HYPERTRIGLYCERIDEMIA
2025 жыл | Шығарылым: 5 | Беттер: 7-15
CLONAL HEMATOPOIESIS WITH INDETERMINATE POTENTIAL IN TET2 AND DNMT3A AMONG KAZAKHSTANI INDIVIDUALS WITH ATHEROSCLEROTIC DISEASE
2025 жыл | Шығарылым: 5 | Беттер: 16-23
REDUCTION OF CONGENITAL MALFORMATION FREQUENCY ACCORDING TO THE DATA OF GENETIC SERVICE OF PERINATAL CENTER OF SEMEY CITY FROM 2010 TO THE FIRST HALF OF 2015
Congenital malformations (CM) are heterogenic group of pathological states which include isolated, system and multiple abnormalities of organs and systems of different etiology: genetic, environmental and multifactorial [6]. CMs are serious medical and social problem that related to increase of specific weight of abnormal development in structure of perinatal child mortality and disability. Among newborns, frequency of CM defined during the first year of life reaches 5%. [8]. CM are leaders in reason structure of perinatal mortality.
The aim of research is study of statistica... Толығырақ
The aim of research is study of statistica... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 103-112
COMPARATIVE EVALUATION OF PAIN SYNDROME OF OPERATED PATIENTS WITH INGUINAL HERNIAS
A comparative evaluation of operated patients with inguinal hernia in Medical Center Semey State Medical University fr om 2008 to 2015 year was performed. Patients of the main group were operated by our developed the method. The proposed method has advantages over traditional methods of plastics, is a universal intervention for large inguinal-scrotal and recurrent inguinal hernias. The technique allows to strengthen simultaneously the anterior and posterior wall of the inguinal canal, the inguinal ligament and the femoral canal, which leads to less pain in the postoperative period and the abse...
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 93-102
EFFECT OF EXTRACT ON ACTIVITY OF ENERGY METABOLISM ENZYMES AFTER COMBINED EFFECT OF EMOTIONAL STRESS AND SUBLETHAL DOSE OF γ-RADIATION IN REMOTE PERIOD
Introduction. During adaptation process complex changes occur in metabolic pathways; functional and structural changes occur in organs and tissue. Despite the great interest of researchers to this problem, the pathogenetic mechanisms of influence of stress, especially combined effect of stressors on the metabolic processes hasn’t been studied enough. Main criterion for the stability of the adaptive behavior of the organism is to maintain energy potential of biosystems constant. Given the importance of this system, it is necessary to define its role in formation of pathological process in anima...
Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 67-78
THE FREQUENCY OF POLYMORPHISMS OF THE GENE 5382insC BRCA1 IN PATIENTS WITH FAMILIAL BREAST CANCERS ARE EXPOSED TO IONIZING RADIATION AS A RESULT OF SEMIPALATINSK NUCLEAR TEST SITE AND THEIR DESCENDANTS
Genetic changes play an important role among the risk factors for breast cancer, but their mechanisms of and contribution to the development of the disease is not finalized.
Purpose of the study: determining the frequency of the BRCA1 gene polymorphism 5382insC in patients with familial breast cancers in the region radiological trouble Semipalatinsk nuclear test site in the first and second generations of irradiated.
Materials and methods: The study included 250 women aged 40 to 79 years, Kazakh nationality, including 190 breast cancer patients, distributed in groups. The first gro... Толығырақ
Purpose of the study: determining the frequency of the BRCA1 gene polymorphism 5382insC in patients with familial breast cancers in the region radiological trouble Semipalatinsk nuclear test site in the first and second generations of irradiated.
Materials and methods: The study included 250 women aged 40 to 79 years, Kazakh nationality, including 190 breast cancer patients, distributed in groups. The first gro... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 58-66
FACTORS, ASSOCIATED WITH ONE YEAR SURVIVAL AFTER STROKE IN KAZAKHSTAN: A COHORT STUDY
Introduction. Many unresolved question exist about the predictors of stroke outcome. The evidence on the determinants of stroke survival in Kazakhstan is very scarce, despite the high prevalence of the problem.
The aim: To study factors associated with one -year stroke survival in a population of Semey, Kazakhstan.
Methods. All cases of stroke were included in a cohort in Semey from 01.01.2014 to 31.12.15 (N = 937).Survival of patients with stroke was assessed using Kaplan-Mayer curves and log-rank tests. Independent associations of the studied factors with survival were s... Толығырақ
The aim: To study factors associated with one -year stroke survival in a population of Semey, Kazakhstan.
Methods. All cases of stroke were included in a cohort in Semey from 01.01.2014 to 31.12.15 (N = 937).Survival of patients with stroke was assessed using Kaplan-Mayer curves and log-rank tests. Independent associations of the studied factors with survival were s... Толығырақ
2016 жыл | Шығарылым: 3 | Беттер: 46-57